Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yannick P. Ouedraogo"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The 7-nitroindolinyl family of caging chromophores has received much attention in the past two decades. However, its uncaging mechanism is still not clearly understood. In this study, we performed state-of-the-art density functional theory c
Externí odkaz:
https://doaj.org/article/1a0bf0a2d4034e888c7b8248f5387db3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
The 7-nitroindolinyl family of caging chromophores has received much attention in the past two decades. However, its uncaging mechanism is still not clearly understood. In this study, we performed state-of-the-art density functional theory calculatio
The 7-nitroindolinyl family of caging chromophores has received a lot of attention in the past two decades. However, it is not clear if they undergo cyclization or migration upon photo-uncaging to release the active compound. In this study, we perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e35863891499e8a550cb3472c5c145
https://doi.org/10.26434/chemrxiv.11991651.v1
https://doi.org/10.26434/chemrxiv.11991651.v1
Autor:
Attila Losonczy, Charitha Guruge, Nasri Nesnas, Richard L. Comitz, Jingxuan Ma, Yannick P. Ouedraogo
Publikováno v:
ACS Chemical Neuroscience. 9:2713-2721
Glutamate is an excitatory neurotransmitter that controls numerous pathways in the brain. Neuroscientists make use of photoremovable protecting groups, also known as cages, to release glutamate with precise spatial and temporal control. Various cage
Publikováno v:
Analytical Chemistry Research, Vol 3, Iss C, Pp 20-25 (2015)
Nitrated indolinyl photoprotecting groups are crucial tools extensively used in the study of neuronal signal transduction. Mononitrated photolabile protecting groups have been used effectively, however, recent advances in the introduction of a second
Autor:
Joshua Rokach, Shishir Chourey, Sylvie Gravel, William S. Powell, Qiuji Ye, Yannick P. Ouedraogo, Vivek Gore, Pranav Patel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:3385-3388
5-Oxo-ETE is the most potent eosinophil chemoattractant among lipid mediators. We have developed two 5-oxo-ETE receptor antagonists. In the course of the work, we have developed a procedure to selectively introduce a cis and trans double bond in an a
Autor:
Sylvie Gravel, Shishir Chourey, Joshua Rokach, Chintam Nagendra Reddy, Qiuji Ye, William S. Powell, Vivek Gore, Pranav Patel, Yannick P. Ouedraogo
Publikováno v:
ACS Medicinal Chemistry Letters. 5:815-819
5-Oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is formed by the oxidation of 5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-HETE), which is a major metabolite of enzymatic oxidation of arachidonic acid (AA). 5-Oxo-ETE is the most potent lipid ch
Autor:
Nasri Nesnas, Rudolf J. Wehmschulte, Mariana P. Torrente, Gloria Proni, Longchuan Huang, Yannick P. Ouedraogo, Ekaterina Chadwick
Publikováno v:
Chirality. 25:575-581
A two-step stereoselective preparation of a goldfish pheromone, 17α,20β-dihydroxy-4-pregnen-3-one, is reported from the readily available cortexolone in 64% overall yield. The (20S)-epimer was also synthesized in three steps from cortexolone with a
Autor:
Sylvie Gravel, Sashikala Sivendran, Chih-Tsung Chang, Yannick P. Ouedraogo, William S. Powell, Pranav Patel, Joshua Rokach, Namin Kang, Vivek Gore
Publikováno v:
Journal of Medicinal Chemistry. 56:3725-3732
5-Oxo-ETE is the most powerful eosinophil chemoattractant among lipid mediators. Eosinophil infiltration into the lungs of asthmatics may be responsible for the late phase of inflammatory asthma. We have designed and synthesized a 5-oxo-ETE receptor
Autor:
Yannick P, Ouedraogo, Longchuan, Huang, Mariana P, Torrente, Gloria, Proni, Ekaterina, Chadwick, Rudolf J, Wehmschulte, Nasri, Nesnas
Publikováno v:
Chirality. 25(9)
A two-step stereoselective preparation of a goldfish pheromone, 17α,20β-dihydroxy-4-pregnen-3-one, is reported from the readily available cortexolone in 64% overall yield. The (20S)-epimer was also synthesized in three steps from cortexolone with a