Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Yanru Deng"'
Autor:
Xi Chen, Yifan Wang, Huiqiao Li, Yanru Deng, Charlise Giang, Anying Song, Yu’e Liu, Qiong A. Wang, Yi Zhu
Publikováno v:
Cells, Vol 13, Iss 15, p 1233 (2024)
Adipose tissue beiging refers to the process by which beige adipocytes emerge in classical white adipose tissue depots. Beige adipocytes dissipate chemical energy and secrete adipokines, such as classical brown adipocytes, to improve systemic metabol
Externí odkaz:
https://doaj.org/article/6bf52c8d6b444c76856a977136246f97
Autor:
Yingpeng Li, Xianxiu Kong, Xinhong Chu, Hui Fu, Xinchi Feng, Chengcheng Zhao, Yanru Deng, Jun Ge
Publikováno v:
Molecules, Vol 29, Iss 12, p 2836 (2024)
The malignancy of breast cancer poses a global challenge, with existing treatments often falling short of desired efficacy. Extensive research has underscored the effectiveness of targeting the metabolism of nicotinamide adenine dinucleotide (NAD), a
Externí odkaz:
https://doaj.org/article/05c26973c2af419f9a481cade9e83405
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
BRD4 inhibitors have demonstrated promising potential in cancer therapy. However, their therapeutic efficacy in breast cancer varies depending on the breast cancer subtype, particularly in the treatment of TNBC. In this study, we designed and synthes
Externí odkaz:
https://doaj.org/article/347cc9da2ebd4099ac0d990529363a33
Autor:
Xiang Cui, Zehong Huang, Shanshan Deng, Yunxia Zhang, Guoyin Li, Lining Wang, Yanru Deng, Changjing Wu
Publikováno v:
Molecules, Vol 29, Iss 2, p 315 (2024)
The phytochemical investigation of Cortex Mori Radicis led to the isolation and identification of a new prenylated benzofuranone (1) and four ring-opening derivatives (2–5) named albaphenol A–E, as well as nigranol A (6), together with ten 2-aryl
Externí odkaz:
https://doaj.org/article/46ecc27900d04773bfd6c94244ecd572
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Two undescribed butenolide derivatives, asperteretal J (1) and K (2), together with 13 known ones (3–15) were isolated from an endophytic fungus Aspergillus terreus SGP-1, the fermentation product of which exhibited selective inhibitory activity to
Externí odkaz:
https://doaj.org/article/2146690aba5e480a8c5f58d66df66d16
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Cyclin-dependent kinase 1 (CDK1) plays an indispensable role in the whole cell cycle. It has become a new target for cancer therapy. According to the binding mode of a pan-CDK inhibitor, flavopiridol with CDK1, and our previous work, a new series of
Externí odkaz:
https://doaj.org/article/2ed35f22a3df4d4eb7435e8b7736753a
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Berberine (BBR) is a plant derived quaternary benzylisoquinoline alkaloid, which has been widely used in traditional medicines for a long term. It possesses broad pharmacological effects and is widely applied in clinical. In recent years, the anti-tu
Externí odkaz:
https://doaj.org/article/eeb92066c2a84b1ba407b33dd001438a
Publikováno v:
Journal of Chemistry, Vol 2021 (2021)
Physalis alkekengi L. var. franchetii (PALF) is a traditional Chinese medicine, which is well known for its antimicrobial, anti-inflammatory, antipyretic, and expectorant properties. Its fruits and fruiting calyxes are used as dietary supplements and
Externí odkaz:
https://doaj.org/article/bcb3ec9de1ca41acbaef7bdd0a36e7cb
Publikováno v:
Journal of Chemistry, Vol 2020 (2020)
Flavonoids are important active components of traditional Chinese medicines (TCMs) because of their many biological activities. We studied the interaction between 17 polysaccharides and eight flavonoids via high-performance liquid chromatography (HPL
Externí odkaz:
https://doaj.org/article/49016b65ed9440fbb808c3c00a296d92
Autor:
Tuo Deng, Joey Liu, Yanru Deng, Laurie Minze, Xiang Xiao, Valerie Wright, Richeng Yu, Xian C. Li, Alecia Blaszczak, Stephen Bergin, David DiSilvestro, Ryan Judd, David Bradley, Michael Caligiuri, Christopher J. Lyon, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Obesity is associated with inflammation in adipose tissue, characterized by a shift in local T cell subsets. Here the authors show that loss of MHCII expression on adipocytes increases levels of immunosuppressive regulatory T cells in adipose tissue,
Externí odkaz:
https://doaj.org/article/f06d437e5dce45deabca2a777dc8a491