Lumican - derived peptides inhibit melanoma cell growth and migration.

Autor: Katarzyna Pietraszek, Stéphane Brézillon, Corinne Perreau, Maria Malicka-Błaszkiewicz, François-Xavier Maquart, Yanusz Wegrowski

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76232 (2013)

Lumican, a small leucine-rich proteoglycan of the extracellular matrix, presents potent anti-tumor properties. Previous works from our group showed that lumican inhibited melanoma cell migration and tumor growth in vitro and in vivo. Melanoma cells a

Externí odkaz: https://doaj.org/article/ae5ab7fe00754366943b9d0064a1254b

Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing

Autor: Gwenn Perrot, Nicolas Berthelemy, C. Garbar, Christine Jeanmaire, François-Xavier Maquart, Vincent Bardey, Isabelle Proult, Yanusz Wegrowski, Stéphane Brézillon, C. Colin-Pierre, Laurent Ramont, Louis Danoux, Solène Mine

Publikováno v: Experimental Gerontology
Experimental Gerontology, Elsevier, 2019, 126, pp.110693. ⟨10.1016/j.exger.2019.110693⟩

Background Glypicans (GPCs) are heparan sulfate cell membrane proteoglycans containing glycosylphosphatidylinositol (GPI) anchor. They play important role in cell behavior by activating/presenting numerous growth factors and cytokines. Objectives The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66db47d4a5694c847a6846c095885825
https://hal.univ-reims.fr/hal-02986599

Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity

Autor: Aurore Chatron-Colliet, Marta Stasiak, Shukti Chakravarti, Konstantina Karamanou, Joanna Boncela, François-Xavier Maquart, M. Anna Kowalska, Corinne Perreau, Isabelle Proult, Stéphane Brézillon, Yanusz Wegrowski, Patrycja Przygodzka

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0150226 (2016)
PLoS ONE
PLoS ONE, 2016, 11 (3), pp.e0150226. ⟨10.1371/journal.pone.0150226⟩

Lumican, a small leucine rich proteoglycan, inhibits MMP-14 activity and melanoma cell migration in vitro and in vivo. Snail triggers epithelial-mesenchymal transitions endowing epithelial cells with migratory and invasive properties during tumor pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff305318686bd9f5ef6b6b9dfdf3e3a
http://europepmc.org/articles/PMC4773148?pdf=render

Ultraviolet-B irradiation induces epidermal up-regulation of heparanase expression and activity

Autor: Solène Mine, Yanusz Wegrowski, Sandrine Kurdykowski, Eva Brabencova, Gilles Pauly, Vincent Bardey, Louis Danoux, Christine Jeanmaire, François-Xavier Maquart

Publikováno v: Journal of Photochemistry and Photobiology B: Biology
Journal of Photochemistry and Photobiology B: Biology, Elsevier, 2012, 106, pp.107-112

Heparan sulfate (HS) glycosaminoglycans are abundant components of basement membranes and cell surfaces where they are present associated with specific core-proteins to form proteoglycans, mainly perlecan, glypicans and syndecans. They play many role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24da4e69cf0c4995aab28ea1f422b8b
https://doi.org/10.1016/j.jphotobiol.2011.10.013

Ultraviolet-B Irradiation Induces Differential Regulations of Hyaluronidase Expression and Activity in Normal Human Keratinocytes

Autor: Vincent Bardey, François-Xavier Maquart, Eva Brabencova, Sandrine Kurdykowski, Solène Mine, Gilles Pauly, Christine Jeanmaire, Yanusz Wegrowski, Louis Danoux

Publikováno v: Photochemistry and Photobiology. 87:1105-1112

Skin aging is a complex process determined by genetic factors (intrinsic aging) and environmental factors (extrinsic aging). One of the most influential environmental factor is UV-B irradiation. Hyaluronic acid (HA) is an abundant component of skin e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8566fc0b92e546595a39658ca0789bd1
https://doi.org/10.1111/j.1751-1097.2011.00959.x