Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis

Autor: Shuang Zhao, Xin Tang, Zian Miao, Yurong Chen, Jiawei Cao, Tianyu Song, Daiting You, Yanqing Zhong, Zhe Lin, Dan Wang, Zhiguang Shi, Xinlong Tang, Dongjin Wang, Shaoliang Chen, Liansheng Wang, Aihua Gu, Feng Chen, Liping Xie, Zhengrong Huang, Hong Wang, Yong Ji

Publikováno v: Redox Biology, Vol 52, Iss , Pp 102290- (2022)

Endothelial dysfunction is the initial process of atherosclerosis. Heat shock protein 90 (Hsp90), as a molecular chaperone, plays a crucial role in various cardiovascular diseases. Hsp90 function is regulated by S-nitrosylation (SNO). However, the pr

Externí odkaz: https://doaj.org/article/5d6d3af2809c45e6bd18ccab8e9274a1

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

Autor: Ao Chen, Yidi Sun, Ying Lei, Chao Li, Sha Liao, Zhifeng Liang, Feng Lin, Nini Yuan, Mei Li, Kexin Wang, Meisong Yang, Shuzhen Zhang, Zhenkun Zhuang, Juan Meng, Qiong Song, Yong Zhang, Yuanfang Xu, Luman Cui, Lei Han, Hao Yang, Xing Sun, Tianyi Fei, Bichao Chen, Wenjiao Li, Baoqian Huangfu, Kailong Ma, Zhao Li, Yikun Lin, Zhen Liu, He Wang, Yanqing Zhong, Huifang Zhang, Qian Yu, Yaqian Wang, Zhiyong Zhu, Xing Liu, Jian Peng, Chuanyu Liu, Wei Chen, Yingjie An, Shihui Xia, Yanbing Lu, Mingli Wang, Xinxiang Song, Shuai Liu, Zhifeng Wang, Chun Gong, Xin Huang, Yue Yuan, Yun Zhao, Zhenhui Luo, Xing Tan, Jianfeng Liu, Mingyuan Zheng, Shengkang Li, Yaling Huang, Yan Hong, Zirui Huang, Min Li, Ruiyi Zhang, Mengmeng Jin, Yan Li, Hui Zhang, Suhong Sun, Yinqi Bai, Mengnan Cheng, Guohai Hu, Shiping Liu, Bo Wang, Bin Xiang, Shuting Li, Huanhuan Li, Mengni Chen, Shiwen Wang, Qi Zhang, Weibin Liu, Xin Liu, Qian Zhao, Michael Lisby, Jing Wang, Jiao Fang, Zhiyue Lu, Yun Lin, Qing Xie, Jie He, Huatai Xu, Wei Huang, Wu Wei, Huanming Yang, Yangang Sun, Muming Poo, Jian Wang, Yuxiang Li, Zhiming Shen, Longqi Liu, Zhiyong Liu, Xun Xu, Chengyu Li

Global profile of gene expression at single-cell resolution remains to be determined for primates. Using a recently developed technology (“Stereo-seq”), we have obtained a comprehensive single-cell spatial transcriptome map at the whole-brain lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91696bcb5917788d7802c32e8cf6eebc
https://doi.org/10.1101/2022.03.23.485448

Effects of glucocorticoids on the levels of serum tumor necrosis factor alpha and interleukin 6 in patients with rheumatoid arthritis

Autor: Jinwei, Luo, Yanqing, Zhong

Publikováno v: Am J Transl Res

Objective: The study was designed to explore the effects of glucocorticoid therapy on the levels of serum interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) in patients with rheumatoid arthritis (RA). Methods: Clinical information of 100 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8084749efdf2fe59098e792b27d1d7cc
https://pubmed.ncbi.nlm.nih.gov/34377267

A real-time object tracking and image stabilization system for photographing in vibration environment using OpenTLD algorithm

Autor: Yuxiang Hong, Dong Du, Jinle Zeng, Yanqing Zhong, Chang Shuhe, Zhenhua Quan

Publikováno v: ARSO

With the rapid development of computer vision technology, target tracking systems based on image processing is widely used in various fields. Aiming at the problem of image blurring while photographing in vibration environment, this paper proposed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d647aec89357efd3790a946553110821
https://doi.org/10.1109/arso.2016.7736271

[Increase expression of neurotrophins mRNA in peripheral blood of patients with allergic rhinitis]

Autor: Renhui, Chen, Hao, Wang, Yanqing, Zhong, Yiqun, Geng, Ciyan, Xu, Weibiao, Kang, Yulong, Lin

Publikováno v: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. 28(5)

To assess the expression of NGF, BDNF, NT-3 mRNA in the peripheral blood of patients with allergic rhinitis (AR). Meanwhile, to analysis whether the expression of NGF, BDNF, NT-3 mRNA correlate with the severity of rhinitis.This study is a group cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e3add9100d4950ce418c055cf34bdbe
https://pubmed.ncbi.nlm.nih.gov/25185284