Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism

Autor: Juergen Geisel, Stefan Graeber, Yannick Rabagny, Rima Obeid, Hussain M. Awwad, Wolfgang Herrmann

Publikováno v: Obeid, R, Awwad, H M, Rabagny, Y, Graeber, S, Herrmann, W & Geisel, J 2016, ' Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism ', The American Journal of Clinical Nutrition, vol. 103, no. 3, pp. 703-11 . https://doi.org/10.3945/ajcn.115.121269

BACKGROUND: Elevated plasma concentrations of the gut bacteria choline metabolite trimethylamine N-oxide (TMAO) are associated with atherosclerosis. However, the determinants of TMAO in humans require additional assessment.OBJECTIVE: We examined card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f6228e7a86f4648cd161d0eaf41df1
https://doi.org/10.3945/ajcn.115.121269

Quantification of acetylcholine, choline, betaine, and dimethylglycine in human plasma and urine using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry

Autor: Susanne H. Kirsch, Wolfgang Herrmann, Yannick Rabagny, Rima Obeid

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 878(32)

Disorders in choline metabolism are related to disease conditions. We developed a stable-isotope dilution ultra performance liquid chromatography-mass spectrometry (UPLC-MS/MS) method for the simultaneous quantification of acetylcholine (ACh), betain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d754ae81150b37e2b1e96d28b9c1496b
https://pubmed.ncbi.nlm.nih.gov/21074502