Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Yanxi Han"'
Autor:
Duo Wang, Yaqing Liu, Yuanfeng Zhang, Qingwang Chen, Yanxi Han, Wanwan Hou, Cong Liu, Ying Yu, Ziyang Li, Ziqiang Li, Jiaxin Zhao, Leming Shi, Yuanting Zheng, Jinming Li, Rui Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Translating RNA-seq into clinical diagnostics requires ensuring the reliability and cross-laboratory consistency of detecting clinically relevant subtle differential expressions, such as those between different disease subtypes or stages. As
Externí odkaz:
https://doaj.org/article/ae2e7e53a9394d0a822c998df5bb0f2f
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Targeted panel-based tumor mutation burden (TMB) assays are widely employed to guide immunotherapy for patients with solid tumors. However, the accuracy and consistency of this method can be compromised due to the variability in technical de
Externí odkaz:
https://doaj.org/article/85ff6a7bd2ce40dba9fb8657bb1fc649
Autor:
Yu Ma, Jian Jiang, Yanxi Han, Yuqing Chen, Zhenli Diao, Tao Huang, Lei Feng, Lu Chang, Duo Wang, Yuanfeng Zhang, Jinming Li, Rui Zhang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Currently, DNA-based nucleic acid amplification tests (NAATs) and RNA-based NAATs are employed to detect reproductive tract infection (RTI) pathogens including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Ureaplasma urealyticu
Externí odkaz:
https://doaj.org/article/7648f08da16f43e0abd4774fc08b095c
Publikováno v:
Journal of Advanced Research, Vol 38, Iss , Pp 213-222 (2022)
Introduction: Metagenomic next-generation sequencing (mNGS) assay for detecting infectious agents is now in the stage of being translated into clinical practice. With no approved approaches or guidelines available, laboratories adopt customized mNGS
Externí odkaz:
https://doaj.org/article/392aafa4592847ae8102a25d633ad3ab
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed an enormous burden on the global public health system and has had disastrous socioeconomic consequences. Currently, single sampling tests, 20-in-1 pooling
Externí odkaz:
https://doaj.org/article/3a134687859842698b5c9a08340fc85b
Publikováno v:
International Journal of Infectious Diseases, Vol 111, Iss , Pp 233-241 (2021)
Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has had a significant impact on global public health systems, making nucleic acid detection an important tool in epidemic prevention and control. Detection kits based
Externí odkaz:
https://doaj.org/article/e60a3f89f66f4a549271651fe7432ecc
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Girdin, as an actin-binding protein, plays a major role in maintaining the stability of the actin skeleton structure and affects the growth, development, and migration of neurons. This study discusses the mechanism of Girdin in brain degeneration cau
Externí odkaz:
https://doaj.org/article/062407b44cf041cd8a06445f34c490aa
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
This study aimed to evaluate inter-laboratory classification concordance for copy number variants (CNVs) with a semiquantitative point-based scoring metric recommended by the American College of Medical Genetics and Genomics (ACMG) and Clinical Genom
Externí odkaz:
https://doaj.org/article/3c2a2eeaab0944e684953eb82dd14da3
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Exome sequencing has become an effective diagnostic method for Mendelian disorders. But the quality of services differs widely across laboratories in China, particularly in variant classification, even with the adoption of the ACMG guidelines. As an
Externí odkaz:
https://doaj.org/article/db9d7834ed0f46269db1c780d00147ad
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-6 (2017)
Abstract Background The early detection of type 1 diabetes (T1D) largely depends on a reliable approach to monitor β cell loss. An effective way to evaluate the decline of β cell mass would allow early preventative intervention to preserve insulin
Externí odkaz:
https://doaj.org/article/2c81e90b07ab484a990d6c87a427d26b