Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yannick D. Benoit"'
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Abstract The histone methyltransferase G9a is well-documented for its implication in neoplastic growth. However, recent investigations have demonstrated a key involvement of this chromatin writer in maintaining the self-renewal and tumor-initiating c
Externí odkaz:
https://doaj.org/article/b8971e79981c4eedbbfe56b1ef193610
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101218- (2022)
Summary: Organoids can enable the study of solid tumors initiated from a single cancer stem cell (CSC) ex vivo. We describe a serial tumor organoid plating protocol using primary colorectal cancer (CRC) tissues as a rapid and cost-efficient approach
Externí odkaz:
https://doaj.org/article/13ffa8b9edfe485a911ba589a6d88828
Autor:
David Gagné, Yannick D. Benoit, Jean-François Groulx, Pierre H. Vachon, Jean-François Beaulieu
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background Fibronectin (FN) assembly into an insoluble fibrillar matrix is a crucial step in many cell responses to extracellular matrix (ECM) properties, especially with regards to the integrin-related mechanosensitive signaling pathway. We
Externí odkaz:
https://doaj.org/article/c11dc785d04d437a9a4e77ded5b1cf21
Autor:
Angelique N. Masibag, Christopher J. Bergin, Joshua R. Haebe, Aïcha Zouggar, Muhammad S. Shah, Tamara Sandouka, Amanda Mendes da Silva, François M. Desrochers, Aube Fournier-Morin, Yannick D. Benoit
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103442- (2021)
Summary: Cancer stem cells (CSCs) are documented to play a key role in tumorigenesis and therapy resistance. Despite significant progress in clinical oncology, CSC reservoirs remain elusive and difficult to eliminate. Reverse-turn peptidomimetics wer
Externí odkaz:
https://doaj.org/article/a4b364fa1b8740e1b8dceb3a7778dcb2
Autor:
Jong-Hee Lee, Sarah Laronde, Tony J. Collins, Zoya Shapovalova, Borko Tanasijevic, Jamie D. McNicol, Aline Fiebig-Comyn, Yannick D. Benoit, Jung Bok Lee, Ryan R. Mitchell, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 20-35 (2017)
Human pluripotent stem cells (hPSCs) have been reported in naive and primed states. However, the ability to generate mature cell types remains the imperative property for utility of hPSCs. Here, we reveal that the naive state enhances self-renewal wh
Externí odkaz:
https://doaj.org/article/632c81e24b1a4140a186435928fb0d4b
Autor:
François M. Desrochers, Yannick D. Benoit, Simon Y. Reilley, Christopher J. Bergin, Aïcha Zouggar, Angelique N. Masibag, Gautam Agrawal, Joshua R. Haebe
Publikováno v:
Oncogene
Colorectal tumors are hierarchically organized and governed by populations of self-renewing cancer stem cells, representing one of the deadliest types of cancers worldwide. Emergence of cancer stemness phenotype depends on epigenetic reprogramming, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9576d9c7fb9204c4f0c80db49ca72fe9
http://europepmc.org/articles/PMC7878189
http://europepmc.org/articles/PMC7878189
Publikováno v:
Gastroenterology. 162:S-706
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10cc6040cd12c90325b0287dc093168a
https://doi.org/10.1016/s0016-5085(22)61656-1
https://doi.org/10.1016/s0016-5085(22)61656-1
Autor:
Luciano da Fontoura Costa, Peter Van Dyken, Moises Freitas-Andrade, Christopher J. Bergin, Sylvain Baillet, Yannick D. Benoit, Christopher R.J. Kennedy, Baptiste Lacoste, Youlian Pan, Cesar H. Comin, Julie Ouellette, Ziying Liu, Cameron J Morse, Micaël Carrier, Sonia Leclerc, Marie-Ève Tremblay, Mirabelle Ho, Duncan J. Stewart, Dylan Burger, Melissa Yin, María Lacalle-Aurioles, William L. Stanford, Jean-Francois Thibodeau, Xavier Toussay, Qing Yan Liu
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled, vascular contributions to ASD remain elusive. Here, we investigated postnatal cerebrovascular development in the 16p11.2df/+ mouse model of 16p11.2 deletion ASD s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd9e5678d97ad9aa478e986a4be657e
https://doi.org/10.1038/s41593-020-0663-1
https://doi.org/10.1038/s41593-020-0663-1
Publikováno v:
Genes, Vol 11, Iss 616, p 616 (2020)
Genes
Genes
Recently, Kato et al. reported recurrent activating mutations in the SET domain of histone methyltransferase G9a, driving an oncogenic cascade in melanoma. The authors also reported correlations between G9a expression and the regulation of the canoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fd21e0c34daa76209c3e389df76781
https://www.mdpi.com/2073-4425/11/6/616
https://www.mdpi.com/2073-4425/11/6/616
Autor:
Christopher J. Bergin, Kinga Vojnits, Borko Tanasijevic, Zoya Shapovalova, Deanna P. Porras, Aïcha Zouggar, Meaghan Doyle, Luca Orlando, Angelique N. Masibag, Kalinka Koteva, Juan L. García-Rodríguez, Jagdish Suresh Patel, Jennifer Russell, Allison L. Boyd, Wenliang Wang, Ryan R. Mitchell, Tony J. Collins, Lili Aslostovar, Mickie Bhatia, Jakob Magolan, Gerard D. Wright, Yannick D. Benoit, Fanny L. Casado, Lakshmana K. Kinthada, Justin D. Lu, Sara N. Andres, Cody Caba
Publikováno v:
Cell Chem Biol
Summary Natural products (NPs) encompass a rich source of bioactive chemical entities. Here, we used human cancer stem cells (CSCs) in a chemical genomics campaign with NP chemical space to interrogate extracts from diverse strains of actinomycete fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc4b649220a9143bb55c542d4a9a1a0
https://doi.org/10.1016/j.chembiol.2021.04.014
https://doi.org/10.1016/j.chembiol.2021.04.014