Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yanshan, Cao"'
Publikováno v:
Chemical Research in Toxicology. 34:849-856
Idiosyncratic drug-induced liver injury (IDILI) is an idiosyncratic drug reaction that is specific to an individual and can lead to liver failure and even death. The mechanism of IDILI remains poorly understood, but most IDILI appears to be immune-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff5a9610f6240cba3840687e20219cf4
https://doi.org/10.1021/acs.chemrestox.0c00485
https://doi.org/10.1021/acs.chemrestox.0c00485
Publikováno v:
Toxicological Sciences
Trimethoprim (TMP)-induced skin rash and liver injury are likely to involve the formation of reactive metabolites. Analogous to nevirapine-induced skin rash, 1 possible reactive metabolite is the sulfate conjugate of α-hydroxyTMP, a metabolite of TM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecf8d7017aee16c918da98c1b290512
http://europepmc.org/articles/PMC7916736
http://europepmc.org/articles/PMC7916736
Autor:
Katsuhisa Kurogi, Yanshan Cao, Koshi Segawa, Yoichi Sakakibara, Masahito Suiko, Jack Uetrecht, Ming-Cheh Liu
Publikováno v:
Biochemical pharmacology. 204
Nevirapine (NVP) is an effective drug for the treatment of HIV infections, but its use is limited by a high incidence of severe skin rash and liver injury. 12-Hydroxynevirapine (12-OH-NVP) is the major metabolite of nevirapine. There is strong eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dd8b01e3520e0f8fed613392370f70
https://pubmed.ncbi.nlm.nih.gov/36084709
https://pubmed.ncbi.nlm.nih.gov/36084709
Autor:
Jeffrey T. Henderson, Christopher E. Rodgers, Andrew J. Elia, Shudi Huang, Andrea C Elia, Chesarahmia Dojo Soeandy, Yanshan Cao
Publikováno v:
Cellular and Molecular Neurobiology. 41:1727-1742
The primary forms of cell death seen in ischemic stroke are of two major types: a necrotic/necroptotic form, and an apoptotic form that is frequently seen in penumbral regions of injury. Typically apoptotic versus necroptotic programmed cell death is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32351e9d8df9edad7c799b1eae9c0c0d
https://doi.org/10.1007/s10571-020-00942-y
https://doi.org/10.1007/s10571-020-00942-y
Publikováno v:
Chemical research in toxicology. 34(3)
Idiosyncratic drug-induced liver injury (IDILI) is an idiosyncratic drug reaction that is specific to an individual and can lead to liver failure and even death. The mechanism of IDILI remains poorly understood, but most IDILI appears to be immune-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4f8a0181e179dad7af9c62ea4a3fb12
https://pubmed.ncbi.nlm.nih.gov/33617238
https://pubmed.ncbi.nlm.nih.gov/33617238
Autor:
Chesarahmia, Dojo Soeandy, Andrew J, Elia, Yanshan, Cao, Christopher, Rodgers, Shudi, Huang, Andrea C, Elia, Jeffrey T, Henderson
Publikováno v:
Cellular and molecular neurobiology. 41(8)
The primary forms of cell death seen in ischemic stroke are of two major types: a necrotic/necroptotic form, and an apoptotic form that is frequently seen in penumbral regions of injury. Typically apoptotic versus necroptotic programmed cell death is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a00d8194aa7a22895858e17276946ce6
https://pubmed.ncbi.nlm.nih.gov/32844322
https://pubmed.ncbi.nlm.nih.gov/32844322
Autor:
Yanshan Cao, Jack Uetrecht
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085eea951a624b991e13e0b5caf8ad93
https://doi.org/10.1016/j.dmpk.2018.09.086
https://doi.org/10.1016/j.dmpk.2018.09.086