Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity.

Autor: Marta Stasiak, Joanna Boncela, Corinne Perreau, Konstantina Karamanou, Aurore Chatron-Colliet, Isabelle Proult, Patrycja Przygodzka, Shukti Chakravarti, François-Xavier Maquart, M Anna Kowalska, Yanusz Wegrowski, Stéphane Brézillon

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0150226 (2016)

Lumican, a small leucine rich proteoglycan, inhibits MMP-14 activity and melanoma cell migration in vitro and in vivo. Snail triggers epithelial-mesenchymal transitions endowing epithelial cells with migratory and invasive properties during tumor pro

Externí odkaz: https://doaj.org/article/265db50b725145cc80dae7173d7596d5

Effect of lumican on the migration of human mesenchymal stem cells and endothelial progenitor cells: involvement of matrix metalloproteinase-14.

Autor: Mariusz Malinowski, Katarzyna Pietraszek, Corinne Perreau, Mateusz Boguslawski, Véronique Decot, Jean-François Stoltz, Laurent Vallar, Jolanta Niewiarowska, Czeslaw Cierniewski, François-Xavier Maquart, Yanusz Wegrowski, Stéphane Brézillon

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50709 (2012)

Increasing number of evidence shows that soluble factors and extracellular matrix (ECM) components provide an optimal microenvironment controlling human bone marrow mesenchymal stem cell (MSC) functions. Successful in vivo administration of stem cell

Externí odkaz: https://doaj.org/article/e671b5211a9b487ca53b58c1760fdecf

Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins

Autor: Yanusz Wegrowski, Stéphane Brézillon, François-Xavier Maquart, Katarzyna Pietraszek

Publikováno v: FEBS Journal
FEBS Journal, Wiley, 2013, 280 (10), pp.2369-2381

Lumican is a member of the small leucine-rich proteoglycan family. It is present in numerous extracellular matrices of different tissues, such as muscle, cartilage, and cornea. In skin, lumican is present as a glycoprotein. It plays a critical role i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3015c75047766a9ec9743b3d93c7397
https://doi.org/10.1111/febs.12210

Ultraviolet-B irradiation induces epidermal up-regulation of heparanase expression and activity

Autor: Solène Mine, Yanusz Wegrowski, Sandrine Kurdykowski, Eva Brabencova, Gilles Pauly, Vincent Bardey, Louis Danoux, Christine Jeanmaire, François-Xavier Maquart

Publikováno v: Journal of Photochemistry and Photobiology B: Biology
Journal of Photochemistry and Photobiology B: Biology, Elsevier, 2012, 106, pp.107-112

Heparan sulfate (HS) glycosaminoglycans are abundant components of basement membranes and cell surfaces where they are present associated with specific core-proteins to form proteoglycans, mainly perlecan, glypicans and syndecans. They play many role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24da4e69cf0c4995aab28ea1f422b8b
https://doi.org/10.1016/j.jphotobiol.2011.10.013

Ultraviolet-B Irradiation Induces Differential Regulations of Hyaluronidase Expression and Activity in Normal Human Keratinocytes

Autor: Vincent Bardey, François-Xavier Maquart, Eva Brabencova, Sandrine Kurdykowski, Solène Mine, Gilles Pauly, Christine Jeanmaire, Yanusz Wegrowski, Louis Danoux

Publikováno v: Photochemistry and Photobiology. 87:1105-1112

Skin aging is a complex process determined by genetic factors (intrinsic aging) and environmental factors (extrinsic aging). One of the most influential environmental factor is UV-B irradiation. Hyaluronic acid (HA) is an abundant component of skin e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8566fc0b92e546595a39658ca0789bd1
https://doi.org/10.1111/j.1751-1097.2011.00959.x