Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Yann Cheli"'
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon-Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan-Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2262-2267 (2024)
Externí odkaz:
https://doaj.org/article/4674eb9ca9f241b4a3996ff03dc79709
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-18 (2023)
Abstract Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome‐wide CRISPR‐Cas9 knockout screen, which revealed the LKB1‐SIK2 module in restraining uveal melanoma tumor
Externí odkaz:
https://doaj.org/article/1a3e75bad0684eebb8afbad93d505cd9
Autor:
Yann Cheli, Meri K. Tulic, Najla El Hachem, Nicolas Nottet, Arnaud Jacquel, Maeva Gesson, Thomas Strub, Karine Bille, Alexandra Picard-Gauci, Henri Montaudié, Guillaume E. Beranger, Thierry Passeron, Pierre Close, Corine Bertolotto, Robert Ballotti
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-5 (2021)
Abstract Resistances to immunotherapies remains a major hurdle towards a cure for melanoma in numerous patients. An increase in the mesenchymal phenotype and a loss of differentiation have been clearly associated with resistance to targeted therapies
Externí odkaz:
https://doaj.org/article/a109a58f73fa4ac585009c1946fc3fba
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract The clinical benefit of immune checkpoint inhibitory therapy (ICT) in advanced melanomas is limited by primary and acquired resistance. The molecular determinants of the resistance have been extensively studied, but these discoveries have no
Externí odkaz:
https://doaj.org/article/e356ec7b9fdf481db44e3867ff78144c
Autor:
Meri K. Tulic, Elisa Cavazza, Yann Cheli, Arnaud Jacquel, Carmelo Luci, Nathalie Cardot-Leccia, Hanene Hadhiri-Bzioueche, Patricia Abbe, Maéva Gesson, Laura Sormani, Claire Regazzetti, Guillaume E. Beranger, Cedric Lereverend, Caroline Pons, Abdallah Khemis, Robert Ballotti, Corine Bertolotto, Stéphane Rocchi, Thierry Passeron
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Tissue signals that prime autoreactive T cells at the onset of autoimmunity remain enigmatic. Here the authors show NK and ILC1 cells are increased in vitiligo patients, and induce melanocyte apoptosis via CXCR3B, which in turn leads to increased pri
Externí odkaz:
https://doaj.org/article/7ccace62b4554630a57bcf27df328dfb
Autor:
Yann Cheli, Meri K. Tulic, Najla El Hachem, Nicolas Nottet, Arnaud Jacquel, Maeva Gesson, Thomas Strub, Karine Bille, Alexandra Picard-Gauci, Henri Montaudié, Guillaume E. Beranger, Thierry Passeron, Pierre Close, Corine Bertolotto, Robert Ballotti
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/046931caca0a4d15a0880c5b9c1c5cee
Autor:
Giuseppina Claps, Yann Cheli, Tongwu Zhang, Marzia Scortegagna, Eric Lau, Hyungsoo Kim, Jianfei Qi, Jian-Liang Li, Brian James, Andreas Dzung, Mitchell P. Levesque, Reinhard Dummer, Nicholas K. Hayward, Marcus Bosenberg, Kevin M. Brown, Ze’ev A. Ronai
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1884-1892 (2016)
Melanoma is one of the most lethal cutaneous malignancies, characterized by chemoresistance and a striking propensity to metastasize. The transcription factor ATF2 elicits oncogenic activities in melanoma, and its inhibition attenuates melanoma devel
Externí odkaz:
https://doaj.org/article/3850dc004e8748c790379ebd4ad2af6d
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55094 (2013)
We have engineered a transgenic mouse on a C57BL/6 background that bears a floxed Itga2 gene. The crossing of this mouse strain to transgenic mice expressing Cre recombinase driven by the megakaryocyte (MK)-specific Pf4 promoter permits the condition
Externí odkaz:
https://doaj.org/article/c9f4b98311de41c1aafd3b468cb9b9ed
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8743 (2010)
We have identified a cytosine-adenosine (CA) repeat length polymorphism in the 5'-regulatory region of the human integrin alpha2 gene ITGA2 that begins at -605. Our objective was to establish the contribution of this polymorphism to the regulation of
Externí odkaz:
https://doaj.org/article/3877c385d80d462b9c801a5c78f333fc
Autor:
Corine Bertolotto, Robert Ballotti, Philippe Bahadoran, Gilles Ponzio, Paul Hofman, Véronique Hofman, Agnès Loubat, Karine Bille, Laurent Beuret, Caroline Bonet, Mickaël Ohanna, Yann Cheli, Sandy Giuliano
Supplementary Figure 9 from Microphthalmia-Associated Transcription Factor Controls the DNA Damage Response and a Lineage-Specific Senescence Program in Melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89af5b5368297492457eb190da1d60d9
https://doi.org/10.1158/0008-5472.22385730
https://doi.org/10.1158/0008-5472.22385730