Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yannis Gerakis"'
Autor:
Claudia Duran-Aniotz, Natalia Poblete, Catalina Rivera-Krstulovic, Álvaro O. Ardiles, Mei Li Díaz-Hung, Giovanni Tamburini, Carleen Mae P. Sabusap, Yannis Gerakis, Felipe Cabral-Miranda, Javier Diaz, Matias Fuentealba, Diego Arriagada, Ernesto Muñoz, Sandra Espinoza, Gabriela Martinez, Gabriel Quiroz, Pablo Sardi, Danilo B. Medinas, Darwin Contreras, Ricardo Piña, Mychael V. Lourenco, Felipe C. Ribeiro, Sergio T. Ferreira, Carlos Rozas, Bernardo Morales, Lars Plate, Christian Gonzalez-Billault, Adrian G. Palacios, Claudio Hetz
Publikováno v:
Molecular Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c98e87431ed56aa86b106853f2b384b
https://doi.org/10.1016/j.ymthe.2023.03.028
https://doi.org/10.1016/j.ymthe.2023.03.028
Autor:
Felipe Cabral‐Miranda, Giovanni Tamburini, Gabriela Martinez, Alvaro O Ardiles, Danilo B Medinas, Yannis Gerakis, Mei‐Li Diaz Hung, René Vidal, Matias Fuentealba, Tim Miedema, Claudia Duran‐Aniotz, Javier Diaz, Cristobal Ibaceta‐Gonzalez, Carleen M Sabusap, Francisca Bermedo‐Garcia, Paula Mujica, Stuart Adamson, Kaitlyn Vitangcol, Hernan Huerta, Xu Zhang, Tomohiro Nakamura, Sergio Pablo Sardi, Stuart A Lipton, Brian K Kennedy, Juan Pablo Henriquez, J Cesar Cárdenas, Lars Plate, Adrian G Palacios, Claudio Hetz
Publikováno v:
The EMBO Journal. 41
Aging is a major risk factor to develop neurodegenerative diseases and is associated with decreased buffering capacity of the proteostasis network. We investigated the significance of the unfolded protein response (UPR), a major signaling pathway act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474993c75fc394a4e5abf662a623e8f9
https://doi.org/10.15252/embj.2022111952
https://doi.org/10.15252/embj.2022111952
Autor:
Claudia Duran-Aniotz, Catalina Rivera-Krstulovic, Natalia Poblete, Álvaro O. Ardiles, Mei Li Díaz, Carleen Mae P. Sabusap, Yannis Gerakis, Felipe Cabral Miranda, Javier Diaz, Matias Fuentealba, Ernesto Muñoz, Sandra Espinoza, Gabriela Martinez, Gabriel Quiroz, Giovanni Tamburini, Danilo B. Medinas, Darwin Contreras, Ricardo Piña, Mychael V. Lourenco, Felipe C. Ribeiro, Sergio T. Ferreira, Carlos Rozas, Bernardo Morales, Lars Plate, Christian Gonzalez-Billault, Adrian G. Palacios, Claudio Hetz
Alteration in the buffering capacity of the proteostasis network is an emerging feature of Alzheimer’s disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is the main adaptive pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375ad74064acffde10be3a7c764e1cb4
https://doi.org/10.1101/2022.06.21.496869
https://doi.org/10.1101/2022.06.21.496869
Publikováno v:
Trends Cell Biol
Post-translational modifications are at the apex of cellular communication and eventually regulate every aspect of life. The identification of new post-translational modifiers is opening alternative avenues in understanding fundamental cell biology p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94936f2374c7b4d2ac2562ca17eb8154
https://doi.org/10.1016/j.tcb.2019.09.005
https://doi.org/10.1016/j.tcb.2019.09.005
Autor:
Claudio Hetz, Yannis Gerakis
Publikováno v:
Molecular Psychiatry. 24:474-478
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd112cf60533ebdd5ce2fa27e3c548bb
https://doi.org/10.1038/s41380-018-0343-7
https://doi.org/10.1038/s41380-018-0343-7
Autor:
Xu Zhang, Cristobal Ibaceta Ibaceta-Gonzalez, Stuart A. Lipton, Stuart S. Adamson, Claudio Hetz, Claudia Duran-Aniotz, Carleen Sabusap, Giovanni Tamburini, Hernan Huerta, Adrian G. Palacios, Kaitlyn Vitangcol, Tomohiro Nakamura, Tim Miedema, Francisca Bermedo, Danilo B. Medinas, S. Pablo Sardi, Felipe Cabral-Miranda, Yannis Gerakis, Alvaro O. Ardiles, Julio Matus, Juan Pablo Henríquez, Gabriela Martínez, Lars Plate, Brian K. Kennedy
Brain ageing is the main risk factor to develop dementia and neurodegenerative diseases, associated with a decay in the buffering capacity of the proteostasis network. We investigated the significance of the unfolded protein response (UPR), a major s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eaf1474df3730b09b4553264afe5af0
https://doi.org/10.21203/rs.3.rs-83658/v1
https://doi.org/10.21203/rs.3.rs-83658/v1
Autor:
Kaitlyn Vitangcol, Xu Zhang, Giovanni Tamburini, Gabriela Martínez, Yannis Gerakis, Lars Plate, Francisca Bermedo-Garcia, Tomohiro Nakamura, Alvaro Ardilles, Julio Cardenas Cardenas, S. Pablo Sardi, Danilo B. Medinas, Felipe Cabral Miranda, Adrian G. Palacios, Claudia Duran-Aniotz, Juan Pablo Henríquez, Cristobal Ibaceta, Stuart A. Lipton, Carleen Sabusap, Tim Miedema, Stuart S. Adamson, Brian K. Kennedy, Claudio Hetz, Hernan Huerta
Aging is the major risk factor for the development of dementia and neurodegenerative disorders, and the aging brain manifests severe deficits in buffering capacity by the proteostasis network. Accordingly, we investigated the significance of the unfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4b13d30da3d9174f42e0ab997d7c97
Autor:
Yannis Gerakis, Claudio Hetz
Publikováno v:
The FEBS Journal. 285:995-1011
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by synaptic dysfunction and accumulation of abnormal aggregates formed by amyloid-β peptides or phosphorylated tau proteins. Accumulating evidence suggests that altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226fe60697309e4bc63abbed2404b85c
https://doi.org/10.1111/febs.14332
https://doi.org/10.1111/febs.14332
Autor:
Claudio Hetz, Yannis Gerakis
Publikováno v:
Neurobiology of Aging. 63:162-164
Alterations in the buffering capacity of the proteostasis network are a salient feature of Alzheimer's disease, associated with the occurrence of chronic endoplasmic reticulum (ER) stress. To cope with ER stress, cells activate the unfolded protein r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d146982084758bbb18e60a3ee86f98a3
https://doi.org/10.1016/j.neurobiolaging.2017.09.012
https://doi.org/10.1016/j.neurobiolaging.2017.09.012
Autor:
Yannis, Gerakis, Claudio, Hetz
Publikováno v:
Molecular psychiatry. 24(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df8abf44617ed2e44ad9a2176aa30870
https://pubmed.ncbi.nlm.nih.gov/30617271
https://pubmed.ncbi.nlm.nih.gov/30617271