Evaluation and optimization of novel extraction algorithms for the automatic detection of atrial activations recorded within the pulmonary veins during atrial fibrillation

Autor: Yann Prudat, Adrian Luca, Sasan Yazdani, Nicolas Derval, Pierre Jaïs, Laurent Roten, Benjamin Berte, Etienne Pruvot, Jean-Marc Vesin, Patrizio Pascale

Publikováno v: BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract Background and objective The automated detection of atrial activations (AAs) recorded from intracardiac electrograms (IEGMs) during atrial fibrillation (AF) is challenging considering their various amplitudes, morphologies and cycle length.

Externí odkaz: https://doaj.org/article/7390516d395e445cb1b944a5baf71597

Stochastic pacing reveals the propensity to cardiac action potential alternans and uncovers its underlying dynamics

Autor: Jan P. Kucera, James N. Weiss, Marina Angelini, Yann Prudat, Riccardo Olcese, Enno de Lange, Alan Garfinkel, Roshni V. Madhvani, Nils P. Borgstom, Hrayr S. Karagueuzian

Publikováno v: The Journal of Physiology. 594:2537-2553

Key points Beat-to-beat alternation (alternans) of the cardiac action potential duration is known to precipitate life-threatening arrhythmias and can be driven by the kinetics of voltage-gated membrane currents or by instabilities in intracellular ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a06004ffce0dcca373fcd8e3b5728ea4
https://doi.org/10.1113/jp271573

Nonlinear behaviour of conduction and block in cardiac tissue with heterogeneous expression of connexin 43

Autor: Jan P. Kucera, Yann Prudat

Publikováno v: Journal of Molecular and Cellular Cardiology

Altered gap junctional coupling potentiates slow conduction and arrhythmias. To better understand how heterogeneous connexin expression affects conduction at the cellular scale, we investigated conduction in tissue consisting of two cardiomyocyte pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe2cb313886b6823f731e1db5415d2f
https://doi.org/10.1016/j.yjmcc.2014.07.019

Adaptive tracking of EEG oscillations

Autor: Micah M. Murray, Yann Prudat, Cédric Duchêne, Jérôme Van Zaen, Laurent Uldry, Jean-Marc Vesin, Reto Meuli

Publikováno v: JOURNAL OF NEUROSCIENCE METHODS

Neuronal oscillations are an important aspect of EEG recordings. These oscillations are supposed to be involved in several cognitive mechanisms. For instance, oscillatory activity is considered a key component for the top-down control of perception.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62161c789caa69b159a371c93a3d2c0f

Slow conduction in mixed cultured strands of primary ventricular cells and stem cell-derived cardiomyocytes

Autor: Nina D. Ullrich, Irene C. Marcu, Jan P. Kucera, Yann Prudat, Michela Azzarito

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 3 (2015)
Kucera, Jan; Prudat, Yann; Marcu, Irene Cristina; Azzarito, Michela; Ullrich, Nina (2015). Slow conduction in mixed cultured strands of primary ventricular cells and stem cell-derived cardiomyocytes. Frontiers in cell and developmental biology, 3, p. 58. Frontiers 10.3389/fcell.2015.00058
Frontiers in cell and developmental biology
Frontiers in Cell and Developmental Biology

Modern concepts for the treatment of myocardial diseases focus on novel cell therapeutic strategies involving stem cell-derived cardiomyocytes (SCMs). However, functional integration of SCMs requires similar electrophysiological properties as primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd5021f085a5dfe2be4ad1f4d4e6f42
http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00058/full