Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yannick, Rose"'
Autor:
Stephane Ciblat, Ranga Reddy, Geoffrey A. McKay, Jerry Pelletier, Daniel M. Williams, Adel Rafai Far, Odette Belanger, Francis F. Arhin, Jing Liu, Dilip Dixit, Thomas R. Parr, Yannick Rose, Kelly S.E. Tanaka, Mohammed Dehbi, Evelyne Dietrich, Daniel Delorme, Ramakrishnan Srikumar, Yanick Lafontaine, Dario Lehoux, Philippe Gros, Greg Moeck
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:5812-5832
The RNA polymerase holoenzyme is a proven target for antibacterial agents. A high-throughput screening program based on this enzyme from Staphylococcus aureus had previously identified a 2-ureidothiophene-3-carboxylate as a low micromolar inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f17d3fa25f3945a6e85410ea13e86501
https://doi.org/10.1016/j.bmc.2006.05.035
https://doi.org/10.1016/j.bmc.2006.05.035
Autor:
Francis, Arhin, Odette, Bélanger, Stéphane, Ciblat, Mohammed, Dehbi, Daniel, Delorme, Evelyne, Dietrich, Dilip, Dixit, Yanick, Lafontaine, Dario, Lehoux, Jing, Liu, Geoffrey A, McKay, Greg, Moeck, Ranga, Reddy, Yannick, Rose, Ramakrishnan, Srikumar, Kelly S E, Tanaka, Daniel M, Williams, Philippe, Gros, Jerry, Pelletier, Thomas R, Parr, Adel Rafai, Far
Publikováno v:
Bioorganicmedicinal chemistry. 14(17)
The RNA polymerase holoenzyme is a proven target for antibacterial agents. A high-throughput screening program based on this enzyme from Staphylococcus aureus had previously identified a 2-ureidothiophene-3-carboxylate as a low micromolar inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98209a7c5a9bda3e658ad9cb8529f1f8
https://pubmed.ncbi.nlm.nih.gov/16759869
https://pubmed.ncbi.nlm.nih.gov/16759869
Autor:
Adel Rafai Far, Evelyne Dietrich, Hugo Poirier, Stephane Ciblat, Daniel Delorme, Adam Belley, Dario Lehoux, Geoffrey A. McKay, Yannick Rose, Ranga Reddy
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(4)
The preparation and biological evaluation of 5-substituted-6-hydroxy-2-(anilino)pyrimidinones as a new class of DNA polymerase IIIC inhibitors, required for the replication of chromosomal DNA in Gram-positive bacteria, are described. These new dGTP c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee27b40496e4e15015fddf390a277c16
https://pubmed.ncbi.nlm.nih.gov/16298129
https://pubmed.ncbi.nlm.nih.gov/16298129