Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yann-Yu Lu"'
Autor:
Shu Fu Lin, Li-Wei Teng, Ya-Chi Huang, Shyh-Fong Chen, Guan-Ru Huang, Chih-Lin Chang, Pi-Chen Hsu, Min-Sian Huang, Yu-Sheng Gao, Ya-Wen Chan, Jiann-Jyh Huang, Sheng-Chuan Yang, Bo-Han Jian, Yann-Yu Lu, Yu-Fen Chen, Tzu-Hao Lo, Shih-Hsien Chuang, Wen-Yun Hsueh, Po-Hsun Huang, Hsin-Yi Huang, Lien-Hsiang Chang, Win-Yin Wei, Ying-Chou Chen, Her-Sheng Lin, Shan-Yen Chou, Ta-Tung Yuan, Yu-Ting Chao, Ying-Shuan E. Lee, Yi-Feng Kao, Yu-Hsiang Lin, Jo-Chu Lin, Hung-Huang Liu, Shao-Yun Wang, Chin-Hung Lai, Shin-Yi Huang
Publikováno v:
Journal of Medicinal Chemistry. 64:1435-1453
In this paper, we present a copper(I)-catalyzed nitrile-addition/N-arylation ring-closure cascade for the synthesis of 5,11-dihydro-6H-indolo[3,2-c]quinolin-6-ones from 2-(2-bromophenyl)-N-(2-cyanophenyl)acetamides. Using CuBr and t-BuONa in dimethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fcb962b8cc2da85f8b630161defbab0
https://doi.org/10.1021/acs.jmedchem.0c00727
https://doi.org/10.1021/acs.jmedchem.0c00727
Autor:
Wen-Yun, Hsueh, Ying-Shuan E, Lee, Min-Sian, Huang, Chin-Hung, Lai, Yu-Sheng, Gao, Jo-Chu, Lin, Yu-Fen, Chen, Chih-Lin, Chang, Shan-Yen, Chou, Shyh-Fong, Chen, Yann-Yu, Lu, Lien-Hsiang, Chang, Shu Fu, Lin, Yu-Hsiang, Lin, Pi-Chen, Hsu, Win-Yin, Wei, Ya-Chi, Huang, Yi-Feng, Kao, Li-Wei, Teng, Hung-Huang, Liu, Ying-Chou, Chen, Ta-Tung, Yuan, Ya-Wen, Chan, Po-Hsun, Huang, Yu-Ting, Chao, Shin-Yi, Huang, Bo-Han, Jian, Hsin-Yi, Huang, Sheng-Chuan, Yang, Tzu-Hao, Lo, Guan-Ru, Huang, Shao-Yun, Wang, Her-Sheng, Lin, Shih-Hsien, Chuang, Jiann-Jyh, Huang
Publikováno v:
Journal of medicinal chemistry. 64(3)
In this paper, we present a copper(I)-catalyzed nitrile-addition/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f6c10c7f95ae0e1e8f3936e79865440
https://pubmed.ncbi.nlm.nih.gov/33492141
https://pubmed.ncbi.nlm.nih.gov/33492141
Autor:
Yu-Wen Tseng, Yann-Yu Lu, Mann-Yan Kuo, Chu-Bin Liao, Shian-Yi Chiou, Chia Wei Liu, Ying-Shuan Lee, Her Sheng Lin, Shao-Zheng Pen, Win Yin Wei
Publikováno v:
Cancer Research. 77:134-134
The Hedgehog (Hh) signaling pathway is a critical regulator of embryonic patterning, and aberrant Hh pathway activation has been implicated in a diverse spectrum of cancers. Therefore, components of the Shh pathway (such as Shh, SMO, and GLI1/2) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb69950bd82bcd2bf8c8a8a6745e183
https://doi.org/10.1158/1538-7445.am2017-134
https://doi.org/10.1158/1538-7445.am2017-134
Publikováno v:
Tetrahedron Letters. 40:3419-3422
A number ofN-acylalkylenediamines were synthesized in high yields byin situ monoamidation of car☐ylic acids with diamines. The amidation reactions were carried out simply by heating the substrates at 110 °C for 5–24 h in the presence of HMDS. HM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d0498c2387ce61519e93a8114c2dea
https://doi.org/10.1016/s0040-4039(99)00505-5
https://doi.org/10.1016/s0040-4039(99)00505-5
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2be1b41afd8eaeeb94a48941b384852d
https://doi.org/10.1002/chin.199928087
https://doi.org/10.1002/chin.199928087
Autor:
Win-Yin Wei, Ping-Kuei Tsai, Yann-Yu Lu, Huei-Yu Yang, Chu-Bin Liao, Pao-Chiung Hong, Hung-Yi Hsu, Shih-Jan Chiang, Tzu-Yun Lai, Li Jung Chen
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(17)
A series of selenophene derivatives 3 were synthesized as potential CHK1 inhibitors. The effects of substitution on the 4'- or 5'-position of selenophene moiety and shifting the hydroxyl group position on C6- phenolic ring of oxindole were explored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dee702f7bf9213eb2ba8c69d31581d
https://pubmed.ncbi.nlm.nih.gov/20674356
https://pubmed.ncbi.nlm.nih.gov/20674356