Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Yanzheng Gu"'
Autor:
Yuhong Zhang, Yufeng Ling, Ying Zhou, Xiu Shi, Fangrong Shen, Jinhua Zhou, Youguo Chen, Fan Yang, Yanzheng Gu, Juan Wang
Publikováno v:
Cancer Control, Vol 31 (2024)
Ovarian cancer (OC) is the most lethal gynecological tumor, characterized by its insidious and frequently recurring metastatic progression. Owing to limited early screening methods, over 70% of OC cases are diagnosed at advanced stages, typically sta
Externí odkaz:
https://doaj.org/article/8457e1bc50a74f1ca0b749b2d37ef18b
Autor:
Yang Li MS, Wenwen Wang BS, Jingluan Tian MD, Ying Zhou MS, Yu Shen BS, Mingyuan Wang MD, Longhai Tang MD, Cuiping Liu MD, Xueguang Zhang MD, Fangrong Shen MD, Youguo Chen MD, Yanzheng Gu MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Background: The tumor microenvironment and tumor immunity have become the focus of research on tumor diagnosis and treatment. Lymphocyte activation gene-3 (LAG-3, CD223) is a newly discovered immunosuppressive receptor that is abnormally expressed in
Externí odkaz:
https://doaj.org/article/aa88682a25b147eda7879400d825c7e7
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
The mortality rate of cervical cancer is the highest among female malignant tumors and seriously threatens women's lives and health. Persistent high-risk human papillomavirus (HPV) infection is the leading cause of cervical cancer, which provides the
Externí odkaz:
https://doaj.org/article/3dc205a6e8c44750a5b07f5d48c72479
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inducible costimulator (ICOS) and its ligand (ICOSL) are critical to regulate the immune response in autoimmune diseases. The participation of B lymphocytes exhibits pathogenic potential in the disease process of rheumatoid arthritis (RA). However, t
Externí odkaz:
https://doaj.org/article/0f9c075460df40edaf9f1e3089efccac
Autor:
Rong Jiang, Hongyu Zhang, Jinhua Zhou, Juan Wang, Yuejuan Xu, He Zhang, Yanzheng Gu, Fengqing Fu, Yu Shen, Guangbo Zhang, Lanlan Feng, Xueguang Zhang, Youguo Chen, Fangrong Shen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-12 (2021)
Abstract Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play critical roles in human diseases. We aimed to clarify the role of lncRNA X-inactive specific transcript (XIST)/miR-149-3p/forkhead box P3 (FOXP3) axis in ovarian cancer (OC) cell gro
Externí odkaz:
https://doaj.org/article/23770bb1a56842e082b76d7eb75bcba5
Autor:
Xiaoling Zhou, Xiaoyuan Wang, Yanzheng Gu, Lan Chen, Yueping Shen, Jingluan Tian, Chen Shujun, Mingyuan Wang, Xiaoyu Duan, Hanqing Gao, Xiaopei Ji, Qi Fang, Xueguang Zhang, Qun Xue
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Background. A previous study on thymomas in myasthenia gravis (MG) patients indicated that OX40 expression may be upregulated in thymic tissues adjacent to germinal centers (GCs) and thymomas, and OX40 may interact with OX40L in GCs to enhance anti-a
Externí odkaz:
https://doaj.org/article/b416c842acdf497c9c0c0c41ee3f790c
Autor:
Qun Xue, Xiaoping Li, Yanzheng Gu, Xiaozhu Wang, Mingyuan Wang, Jingluan Tian, Xiaoyu Duan, Hanqing Gao, Xiaopei Ji, Xiaoming Yan, Wanli Dong, Qi Fang, Xueguang Zhang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/3810f4c054e44657b5526acd0d666229
Autor:
Runzi Sun, Yixian Wu, Huijun Zhou, Yanshi Wu, Zhongzhou Yang, Yanzheng Gu, Jingting Jiang, Binfeng Lu, Yibei Zhu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Sustaining efficacious T cell-mediated antitumor immune responses in the tumor tissues is the key to the success of cancer immunotherapy. Current strategies leverage altering the signals T cells sense in the tumor microenvironment (TME). Checkpoint i
Externí odkaz:
https://doaj.org/article/4e66d033192c43999ec716c88edbd213
Autor:
Honghong He, Liyan Shi, Dan Meng, Huijun Zhou, Jingshu Ma, Yixian Wu, Yanshi Wu, Yanzheng Gu, Wei Xie, Jing Zhang, Yibei Zhu
Publikováno v:
Cancer Treatment and Research Communications, Vol 28, Iss , Pp 100379- (2021)
PD-1 immune checkpoint blockade and cytokine IL-33 have shown significant therapeutic effects in tumor immunotherapy. These therapies promote CD8+ T cell activation, proliferation, and effector functions. However, there were few research about the co
Externí odkaz:
https://doaj.org/article/c073d1a400ae443bb3f48d53322cf794
Autor:
Hongyu Zhang, Rong Jiang, Jinhua Zhou, Juan Wang, Yuejuan Xu, He Zhang, Yanzheng Gu, Fengqing Fu, Yu Shen, Guangbo Zhang, Lanlan Feng, Xueguang Zhang, Youguo Chen, Fangrong Shen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: Cancer-associated fibroblasts (CAFs) were associated with tumor progression in the tumor microenvironment (TME). However, their immunosuppressive roles in protecting cancer cells from the attack by cytotoxic T lymphocytes (CTLs) are not fu
Externí odkaz:
https://doaj.org/article/76e115eb5380496b8c8ec253bbabdbc0