Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yanyun, Du"'
Autor:
Yanyun Du, Qianwen Peng, Du Cheng, Ting Pan, Wanwei Sun, Heping Wang, Xiaojian Ma, Ruirui He, Huazhi Zhang, Zhihui Cui, Xiong Feng, Zhiqiang Liu, Tianxin Zhao, Wenjun Hu, Lei Shen, Wenyang Jiang, Na Gao, Bradley N. Martin, Cun-Jin Zhang, Zhanguo Zhang, Chenhui Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Cancer cells producing ligands for the immune checkpoint molecules PD-1 and CTLA-4 is an important mechanism of tumour immune resistance. Here authors show that BTNL2 expression on cancer cells generates a dysfunctional tumour immune microenvironment
Externí odkaz:
https://doaj.org/article/bc2c48f5c4eb46b6b81e3b0918f911d1
Autor:
Ruirui He, Jianwen Chen, Ziyan Zhao, Changping Shi, Yanyun Du, Ming Yi, Lingyun Feng, Qianwen Peng, Zhihui Cui, Ru Gao, Heping Wang, Yi Huang, Zhi Liu, Chenhui Wang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Common variants of the T-cell activation Rho GTPase-activating protein (TAGAP) are associated with the susceptibility to human inflammatory bowel diseases (IBDs); however, the underlying mechanisms are still unknown. Here, we show that TAGAP deficien
Externí odkaz:
https://doaj.org/article/06bf00711e9a4ce6aaf48d100b564d1b
Autor:
Yanyun Du, Rui Shi, Ying Zhang, Xiaomin Duan, Li Li, Jing Zhang, Fengze Wang, Ruixue Zhang, Hao Shen, Yue Wang, Zheng Wu, Qianwen Peng, Ting Pan, Wanwei Sun, Weijin Huang, Yue Feng, Hui Feng, Junyu Xiao, Wenjie Tan, Youchun Wang, Chenhui Wang, Jinghua Yan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here the authors report the isolation and structural and biological characterization of a humanized angiotensin-converting enzyme 2 (ACE2)-blocking antibody, which exterts potent inhibitory activity against SARS-CoV and circulating global SARS-CoV-2
Externí odkaz:
https://doaj.org/article/97a9b5fb5db54f02ba7db4036da85f1f
Autor:
Jianwen Chen, Ruirui He, Wanwei Sun, Ru Gao, Qianwen Peng, Liwen Zhu, Yanyun Du, Xiaojian Ma, Xiaoli Guo, Huazhi Zhang, Chengcheng Tan, Junhan Wang, Wei Zhang, Xiufang Weng, Jianghong Man, Hermann Bauer, Qing K. Wang, Bradley N. Martin, Cun-Jin Zhang, Xiaoxia Li, Chenhui Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
TAGAP gene variants are linked to human autoimmunity. Here the authors identify TAGAP as a Dectin-1 and EphB2-binding protein mediating antifungal innate immune signaling and cytokine production, and demonstrate TAGAP in non-T cells promotes Th17 res
Externí odkaz:
https://doaj.org/article/69258493889b41e28feb66c907a43116
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/6c9767c672e2433ba71e2afd2635ba8a
Autor:
Huazhi Zhang, Zhihui Cui, Ting Pan, Huijun Hu, Ruirui He, Ming Yi, Wanwei Sun, Ru Gao, Heping Wang, Xiaojian Ma, Qianwen Peng, Xiong Feng, Shuyan Liang, Yanyun Du, Chenhui Wang
Publikováno v:
J Immunol
The receptor tyrosine kinase EPHB2 (EPH receptor B2) is highly expressed in many human cancer types, especially in gastrointestinal cancers, such as colorectal cancer. Several coding mutations of the EPHB2 gene have been identified in many cancer typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7a8376de85493c9f11e5d856d07194
https://doi.org/10.4049/jimmunol.2200229
https://doi.org/10.4049/jimmunol.2200229
Autor:
Siyu Wang, Jie Li, Yanyun Du, Yujia Xu, Yali Wang, Zubin Zhang, Zhuan Xu, Yuanying Zeng, Xinliang Mao, Biyin Cao
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 4, Pp 197-202 (2017)
S14161 is a pan-Class I PI3K inhibitor that induces blood cancer cell death, but its mechanism is largely unknown. In the present study, we evaluated the role of S14161 in autophagy, an emerging event in cell destination. Multiple myeloma cell lines
Externí odkaz:
https://doaj.org/article/a73ea2c350c74715b37efaa11bcc36de
Autor:
Xiaojian Ma, Xi Tan, Bingbing Yu, Wanwei Sun, Heping Wang, Huijun Hu, Yanyun Du, Ruirui He, Ru Gao, Qianwen Peng, Zhihui Cui, Ting Pan, Xiong Feng, Junhan Wang, Chengqi Xu, Bin Zhu, Wei Liu, Chenhui Wang
Publikováno v:
Cellular and Molecular Immunology
Fungal infections cause ~1.5 million deaths each year worldwide, and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria. The major reasons for the high mortality of candidiasis are the limited number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e451ece4d045c14a7af7f575af774f
https://doi.org/10.1038/s41423-021-00835-0
https://doi.org/10.1038/s41423-021-00835-0
Autor:
Qianwen Peng, Ting Pan, Ruirui He, Ming Yi, Lingyun Feng, Zhihui Cui, Ru Gao, Heping Wang, Xiong Feng, Hui Li, Yuan Wang, Cun‐jin Zhang, Du Cheng, Yanyun Du, Chenhui Wang
Publikováno v:
EMBO reports. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47a837a725bf49ebe11d2698b6cde4a
https://doi.org/10.15252/embr.202256034
https://doi.org/10.15252/embr.202256034
Autor:
Xiaojian Ma, Zhihui Cui, Yue-Ying Wang, Songfang Wu, Yanyun Du, Huazhi Zhang, Ruirui He, Liwen Zhu, Cun-Jin Zhang, Chenhui Wang, Bradley N. Martin, Qianwen Peng, Heping Wang, Ru Gao, Jianwen Chen, Huijun Hu, Wanwei Sun
Publikováno v:
The Journal of Immunology. 206:2353-2365
IL-17A plays an essential role in the pathogenesis of many autoimmune diseases, including psoriasis and multiple sclerosis. Act1 is a critical adaptor in the IL-17A signaling pathway. In this study, we report that an anti-sense long noncoding RNA, TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4282bdabde09ab0b048172b4364d4618
https://doi.org/10.4049/jimmunol.2001223
https://doi.org/10.4049/jimmunol.2001223