Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yanru Xin"'
Autor:
Wenqi Li, Jing Hu, Cheng Chen, Xinyue Li, Honghua Zhang, Yanru Xin, Qingchang Tian, Shuling Wang
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 459-471 (2023)
Significant developments in cell therapy and biomaterial science have broadened the therapeutic landscape of tissue regeneration. Tissue damage is a complex biological process in which different types of cells play a specific role in repairing damage
Externí odkaz:
https://doaj.org/article/3d2adc312ddc41868f6e9f360b07be92
Autor:
Xiuxia Wang, Yuanhong Chen, Xiang Yang, Lianghui Cheng, Zhenyan He, Yanru Xin, Shan Huang, Fanling Meng, Peijing Zhang, Liang Luo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-11 (2022)
Abstract Ferroptosis is a recently-defined tumor suppression mechanism, but the sensitivity of many tumorigenic cells to ferroptosis is limited by their deficient expression of acyl-CoA synthetase long-chain family member 4 (ACSL4). Here, we report t
Externí odkaz:
https://doaj.org/article/0c6fd77914c24ba6aea002202cadbef5
Publikováno v:
Cancer Biology & Medicine, Vol 14, Iss 3, Pp 228-241 (2017)
The development of cancer nanotherapeutics has attracted great interest in the recent decade. Cancer nanotherapeutics have overcome several limitations of conventional therapies, such as nonspecific biodistribution, poor water solubility, and limited
Externí odkaz:
https://doaj.org/article/96e126af0bed489d9636019998336ee4
Publikováno v:
Nanoscale. 14:2802-2815
The misfolding and aggregation of human islet amyloid polypeptide (IAPP) into β-sheet-enriched amyloid fibrils is linked to type 2 diabetes. Antibodies are potent inhibitors of IAPP amyloidogenesis, but their preparation is usually complicated and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e3be0036892e88f07293f38efc1e03
https://doi.org/10.1039/d1nr08090c
https://doi.org/10.1039/d1nr08090c
Autor:
Xiang Yang, Zhenyan He, Peijing Zhang, Lianghui Cheng, Liang Luo, Shan Huang, Yanru Xin, Yuanhong Chen, Xiuxia Wang, Fanling Meng
Publikováno v:
Cell Death & Disease. 13
Ferroptosis is a recently-defined tumor suppression mechanism, but the sensitivity of many tumorigenic cells to ferroptosis is limited by their deficient expression of acyl-CoA synthetase long-chain family member 4 (ACSL4). Here, we report the discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fca553ec54989ee392de0d83853e3b
https://doi.org/10.1038/s41419-022-05462-9
https://doi.org/10.1038/s41419-022-05462-9
Autor:
Li Su, Huichuan Ke, Yujuan Cao, Liang Luo, Hui Liu, Yunhu Shang, Fanling Meng, Sheng Wang, Yuanda Huang, Yanru Xin, Xiangliang Yang, Haibo Jia, Sidan Tian
Publikováno v:
ACS nano. 15(8)
The development of inhibitors that can effectively mitigate the amyloidogenesis of human islet amyloid polypeptide (hIAPP), which is linked to type II diabetes, remains a great challenge. Oligotyrosines are intriguing candidates in that they can bloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea27d2c4ae5f9c0e832d41614f2429f
https://pubmed.ncbi.nlm.nih.gov/34293858
https://pubmed.ncbi.nlm.nih.gov/34293858
Publikováno v:
ACS applied materialsinterfaces. 13(13)
Photosensitizers that can generate reactive oxygen species (ROS) upon irradiation have emerged as promising agents for photodynamic degradation of toxic amyloid aggregates that are linked to many amyloidogenic diseases. However, due to the ultrastabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65213b4b03906fb399e75fb87733803f
https://pubmed.ncbi.nlm.nih.gov/33764749
https://pubmed.ncbi.nlm.nih.gov/33764749
Publikováno v:
ACS biomaterials scienceengineering. 5(2)
Misfolding and amyloid formation of human islet amyloid polypeptide (IAPP) are believed to be critical in the pathogenesis of type 2 diabetes. Inhibitors that can effectively prevent protein aggregation and fibrillation are considered as potential th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2530fe6e2e529307e5241fca9d942c7f
https://pubmed.ncbi.nlm.nih.gov/33405799
https://pubmed.ncbi.nlm.nih.gov/33405799
Publikováno v:
ACS Applied Materials & Interfaces. 10:31069-31079
Misfolding and aggregation of human islet amyloid polypeptide (hIAPP) into fibrils are important contributions to the pathology of type 2 diabetes. Developing effective inhibitors of protein aggregation and fibrillation has been considered a promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43c2445b2216d0bebb32f936b030d9e
https://doi.org/10.1021/acsami.8b11078
https://doi.org/10.1021/acsami.8b11078
Publikováno v:
Cancer Biology & Medicine
Cancer Biology & Medicine, Vol 14, Iss 3, Pp 228-241 (2017)
Cancer Biology & Medicine, Vol 14, Iss 3, Pp 228-241 (2017)
The development of cancer nanotherapeutics has attracted great interest in the recent decade. Cancer nanotherapeutics have overcome several limitations of conventional therapies, such as nonspecific biodistribution, poor water solubility, and limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d228e46a8f265e125006554934df9f22
http://europepmc.org/articles/PMC5570600
http://europepmc.org/articles/PMC5570600