Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yanshan Fang"'
Autor:
Wenkai Yue, Xue Deng, Zhao Wang, Mingsheng Jiang, Rirong Hu, Yongjia Duan, Qiangqiang Wang, Jihong Cui, Yanshan Fang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract TDP-43 is an important DNA/RNA-binding protein that is associated with age-related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD); however, its pathomechanism is not fully understood.
Externí odkaz:
https://doaj.org/article/f4b78073f17244e5837b263460df080f
Autor:
Haoyan Wang, Yixin Zhang, Kaixing Zeng, Jiali Qiang, Ye Cao, Yunxia Li, Yanshan Fang, Yaoyang Zhang, Yiyun Chen
Publikováno v:
JACS Au, Vol 1, Iss 7, Pp 1066-1075 (2021)
Externí odkaz:
https://doaj.org/article/12928db9b863482b89181164074a7a32
Autor:
Yichen Li, Jinge Gu, Chen Wang, Jiaojiao Hu, Shenqing Zhang, Cong Liu, Shengnan Zhang, Yanshan Fang, Dan Li
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104356- (2022)
Summary: Hsp70 is a key molecular chaperone in the protein quality control system to safeguard protein homeostasis in cells. Previous studies have shown that Hsp70 chaperones TDP-43, a pathogenic protein associated with amyotrophic lateral sclerosis
Externí odkaz:
https://doaj.org/article/c9dfc1ff6efa4224bc7e12d66fecf8c3
Autor:
Yunpeng Sun, Kun Zhao, Wencheng Xia, Guoqin Feng, Jinge Gu, Yeyang Ma, Xinrui Gui, Xia Zhang, Yanshan Fang, Bo Sun, Renxiao Wang, Cong Liu, Dan Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) shuttles between the nucleus and cytoplasm to regulate gene expression and RNA metabolism and its low complexity (LC) C-terminal domain facilitates liquid–liquid phase separation and amyloid aggr
Externí odkaz:
https://doaj.org/article/7fbc850f6f3e46a78b4dbc0a94ba0a02
Autor:
Kai Zhang, Qingyao Wang, Yiyao Liang, Yu Yan, Haiqiong Wang, Xu Cao, Bing Shan, Yaoyang Zhang, Ang Li, Yanshan Fang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Nerve injury induces profound and complex changes at molecular and cellular levels, leading to axonal self-destruction as well as immune and inflammatory responses that may further promote neurodegeneration. To better understand how neural injury cha
Externí odkaz:
https://doaj.org/article/f880b7d2f1bc4937b30d7fbcc3b365b6
Autor:
Xiaojuan Ma, Yi Zhu, Jinxia Lu, Jingfei Xie, Chong Li, Woo Shik Shin, Jiali Qiang, Jiaqi Liu, Shuai Dou, Yi Xiao, Chuchu Wang, Chunyu Jia, Houfang Long, Juntao Yang, Yanshan Fang, Lin Jiang, Yaoyang Zhang, Shengnan Zhang, Rong Grace Zhai, Cong Liu, Dan Li
Publikováno v:
eLife, Vol 9 (2020)
Tau hyper-phosphorylation and deposition into neurofibrillary tangles have been found in brains of patients with Alzheimer’s disease (AD) and other tauopathies. Molecular chaperones are involved in regulating the pathological aggregation of phospho
Externí odkaz:
https://doaj.org/article/7a6c38a74c5f4d10ba956531826059aa
Autor:
Yanshan Fang, Nancy M Bonini
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 2, Pp 173-175 (2015)
Externí odkaz:
https://doaj.org/article/253a65e0592944e6b4a41e383ddaba5e
Autor:
David S Garbe, Yanshan Fang, Xiangzhong Zheng, Mallory Sowcik, Rana Anjum, Steven P Gygi, Amita Sehgal
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003749 (2013)
Circadian rhythms in Drosophila rely on cyclic regulation of the period (per) and timeless (tim) clock genes. The molecular cycle requires rhythmic phosphorylation of PER and TIM proteins, which is mediated by several kinases and phosphatases such as
Externí odkaz:
https://doaj.org/article/61b5d0d5ac0f45b1af6e917e755c8e53
Publikováno v:
Annual Review of Genetics. 55:93-113
Significant advances have been made in recent years in identifying the genetic components of Wallerian degeneration, the process that brings the progressive destruction and removal of injured axons. It has now been accepted that Wallerian degeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69091754362471109e1f3e2a295f2a7
https://doi.org/10.1146/annurev-genet-071819-103917
https://doi.org/10.1146/annurev-genet-071819-103917
Autor:
Zeqing Wang, Zhuxia Li, Tianle Luan, Guizhong Cui, Shunpan Shu, Yiyao Liang, Jingshu Xiao, Kai Zhang, Wei Yu, Jihong Cui, Ang Li, Guangdun Peng, Yanshan Fang
While spinal cord injury (SCI) involves a complex cascade of cellular and pathological changes that last for months to years, the most dramatic and comprehensive molecular rewiring and multicellular re-organization occur in the first few days, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d5519a6be3566c8a4b6fec106557199
https://doi.org/10.1101/2022.10.07.511269
https://doi.org/10.1101/2022.10.07.511269
