Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yann W. Yap"'
Autor:
Christos Symeonides, Kristina Vacy, Sarah Thomson, Sam Tanner, Hui Kheng Chua, Shilpi Dixit, Toby Mansell, Martin O’Hely, Boris Novakovic, Julie B. Herbstman, Shuang Wang, Jia Guo, Jessalynn Chia, Nhi Thao Tran, Sang Eun Hwang, Kara Britt, Feng Chen, Tae Hwan Kim, Christopher A. Reid, Anthony El-Bitar, Gabriel B. Bernasochi, Lea M. Durham Delbridge, Vincent R. Harley, Yann W. Yap, Deborah Dewey, Chloe J. Love, David Burgner, Mimi L. K. Tang, Peter D. Sly, Richard Saffery, Jochen F. Mueller, Nicole Rinehart, Bruce Tonge, Peter Vuillermin, the BIS Investigator Group, Anne-Louise Ponsonby, Wah Chin Boon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Male sex, early life chemical exposure and the brain aromatase enzyme have been implicated in autism spectrum disorder (ASD). In the Barwon Infant Study birth cohort (n = 1074), higher prenatal maternal bisphenol A (BPA) levels are associate
Externí odkaz:
https://doaj.org/article/61103e53974f40858070213fe5e84473
Autor:
Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Dietary protein dilution, where protein is reduced and replaced by other nutrient sources without caloric restriction, promotes metabolic health via the hepatokine Fgf21. Here, the authors show that essential amino acids threonine and tryptophan are
Externí odkaz:
https://doaj.org/article/36856bb21e41464a998b62244a235694
Autor:
Katherine Roberts-Thomson, Ludovico Maggi, Susanne Hille, Annika Zota, Yuqin Wu, Kathrin V. Schmidt, Michelle A. Keske, Yann W. Yap, Young H Lee, Thomas Sharkie, Andrea Y. Chan, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Ryan D. Russell, Stephan Herzig, Patricia M. Rusu, Oliver J. Müller, Matthias Blüher, Adam J. Rose, Jonas Schumacher
Publikováno v:
Nature metabolism. 3(3)
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Autor:
Annika Zota, Matthias Blüher, Ludovico Maggi, Susanne Hille, Oliver J. Müller, Yann W. Yap, Adam J. Rose, Young H Lee, Stephan Herzig, Kathrin V. Schmidt, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Andrea Y. Chan, Patricia M. Rusu, Jonas Schumacher, Thomas Sharkie
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492b8e07f2d20d5871f511aa3f7ea592
https://doi.org/10.1101/2020.05.25.115709
https://doi.org/10.1101/2020.05.25.115709
Autor:
Stefan Bröer, Christopher K. Barlow, Cheng Huang, Stephen J. Simpson, Darren J. Creek, Dieter Schmoll, Matthew D.W. Piper, Andrea Y. Chan, Samantha M. Solon-Biet, Bente Kiens, Oliver J. Müller, Yann W. Yap, Adam J. Rose, Barbara C Fam, Bruce A. Morgan, Mathias Heikenwalder, Andreas Jungmann, Patricia M. Rusu, Ralf B. Schittenhelm, Sofianos Andrikopoulos
Publikováno v:
Yap, Y W, Rusu, P M, Chan, A Y, Fam, B C, Jungmann, A, Solon-Biet, S M, Barlow, C K, Creek, D J, Huang, C, Schittenhelm, R B, Morgan, B, Schmoll, D, Kiens, B, Piper, M D W, Heikenwälder, M, Simpson, S J, Bröer, S, Andrikopoulos, S, Müller, O J & Rose, A J 2020, ' Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution ', Nature Communications, vol. 11, no. 1, 2894 . https://doi.org/10.1038/s41467-020-16568-z
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this response remain elusive. Here, by mimicking amino acid (AA) supply from a casein-based diet, we demonstrate that restriction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294484612c08d31e43d4f4a8d0080aa1
https://curis.ku.dk/portal/da/publications/restriction-of-essential-amino-acids-dictates-the-systemic-metabolic-response-to-dietary-protein-dilution(e8d27972-1dda-47ed-b3fe-10a2460ee39b).html
https://curis.ku.dk/portal/da/publications/restriction-of-essential-amino-acids-dictates-the-systemic-metabolic-response-to-dietary-protein-dilution(e8d27972-1dda-47ed-b3fe-10a2460ee39b).html
Autor:
Barbara C. Fam, Christopher K. Barlow, Patricia M. Rusu, Samantha M. Solon-Biet, Cheng Huang, Dieter Schmoll, Stefan Bröer, Bruce A. Morgan, Matthew D.W. Piper, Andreas Jungmann, Ralf B. Schittenhelm, Mathias Heikenwalder, Darren J. Creek, Adam J. Rose, Stephen J. Simpson, Andrea Y. Chan, Oliver J. Müller, Bente Kiens, Yann W. Yap, Sofianos Andrikopoulos
Dietary protein dilution (DPD) promotes metabolic remodelling and health but the precise nutritional components driving this response remain elusive. Here we demonstrate that dietary amino acids (AA) are sufficient and necessary to drive the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7b6bcb9e61e03d8c3db9b39d411858
Autor:
Nam Sang Cheung, Sharon La Fontaine, Yann W. Yap, Susan M. Ackland, Zhiguang Xiao, Stephanie Materia, Michael A. Cater, Kamil Wolyniec
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 27(4)
Glutaredoxin1 (GRX1) is a glutathione (GSH)-dependent thiol oxidoreductase. The GRX1/GSH system is important for the protection of proteins from oxidative damage and in the regulation of protein function. Previously we demonstrated that GRX1/GSH regu