Výsledky vyhledávání - "Yann Château"

Application of machine learning methods to guide patient management by predicting the risk of malignancy of Bethesda III-V thyroid nodules

Autor: Grégoire D’Andréa, Jocelyn Gal, Loïc Mandine, Olivier Dassonville, Clair Vandersteen, Nicolas Guevara, Laurent Castillo, Gilles Poissonnet, Dorian Culié, Roxane Elaldi, Jérôme Sarini, Anne Decotte, Claire Renaud, Sébastien Vergez, Renaud Schiappa, Emmanuel Chamorey, Yann Château, Alexandre Bozec

Publikováno v: European Journal of Endocrinology. 188:249-257

ObjectiveIndeterminate thyroid nodules (ITN) are common and often lead to (sometimes unnecessary) diagnostic surgery. We aimed to evaluate the performance of two machine learning methods (ML), based on routinely available features to predict the risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7801e71a9a3b69ed823b5ce8720b851e
https://doi.org/10.1093/ejendo/lvad017

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Therapeutic strategies, oncologic and swallowing outcomes and their predictive factors in patients with locally advanced hypopharyngeal cancer

Autor: Pierre Mattei, Brice Thamphya, Emmanuel Chamorey, Boris Scheller, Yann Château, Olivier Dassonville, Gilles Poissonnet, Dorian Culié, Pierre-Henri Koulmann, Raphaël Hechema, Anne Sudaka, Esma Saada, Karen Benezery, François Demard, Roxanne Elaldi, Alexandre Bozec

Publikováno v: European Archives of Oto-Rhino-Laryngology. 279:3629-3637

Hypopharyngeal cancer (HC) is an aggressive and life-threatening malignancy that requires a complex multimodal treatment. The aims of the present study were to analyze, in locally advanced HC patients, the oncologic and swallowing outcomes and their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c2b492d0732ddab0253c726b4e32b5
https://doi.org/10.1007/s00405-021-07196-4

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How to select candidates for microvascular head and neck reconstruction in the elderly? Predictive factors of postoperative outcomes

Autor: Grégoire D'Andrea, Raphaël Hechema, Emmanuel Chamorey, François Demard, Roxanne Elaldi, D. Culié, Jocelyn Gal, Yann Château, Pierre-Henri Koulmann, Gilles Poissonnet, Alexandre Bozec, Boris Scheller, Olivier Dassonville

Publikováno v: Surgical oncology. 34

The proportion of elderly patients with head and neck cancer is increasing. However, predictive factors of postoperative outcomes are insufficiently explored in this population. In this study, we aimed to determine predictive factors of postoperative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4498500960408ed262e5f14aa93a8da
https://pubmed.ncbi.nlm.nih.gov/32891324

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Robotic Stereotactic Boost in Early Breast Cancer, a Phase 2 Trial

Autor: Johan Levy, Pierre-Yves Bondiau, Juliette Haudebourg, Claire Chapellier, Jocelyn Gal, Juliette Thariat, Emmanuel Barranger, Shakeel Sumodhee, Yann Château, Maeva Maurin, Jean-Marc Ferrero, A. Gérard, Adel Courdi

Publikováno v: International Journal of Radiation Oncology-Biology-Physics
International Journal of Radiation Oncology-Biology-Physics, Elsevier, 2019, 103, pp.374-380. ⟨10.1016/j.ijrobp.2018.09.020⟩

Purpose To evaluate the feasibility and toxicity of a single-fraction 8-Gy stereotactic boost after whole-breast irradiation in early breast cancer. The primary aim of this phase 2 study was to evaluate cutaneous breast toxicity using National Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e146ccd128206b9b4d627b40b2fee4c
https://hal.archives-ouvertes.fr/hal-03486853

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Multicenter prospective micro-costing study evaluating mandibular free-flap reconstruction

Autor: Jocelyn Gal, Yann Château, Renaud Schiappa, Morbize Julieron, Marie-Helene Orlanducci, Emmanuel Chamorey, Bernard Devauchelle, Olivier Dassonville, Jérôme Sarini, Jacques Yachouh, Gilles Poissonnet, Yann Mallet, Marie-Yolande Louis, Alexandre Bozec, Gilles Dolivet, Emile Reyt, Pierre Breton

Publikováno v: European Archives of Oto-Rhino-Laryngology
European Archives of Oto-Rhino-Laryngology, Springer Verlag, 2017, 274 (2), pp.1103-1111. ⟨10.1007/s00405-016-4360-3⟩
European Archives of Oto-Rhino-Laryngology, 2017, 274 (2), pp.1103-1111. ⟨10.1007/s00405-016-4360-3⟩

International audience; Free-flap mandibular reconstruction is a highly specialized procedure associated with severe complications necessitating re-interventions and re-hospitalizations. This surgery is expensive in terms of health workers' time, equ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dd1e88b630d7ba3063a3205db130d1
https://hal.umontpellier.fr/hal-01807130

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New advances in DPYD genotype and risk of severe toxicity under capecitabine

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (5), pp.e0175998. ⟨10.1371/journal.pone.0175998⟩
PLoS ONE, Public Library of Science, 2017, 12 (5), pp.e0175998. 〈10.1371/journal.pone.0175998〉
PLoS ONE, 2017, 12 (5), pp.e0175998. ⟨10.1371/journal.pone.0175998⟩
PLoS ONE, Vol 12, Iss 5, p e0175998 (2017)
PLoS ONE, 12(5). Public Library of Science

International audience; Background: Deficiency in dihydropyrimidine dehydrogenase (DPD) enzyme is the main cause of severe and lethal fluoropyrimidine-related toxicity. Various approaches have been developed for DPD-deficiency screening, including DP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4684337b9f9ca84d09883437f02322
https://hal.archives-ouvertes.fr/hal-01780001/file/journal.pone.0175998.pdf

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Akademický článek

Survival analysis of patient groups defined by unsupervised machine learning clustering methods based on patient metabolomic data.

Autor: Caroline Bailleux, David Chardin, Jean-Marie Guigonis, Jean-Marc Ferrero, Yann Chateau, Olivier Humbert, Thierry Pourcher, Jocelyn Gal

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5136-5143 (2023)

Purpose: Meta-analyses failed to accurately identify patients with non-metastatic breast cancer who are likely to benefit from chemotherapy, and metabolomics could provide new answers. In our previous published work, patients were clustered using fiv

Externí odkaz: https://doaj.org/article/816f939c016a42129efa98d1890845fc

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A clinical pharmacokinetic analysis of tegafur-uracil (UFT) plus leucovorin given in a new twice-daily oral administration schedule

Autor: Jaafar Bennouna, Erick Gamelin, E. Francois, Gérard Milano, Marie-Christine Etienne-Grimaldi, Nicole Renée, Jean-Yves Douillard, Jean-Michel Cardot, Yann Château

Publikováno v: Clinical pharmacokinetics. 46(11)

Tegafur is an oral fluorouracil prodrug used in the treatment of colorectal cancer. The aim of this phase II, crossover, bioequivalence study was to compare the pharmacokinetics (primary objective) and tolerability (secondary objective) of tegafur-ur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25592bfc97aead0c17a4692a6454a2b
https://pubmed.ncbi.nlm.nih.gov/17922560

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