Výsledky vyhledávání - "Yannis Dalezios"

Akademický článek

Endonucleosis mediates internalization of cytoplasm into the nucleus

Autor: Ourania Galanopoulou, Evangelia C. Tachmatzidi, Elena Deligianni, Dimitris Botskaris, Kostas C. Nikolaou, Sofia Gargani, Yannis Dalezios, Georges Chalepakis, Iannis Talianidis

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract Setd8 regulates transcription elongation, mitotic DNA condensation, DNA damage response and replication licensing. Here we show that, in mitogen-stimulated liver-specific Setd8-KO mice, most of the hepatocytes are eliminated by necrosis but

Externí odkaz: https://doaj.org/article/7a63db086b584fafb014bb779aded084

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Akademický článek

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice

Autor: Emmanouela Kallergi, Akrivi-Dimitra Daskalaki, Angeliki Kolaxi, Come Camus, Evangelia Ioannou, Valentina Mercaldo, Per Haberkant, Frank Stein, Kyriaki Sidiropoulou, Yannis Dalezios, Mikhail M. Savitski, Claudia Bagni, Daniel Choquet, Eric Hosy, Vassiliki Nikoletopoulou

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)

Pruning dendritic spines requires autophagy. Here, the authors show that autophagy is required for long-term depression (LTD), a major form of synaptic plasticity. LTD induces the biogenesis of autophagic vesicles locally in dendrites to facilitate t

Externí odkaz: https://doaj.org/article/4c1ae7d8ce5140a2bdf18204c150e182

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Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

Autor: Vassiliki Nikoletopoulou, Maria Plataki, Mikhail M. Savitski, Yannis Dalezios, Kyriaki Sidiropoulou, Akrivi Dimitra Daskalaki, Frank Stein, Emmanuela Kallergi, Evangelia Ioannou, Per Haberkant, Angeliki Kolaxi

SummaryIn neurons, biogenesis of autophagic vesicles (AVs) is spatially confined to the axon tip under baseline conditions. However, it remains unknown whether their biogenesis can be induced in other neuronal compartments following synaptic activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83301c51198fc2b535ae10674caa524e

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Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat

Autor: Yannis Dalezios, Francesco Ferraguti, Ryuichi Shigemoto, Marco Capogna, Peter Somogyi, Naoki Kogo

Publikováno v: Kogo, N, Dalezios, Y, Capogna, M, Ferraguti, F, Shigemoto, R & Somogyi, P 2004, ' Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat ', The European journal of neuroscience, vol. 19, no. 10, pp. 2727-40 . https://doi.org/10.1111/j.0953-816X.2004.03394.x

The release of GABA in synapses is modulated by presynaptic metabotropic glutamate receptors (mGluRs). We tested whether GABA release to identified hippocampal neurons is influenced by group III mGluR activation using the agonist L-(+)-2-amino-4-phos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85919f3a95f9d44365dd61e823b151ac
https://ora.ox.ac.uk/objects/uuid:456fde59-fa6c-4f47-9625-3967a8b29607

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Different Fear States Engage Distinct Networks within the Intercalated Cell Clusters of the Amygdala

Autor: Nicolas Singewald, Francesco Ferraguti, Raffaella Geracitano, Daniela Busti, Mirosława Mańko, Marco Capogna, Yannis Dalezios, Nigel Whittle, Walter E. Kaufmann, Kurt Sätzler

Publikováno v: Busti, D, Geracitano, R, Whittle, N, Dalezios, Y, Mańko, M, Kaufmann, W, Sätzler, K, Singewald, N, Capogna, M & Ferraguti, F 2011, ' Different fear states engage distinct networks within the intercalated cell clusters of the amygdala ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 31, no. 13, pp. 5131-44 . https://doi.org/10.1523/JNEUROSCI.6100-10.2011

Although extinction-based therapies are among the most effective treatments for anxiety disorders, the neural bases of fear extinction remain still essentially unclear. Recent evidence suggests that the intercalated cell masses of the amygdala (ITCs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b270c13a0443cc272ac7b1a3c5faaa3
https://doi.org/10.1523/jneurosci.6100-10.2011

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Rhythmically Active Enkephalin-Expressing GABAergic Cells in the CA1 Area of the Hippocampus Project to the Subiculum and Preferentially Innervate Interneurons

Autor: Michèle Studer, Peter Somogyi, Pablo Fuentealba, Yannis Dalezios, Kathleen S. Rockland, Thomas Klausberger, Ryohei Tomioka, László F. Márton

Publikováno v: The Journal of Neuroscience. 28:10017-10022

Enkephalins (ENKs) are endogenous opioids that regulate synaptic excitability of GABAergic networks in the cerebral cortex. Using retrograde tracer injections in the subiculum, we identified a hippocampal population of ENK-expressing projection neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd6137d1f72eb45441e615e85f88145
https://doi.org/10.1523/jneurosci.2052-08.2008

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Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa

Autor: Yannis Dalezios, Petros Petrou, Evangelos Pavlakis, Georges Chalepakis

Publikováno v: Matrix Biology. 26:652-658

The Fraser syndrome protein Fras1 and the structurally related proteins Frem1, Frem2 and Frem3 comprise a novel family of extracellular matrix proteins implicated in the structural adhesion of the embryonic epidermis to the underlying mesenchyme. Fra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6eab144bde6c206d2133cc3d0549a4
https://doi.org/10.1016/j.matbio.2007.05.008

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Metabotropic Glutamate Receptor 8-Expressing Nerve Terminals Target Subsets of GABAergic Neurons in the Hippocampus

Autor: Ayae Kinoshita, Peter Szucs, Agnès Baude, P M Cobden, J. David B. Roberts, Yannis Dalezios, Peter Somogyi, Thomas Klausberger, Ryuichi Shigemoto, Francesco Ferraguti

Publikováno v: The Journal of Neuroscience. 25:10520-10536

Presynaptic metabotropic glutamate receptors (mGluRs) show a highly selective expression and subcellular location in nerve terminals modulating neurotransmitter release. We have demonstrated that alternatively spliced variants of mGluR8, mGluR8a and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d9b3c546d1cdf49b19fbd611c2d4a8
https://doi.org/10.1523/jneurosci.2547-05.2005

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Basement Membrane Distortions Impair Lung Lobation and Capillary Organization in the Mouse Model for Fraser Syndrome

Autor: Vassilis Galanopoulos, Georges Chalepakis, Petros Petrou, Yannis Dalezios, Evangelos Pavlakis

Publikováno v: Journal of Biological Chemistry. 280:10350-10356

Fras1 is a putative extracellular matrix protein that has been implicated in the structural adhesion of embryonic epidermis to dermis. Moreover, mutations in Fras1/FRAS1 have been associated with the mouse blebbed phenotype and the human rare genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910baa4f288e6240e9669850c2b8fbcd
https://doi.org/10.1074/jbc.m412368200

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