Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yann Senechal"'
Autor:
Yann Senechal, Francois Natt, Peter H. Kelly, Matthias Staufenbiel, Christoph Wiessner, Kumlesh K. Dev, Laetitia Prut, Daniel Hoyer
Publikováno v:
Brain Research. 1243:124-133
Genetic abnormalities in amyloid precursor protein (APP) are associated with Down's syndrome and familial Alzheimer's disease where hallmark plaques contain A beta peptides derived from APP. Both APP and its derivatives are implicated in neurodegener
Publikováno v:
Behavioural Brain Research. 186:126-132
Amyloid precursor protein (APP) is involved in the pathogenesis of Alzheimer's disease (AD), but its role in cognition has been relatively little studied. APP knockout (KO) animals have been described previously and show deficits in grip strength, re
Publikováno v:
Journal of Neurochemistry. 102:1928-1940
The cleavage-product of amyloid precursor protein (APP) constitutes the core component of plaques found in the brains of Alzheimer's disease (AD) patients. APP is ubiquitously expressed and its precise physiological functions remain unclear. This pro
Publikováno v:
Journal of neurochemistry. 102(6)
The cleavage-product of amyloid precursor protein (APP) constitutes the core component of plaques found in the brains of Alzheimer's disease (AD) patients. APP is ubiquitously expressed and its precise physiological functions remain unclear. This pro
Publikováno v:
Neuro-degenerative diseases. 3(3)
The amyloid precursor protein (APP) is a widely expressed transmembrane protein that is cleaved to generate Aβ peptides in the central nervous system and is a key player in the pathogenesis of Alzheimer’s disease. The precise biological functions
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
Yann Senechal, Maribel Osinde, Florence Clavaguera, Andre Schade, Natacha Stoehr, San Pun, Hermann Putten, Matthias Staufenbiel, Markus Tolnay, Karl-Heinz Wiederhold, Kumlesh K. Dev
Publikováno v:
Alzheimer's & Dementia. 2