Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yanzhao Zhong"'
Autor:
Jing Wang, Qiyao Chai, Zehui Lei, Yiru Wang, Jiehua He, Pupu Ge, Zhe Lu, Lihua Qiang, Dongdong Zhao, Shanshan Yu, Changgen Qiu, Yanzhao Zhong, Bing-Xi Li, Lingqiang Zhang, Yu Pang, George Fu Gao, Cui Hua Liu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1755-1790 (2024)
Abstract Chronic infections, including Mycobacterium tuberculosis (Mtb)-caused tuberculosis (TB), can induce host immune exhaustion. However, the key checkpoint molecules involved in this process and the underlying regulatory mechanisms remain largel
Externí odkaz:
https://doaj.org/article/ae6f6b1e577e473187f3a8bfd0f24742
Autor:
Qiyao Chai, Xudong Wang, Lihua Qiang, Yong Zhang, Pupu Ge, Zhe Lu, Yanzhao Zhong, Bingxi Li, Jing Wang, Lingqiang Zhang, Dawang Zhou, Wei Li, Wenzhu Dong, Yu Pang, George Fu Gao, Cui Hua Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Ubiquitin (Ub)-mediated xenophagy is important in defense against Mycobacterium tuberculosis (Mtb). Here, Chai et al. describe autophagy triggering by Ub binding to the Mtb surface protein Rv1468c, and show that its deletion leads to increased bacter
Externí odkaz:
https://doaj.org/article/74d2a3ea423348b2880c9a031a9391b8
Autor:
Qiyao Chai, Shanshan Yu, Yanzhao Zhong, Zhe Lu, Changgen Qiu, Yang Yu, Xinwen Zhang, Yong Zhang, Zehui Lei, Lihua Qiang, Bing-Xi Li, Yu Pang, Xiao-Bo Qiu, Jing Wang, Cui Hua Liu
Publikováno v:
Science (New York, N.Y.). 378(6616)
The inflammasome-mediated cleavage of gasdermin D (GSDMD) causes pyroptosis and inflammatory cytokine release to control pathogen infection, but how pathogens evade this immune response remains largely unexplored. Here we identify the known protein p
Autor:
Jing Wang, Qiyao Chai, Yanzhao Zhong, Lingqiang Zhang, Yong Zhang, Wenzhu Dong, Cui Hua Liu, George F. Gao, Pupu Ge, Yu Pang, Dawang Zhou, Wei Li, Xudong Wang, Bingxi Li, Zhe Lu, Lihua Qiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Ubiquitin-mediated xenophagy, a type of selective autophagy, plays crucial roles in host defense against intracellular pathogens including Mycobacterium tuberculosis (Mtb). However, the exact mechanism by which host ubiquitin targets invaded microbes
Autor:
Cui Hua Liu, Jing Wang, Qiyao Chai, Changgen Qiu, Zhe Lu, Yanzhao Zhong, Lingqiang Zhang, Fuzhen Zhang, Bingxi Li, Zhidong Liu, Yu Pang
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-17 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-17 (2020)
Previous reports have suggested a link between pulmonary tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), and the development of lung adenocarcinoma (LUAD) and sarcoidosis. Furthermore, these lung diseases share certain clinica