Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yann Nouët"'
Autor:
Elite Possik, Zahra Jalali, Yann Nouët, Ming Yan, Marie-Claude Gingras, Kathrin Schmeisser, Lorena Panaite, Fanny Dupuy, Dmitri Kharitidi, Laëtitia Chotard, Russell G Jones, David H Hall, Arnim Pause
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004273 (2014)
Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-b
Externí odkaz:
https://doaj.org/article/ef48d48370b1463d827a541d13d5f7ae
Autor:
Charlotte Labalette, Yann Nouët, Florence Levillayer, Sabine Colnot, Ju Chen, Valere Claude, Michel Huerre, Christine Perret, Marie-Annick Buendia, Yu Wei
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10371 (2010)
BACKGROUND: The four and a half LIM-only protein 2 (FHL2) is capable of shuttling between focal adhesion and nucleus where it signals through direct interaction with a number of proteins including beta-catenin. Although FHL2 activation has been found
Externí odkaz:
https://doaj.org/article/f00a7229ed1f4d32bfd0bdd3c5b828b8
Autor:
Charlotte Labalette, Yann Nouët, Florence Levillayer, Carolina Armengol, Claire-Angélique Renard, Guillaume Soubigou, Tian Xia, Marie-Annick Buendia, Yu Wei
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3761 (2008)
BACKGROUND: Four and a half LIM-only protein 2 (FHL2) has been implicated in multiple signaling pathways that regulate cell growth and tissue homeostasis. We reported previously that FHL2 regulates cyclin D1 expression and that immortalized FHL2-null
Externí odkaz:
https://doaj.org/article/21b31204e8624d13a8fa210a32dc192c
Autor:
Grégory Jouvion, Jennifer Dahan, Yann Nouët, Anne-Marie Cassard-Doulcier, Varun Khanna, Yu Wei, Thierry Tordjmann, Minou Adib-Conquy, Catherine Werts, Martine Fanton d'Andon, Florence Levillayer, Tian Xia, Marie-Annick Buendia, Ju Chen
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, American Society for Microbiology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, American Society for Microbiology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
International audience; Transforming growth factor β1 (TGF-β1) is a master cytokine in many biological processes, including tissue homeostasis, epithelial-to-mesenchymal transition, and wound repair. Here, we report that four and a half LIM-only pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bfb2239ac2147d7b2763213df83801
https://hal-pasteur.archives-ouvertes.fr/pasteur-02572332/file/LIM_only_protein_FHL2_2017_Dahan.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02572332/file/LIM_only_protein_FHL2_2017_Dahan.pdf
Autor:
Elite Possik, Yann Nouët, Marie-Claude Gingras, Fanny Dupuy, Ming Yan, Andrew R. Tee, Barry J. Coull, Sylvie Sabourin, Dmitri Kharitidi, Laëtitia Chotard, Rachael S. Preston, Russell G. Jones, Anders Bondo Dydensborg, Maurice A.M. van Steensel, Elaine A. Dunlop, Miriam A.F. Kamps, David Mark Davies, Taren Roughead, Arnim Pause, Brandon Faubert, Zahra Jalali
Publikováno v:
Journal of Clinical Investigation, 124(6), 2640-2650. American Society for Clinical Investigation
The Warburg effect is a tumorigenic metabolic adaptation process characterized by augmented aerobic glycolysis, which enhances cellular bioenergetics. In normal cells, energy homeostasis is controlled by AMPK; however, its role in cancer is not under
Autor:
Valérie Chénard, Chadi Zakaria, Tommy Alain, Ola Larsson, Simon-Pierre Gravel, Meztli Arguello, Masahiro Morita, Julie St-Pierre, Daina Avizonis, Liang Zheng, Eyal Gottlieb, Yann Nouët, Shannon McLaughlan, Valentina Gandin, Arnim Pause, Nahum Sonenberg, Ivan Topisirovic, Michael Pollak, Kristina Sikström
Publikováno v:
Cell Metabolism. 18(5):698-711
SummarymRNA translation is thought to be the most energy-consuming process in the cell. Translation and energy metabolism are dysregulated in a variety of diseases including cancer, diabetes, and heart disease. However, the mechanisms that coordinate
The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis
Autor:
Thierry Tordjmann, Yu Wei, Florence Levillayer, Stefano Cairo, Agnès Ribeiro, Sabine Colnot, Jeanne Tran Van Nhieu, Christine Perret, Grégory Jouvion, Francina Langa Vives, Michel Huerre, Boris Julien, Charlotte Labalette, Marie-Annick Buendia, Jennifer Dahan, Yann Nouët
Publikováno v:
Journal of Hepatology. 57:1029-1036
Background & Aims The four and a half LIM-only protein 2 (FHL2) is upregulated in diverse pathological conditions. Here, we analyzed the effects of FHL2 overexpression in the liver of FHL2 transgenic mice ( Apo-FHL2 ). Methods We first examined cell
Autor:
Kathrin Schmeisser, Lorena Panaite, David H. Hall, Fanny Dupuy, Yann Nouët, Dmitri Kharitidi, Elite Possik, Arnim Pause, Ming Yan, Laëtitia Chotard, Marie-Claude Gingras, Russell G. Jones, Zahra Jalali
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004273 (2014)
PLoS Genetics
PLoS Genetics
Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-b
Autor:
Jennifer Dahan, Grégory Jouvion, Lauriane Remy, Minou Adib-Conquy, Yann Nouët, Yu Wei, Anne-Marie Cassard-Doulcier, Stefano Cairo, Catherine Werts, Fany Blanc, Mustapha Si-Tahar, Ali Tebbi, Florence Levillayer, Ju Chen, Marie-Annick Buendia, Thierry Tordjmann
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2013, 33 (16), pp.3299-308. ⟨10.1128/MCB.00105-13⟩
Molecular and Cellular Biology, 2013, 33 (16), pp.3299-308. ⟨10.1128/MCB.00105-13⟩
Molecular and Cellular Biology, American Society for Microbiology, 2013, 33 (16), pp.3299-308. ⟨10.1128/MCB.00105-13⟩
Molecular and Cellular Biology, 2013, 33 (16), pp.3299-308. ⟨10.1128/MCB.00105-13⟩
International audience; Four-and-a-half LIM-only protein 2 (FHL2) is an important mediator in many signaling pathways. In this study, we analyzed the functions of FHL2 in nuclear factor κB (NF-κB) signaling in the liver. We show that FHL2 enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99cbf4883ec156f5ac4bbf4bd0a6c07
https://hal-univ-tours.archives-ouvertes.fr/hal-01118323
https://hal-univ-tours.archives-ouvertes.fr/hal-01118323
Autor:
Valere Claude, Marie-Annick Buendia, Florence Levillayer, Yu Wei, Yann Nouët, Sabine Colnot, Christine Perret, Ju Chen, Michel Huerre, Charlotte Labalette
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 4, p e10371 (2010)
PLoS ONE, Vol 5, Iss 4, p e10371 (2010)
BACKGROUND: The four and a half LIM-only protein 2 (FHL2) is capable of shuttling between focal adhesion and nucleus where it signals through direct interaction with a number of proteins including beta-catenin. Although FHL2 activation has been found