Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yannick Frey"'
Autor:
Yannick Frey, Cristiana Lungu, Florian Meyer, Franziskus Hauth, Daniel Hahn, Corinna Kersten, Vivien Heller, Mirita Franz-Wachtel, Boris Macek, Igor Barsukov, Monilola A. Olayioye
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110203- (2024)
Summary: Deleted in liver cancer 3 (DLC3) is a Rho GTPase-activating protein (RhoGAP) that plays a crucial role in maintaining adherens junction integrity and coordinating polarized vesicle transport by modulating Rho activity at the plasma membrane
Externí odkaz:
https://doaj.org/article/c2dd2d7e607b4fcbab13d79d9dba9f93
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The Rho GTPase activating protein Deleted in Liver Cancer 1 (DLC1) is frequently downregulated through genetic and epigenetic mechanisms in various malignancies, leading to aberrant Rho GTPase signaling and thus facilitating cancer progressi
Externí odkaz:
https://doaj.org/article/3a3ecf4d58c141179747416b4b4891cc
Publikováno v:
Scientific reports. 12(1)
The Rho GTPase activating protein Deleted in Liver Cancer 1 (DLC1) is frequently downregulated through genetic and epigenetic mechanisms in various malignancies, leading to aberrant Rho GTPase signaling and thus facilitating cancer progression. Here
Autor:
Katharina Bitschar, Patrick Weber, Antje Jensch, Yannick Frey, Monilola A. Olayioye, Simone Schmid, Angelika Hausser, Nicole Radde
Publikováno v:
Journal of Biological Chemistry. 293:14407-14416
Many newly synthesized cellular proteins pass through the Golgi complex from where secretory transport carriers sort them to the plasma membrane and the extracellular environment. The formation of these secretory carriers at the trans-Golgi network i
Autor:
Bettina Noll, David Benz, Peter L. Hordijk, Monilola A. Olayioye, Stephan A. Eisler, Yannick Frey, Simone Schmid, Manuel Lauinger, Florian Meyer
Publikováno v:
Journal of Cell Science, 132(11):jcs223172. Company of Biologists Ltd
Journal of cell science, 132(11). Company of Biologists Ltd
Noll, B, Benz, D, Frey, Y, Meyer, F, Lauinger, M, Eisler, S A, Schmid, S, Hordijk, P L & Olayioye, M A 2019, ' DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes ', Journal of Cell Science, vol. 132, no. 11, jcs223172 . https://doi.org/10.1242/jcs.223172
Journal of cell science, 132(11). Company of Biologists Ltd
Noll, B, Benz, D, Frey, Y, Meyer, F, Lauinger, M, Eisler, S A, Schmid, S, Hordijk, P L & Olayioye, M A 2019, ' DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes ', Journal of Cell Science, vol. 132, no. 11, jcs223172 . https://doi.org/10.1242/jcs.223172
Cancer cells degrade the extracellular matrix through actin-rich protrusions termed invadopodia. The formation of functional invadopodia requires polarized membrane trafficking driven by Rho GTPase-mediated cytoskeletal remodeling. We identify the Rh