Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yanyan Ruan"'
Autor:
Zhiliu Wu, Jian Qin, Yang You, Yuanlin Ma, Meixiang Jia, Linyan Wang, Tianlan Lu, Weihua Yue, Yanyan Ruan, Dai Zhang, Jun Li, Lifang Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Multiple epidermal growth factor-like-domains 10 (MEGF10), a critical member of the apoptotic engulfment pathway, mediates axon pruning and synapse elimination during brain development. Previous studies indicated that synaptic pruning defici
Externí odkaz:
https://doaj.org/article/165798ae1fd54a70a205526485ea507d
Autor:
Jun Li, Yang You, Weihua Yue, Meixiang Jia, Hao Yu, Tianlan Lu, Zhiliu Wu, Yanyan Ruan, Lifang Wang, Dai Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142887 (2015)
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders. Recent studies suggested that calcium channel genes might be involved in the genetic etiology of ASD. CACNA1A, encoding an alpha-1 subunit of voltage-gated calcium channel,
Externí odkaz:
https://doaj.org/article/9e0062f0f16e469aa0997bfb9201b1aa
Autor:
Jun Li, Linnan Zhao, Yang You, Tianlan Lu, Meixiang Jia, Hao Yu, Yanyan Ruan, Weihua Yue, Jing Liu, Lin Lu, Dai Zhang, Lifang Wang
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133247 (2015)
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with a strong genetic component. Many lines of evidence indicated that ASD shares common genetic variants with other psychiatric disorders (for example, schizophrenia). Previou
Externí odkaz:
https://doaj.org/article/8f0cfadca6b746ba969e1f98023fc7d5
Autor:
Fuquan Zhang, Chenxing Liu, Yong Xu, Guoyang Qi, Guozhen Yuan, Zaohuo Cheng, Jidong Wang, Guoqiang Wang, Zhiqiang Wang, Wei Zhu, Zhenhe Zhou, Xingfu Zhao, Lin Tian, Chunhui Jin, Janmin Yuan, Guofu Zhang, Yaguang Chen, Lifang Wang, Tianlan Lu, Hao Yan, Yanyan Ruan, Weihua Yue, Dai Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86037 (2014)
Schizophrenia (SZ) is a neurodevelopmental disorder in which altered immune function typically plays an important role in mediating the effect of environmental insults and regulation of inflammation. The breast cancer suppressor protein associated pr
Externí odkaz:
https://doaj.org/article/33a1c773f5bb488e9d3883b322a4405e
Autor:
Lifang Wang, Jun Li, Yanyan Ruan, Tianlan Lu, Chenxing Liu, Meixiang Jia, Weihua Yue, Jing Liu, Thomas Bourgeron, Dai Zhang
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53727 (2013)
Melatonin is involved in the regulation of circadian and seasonal rhythms and immune function. Prior research reported low melatonin levels in autism spectrum disorders (ASD). ASMT located in pseudo-autosomal region 1 encodes the last enzyme of the m
Externí odkaz:
https://doaj.org/article/d69e640698c74c0f9ef7210d9944ee34
Autor:
Wen Yang, Jing Liu, Fanfan Zheng, Meixiang Jia, Linnan Zhao, Tianlan Lu, Yanyan Ruan, Jishui Zhang, Weihua Yue, Dai Zhang, Lifang Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61021 (2013)
BACKGROUND:Autism is a neurodevelopmental disorder with a high estimated heritability. ATP2B2, located on human chromosome 3p25.3, encodes the plasma membrane calcium-transporting ATPase 2 which extrudes Ca(2+) from cytosol into extracellular space.
Externí odkaz:
https://doaj.org/article/34ab66ce8d214e4d8ff18fcf926d96d3
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56732 (2013)
Chromosome 6p21-p22.1, spanning the extended major histocompatibility complex (MHC) region, is a highly polymorphic, gene-dense region. It has been identified as a susceptibility locus of schizophrenia in Europeans, Japanese, and Chinese. In our prev
Externí odkaz:
https://doaj.org/article/e4302397342b474b9c32e627803bd32c
Autor:
Weihua Yue, Dai Zhang, Jun Li, Yanyan Ruan, Lifang Wang, Ziqi Wang, Mei Shuang, Tianlan Lu, Tian Zhang, Linyan Wang, Meixiang Jia, Zhiliu Wu, Jing Liu
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-12 (2018)
Translational Psychiatry
Translational Psychiatry
Cytogenetic studies suggested that chromosome 15q11-q13 might be a candidate region that increases the risk of autism. Previous association studies in Caucasian populations identified the risk variants of genes in this region. However, the associatio
Autor:
Meixiang Jia, Dai Zhang, Yanyan Ruan, Linyan Wang, Jing Liu, Ye Tian, Zhiliu Wu, Lifang Wang, Tianlan Lu
Publikováno v:
The World Journal of Biological Psychiatry. 18:143-150
Autism is a pervasive neurodevelopmental disorder with high heritability. Genetic factors play crucial roles in the aetiology of autism. Dual specificity phosphatase 15 (DUSP15) has been recognised as a key regulator gene for oligodendrocytes differe
Publikováno v:
Neuroscience Bulletin. 32:239-245
It has been suggested that altered neurogenesis may be involved in the etiology of schizophrenia, so genes impacting on neurogenesis could be potential candidates for schizophrenia. A member of the Musashi family, the human MSI2 gene plays a substant