Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yanneve Rolland"'
Autor:
Yanneve Rolland, Claude Godbout, Hui Ding, Alexandre Bramoullé, Michel O. Steinmetz, Rolf A. Brekken, Patrick G. Harran, Sami Chaaban, Thomas M. Wilkie, Ozhan Ocal, Natacha Olieric, Peter M. Siegel, Anne Roulston, Joseph C. Arezzo, Matthew G. Annis, Gary J. Brouhard, Cynthia Bernier, Mark A. Hancock, Cecilia Rocha, Anita Hall, Andrea E. Prota, Joseph Tcherkezian, Michal Wieczorek, George Zogopoulos, Gordon C. Shore
Publikováno v:
Science translational medicine, vol 8, iss 365
Microtubule-targeting agents (MTAs) are widely used anticancer agents, but toxicities such as neuropathy limit their clinical use. MTAs bind to and alter the stability of microtubules, causing cell death in mitosis. We describe DZ-2384, a preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38a6fb17c4299685199025dd72f9ddc
https://escholarship.org/uc/item/9dr6h535
https://escholarship.org/uc/item/9dr6h535
Autor:
Claude Godbout, Cecilia Rocha, Sami Chabaan, Ozhan Ocal, Yanneve Rolland, Anne Roulston, Gary J. Brouhard, Thomas M. Wilkie, Hui Ding, Gordon C. Shore, Cynthia Bernier, Rolf A. Brekken, Mark A. Hancock, Patrick G. Harran, Natacha Olieric, Andrea E. Prota, Joseph Tcherkezian, Michel O. Steinmetz, Michal Wieczorek
Publikováno v:
Molecular Cancer Therapeutics. 14:A188-A188
Microtubules are critical for cell proliferation, cellular invasion, migration and trafficking. As such, anti-mitotic tubulin binding agents continue to be a cornerstone of adjuvant chemotherapies across many different tumor indications. A major chal