Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yanxin Chang"'
Autor:
Yanxin Chang, Xuying Wan, Xiaohui Fu, Ziyu Yang, Zhijie Lu, Zhenmeng Wang, Li Fu, Lei Yin, Yongjie Zhang, Qian Zhang
Publikováno v:
Aging. 14:544-556
The wide spread of coronavirus disease 2019 is currently the most rigorous health threat, and the clinical outcomes of severe patients are extremely poor. In this study, we establish an early warning nomogram model related to severe versus common COV
TMEM106C contributes to the malignant characteristics and poor prognosis of hepatocellular carcinoma
Autor:
Youwen Qian, Yanxin Chang, Chen Meiling, Xiaohui Fu, Chen Liu, Jiahe Yang, Kai Liu, Jicheng Duan, Hu Liu
Publikováno v:
Aging (Albany NY)
Transmembrane protein (TMEM) is a kind of integral membrane protein that spans biological membranes. The functions of most members of the TMEM family are unknown. Here, we conducted bioinformatic analysis and biological validation to investigate the
Publikováno v:
Cancer Letters. 497:165-177
Phospholipase A2 enzymes (PLA2s) comprise a superfamily that is generally divided into six subfamilies known as cytosolic PLA2s (cPLA2s), calcium-independent PLA2s (iPLA2s), secreted PLA2s (sPLA2s), lysosomal PLA2s, platelet-activating factor (PAF) a
Autor:
Zishuo Chen, Xiaoqing Jiang, Feiling Feng, Huizhen Wang, Mingjia Xiao, Yanxin Chang, Xiaoya Xu, Jun Zhou, Li Fugen, Dadong Zhang, Yan Li, Qingxiang Gao, Chuncui Huang
Publikováno v:
Translational Cancer Research
Background Gallbladder carcinoma (GBC) is one of the most lethal malignancies which do not have a targeted drug in the clinic. Patient-derived primary cell lines (PDCs) are useful in assessment of cancer complexity and heterogeneity, drug-sensitivity
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
The impact of antiviral therapy before tumorigenesis on microvascular invasion (MVI) of Chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) is still unknown. In this retrospective cohort study 3,276 HCC patients with early-stage who unde
Autor:
Yingcheng Yang, Kai Lu, Yanxin Chang, Jicheng Duan, Jiahe Yang, Kai Liu, Hu Liu, Feiling Feng, Chen Liu, Meng-Chao Wu
Publikováno v:
Journal of gastroenterology. 55(1)
Gallbladder carcinoma (GBC) is one of the most aggressive and lethal tumors, with extremely high metastatic activity and poor prognosis. Previously we have studied miRNAs that promote metastasis and progression of GBC, the aim of present study was to
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
The impact of antiviral therapy before tumorigenesis on microvascular invasion (MVI) of Chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) is still unknown. In this retrospective cohort study 3,276 HCC patients with early-stage who unde
Autor:
Liang Li, Lin Xu, Yingcheng Yang, Xian-ming Wang, Yanxin Chang, Caiyang Chen, Gao-Mi-Yang Liu, Jing Tang, Ruoyu Wang, Wentao Huang, Hongyang Wang, Wen Wen, Feng Jiang, Lei Chen
Publikováno v:
Cancer Research. 75:1470-1481
CYP3A5 is a cytochrome P450 protein that functions in the liver metabolism of many carcinogens and cancer drugs. However, it has not been thought to directly affect cancer progression. In this study, we challenge this perspective by demonstrating tha
Autor:
Meng-Chao Wu, Min-hong Li, Juan Li, Yanxin Chang, Dan-Dan Huang, Liang Hu, Rui-ying Zheng, Lei Chen, Ruo-yu Wang, QianQian Tu, Liang Li, He-ping Hu, Hongyang Wang
Publikováno v:
Acta Pharmacologica Sinica. 35:504-512
Free fatty acid-induced lipotoxicity plays a crucial role in the progression of nonalcoholic fatty liver disease (NAFLD). In the present study we investigated the effects of a high-fat diet and free fatty acids on the autophagic process in hepatocyte
Autor:
Miyang Liu-Gao, Yexiong Tan, Guangwen Cao, Baohua Zhang, Jin Gu, Dan Cao, Liang Li, Hengyu Li, Yingcheng Yang, Feng Jiang, Lin-Na Guo, Jing Tang, Wen Yang, Ruoyu Wang, Meng-Chao Wu, Lei Chen, Jing Fu, Yanxin Chang, Dingming Wu, Jianling Fan, Caiyang Chen, Hongyang Wang, Michael Q. Zhang
Publikováno v:
Gut. 64:156-167
Objective Liver tumour-initiating cells (T-ICs) are critical for hepatocarcinogenesis. However, the underlying mechanism regulating the function of liver T-ICs remains unclear. Methods Tissue microarrays containing 242 hepatocellular carcinoma (HCC)