Výsledky vyhledávání - "Yanming F. Wang"

Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury

Autor: Dennis Huszar, Victoria Fairchild-Huntress, Qing Fang, Judy H. Dunmore, James R. Tonra, Gary X. Yu, Hong Zhou, Yanming F. Wang, Lakshmi S. Amaravadi, Yang Pan, Sulpicio G. Soriano

Publikováno v: Journal of Neuroimmunology. 125:59-65

Fractalkine (FKN), also known as neurotactin, is a CX(3)C chemokine that exists in both secreted and neuronal membrane-bound forms and is upregulated during brain inflammation. There is accumulating evidence that FKN induces chemotaxis by binding to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a107441c41ccde3eb0013d3ea1e440d6
https://doi.org/10.1016/s0165-5728(02)00033-4

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P- and E-selectin-deficient mice are susceptible to cerebral ischemia–reperfusion injury

Autor: Paul S. Frenette, Denisa D. Wagner, Yanming F. Wang, Sulpicio G. Soriano

Publikováno v: Brain Research. 835:360-364

We examined brain sections from P- and E-selectin-deficient mice (−/−) and their nontransgenic littermates (+/+) after focal cerebral ischemia and reperfusion (I/R) tissue injury. There was no difference in the subsequent infarct volume after 3 h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523cfdc30d3d43a7c4953d40991f361e
https://doi.org/10.1016/s0006-8993(99)01637-6

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Mice Deficient in Mac-1 (CD11b/CD18) Are Less Susceptible to Cerebral Ischemia/Reperfusion Injury

Autor: Yanming F. Wang, Matthew P. Frosch, Tanya N. Mayadas, Angela Coxon, Sulpicio G. Soriano, Stuart A. Lipton, Paul R. Hickey

Publikováno v: Stroke. 30:134-139

Background and Purpose —Macrophage-1 antigen (Mac-1) (CD11b/CD18), a leukocyte β2 integrin, facilitates neutrophil adhesion, transendothelial migration, phagocytosis, and respiratory burst, all of which may mediate reperfusion-induced injury to is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b890b593ff51fa2dd77198686953183
https://doi.org/10.1161/01.str.30.1.134

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ICAM-1 dependent pathway is not involved in the development of neuronal apoptosis after transient focal cerebral ischemia

Autor: Sulpicio G. Soriano, Pieter Dikkes, Paul R. Hickey, Jose-Carlos Gutierrez-Ramos, Yanming F. Wang, Stuart A. Lipton

Publikováno v: Brain Research. 780:337-341

We examined brain sections from ICAM-1 deficient mice (−/−) and their nontransgenic littermates (+/+) after focal cerebral ischemia and reperfusion (I/R) for the presence of apoptosis. Despite the reduction in necrosis, the −/− mice had apopt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbec7ecd11327b69da3d35400fd8f545
https://doi.org/10.1016/s0006-8993(97)01298-5

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Enhanced neuronal death from focal ischemia in AMPA-receptor transgenic mice

Autor: Adriana Nemes, Dean Le, Nobuki Nakanishi, Yanming F. Wang, Saumya Das, Toshihiro Yoshizawa, Yasnory F. Sasaki, Stuart A. Lipton, Mari A. Takasu, Pieter Dikkes, Monica Mendelsohn

Publikováno v: Molecular Brain Research. 52:235-241

Excitatory amino acid (EAA) receptors play an important role in neuronal cell death in acute cerebral ischemia. Blocking the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of EAA receptor has been shown to reduce cell death in gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff651cb9b24d3bc5c4ca36461d04be3
https://doi.org/10.1016/s0169-328x(97)00261-1

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

Autor: Sidney Strickland, Philip E. Stieg, Yanming F. Wang, Sulpicio G. Soriano, Stuart A. Lipton, Stella E. Tsirka

Publikováno v: Nature medicine. 4(2)

Intravenous tissue plasminogen activator (tPA) is used to treat acute stroke because of its thrombolytic activity and its ability to restore circulation to the brain. However, this protease also promotes neurodegeneration after intracerebral injectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257b867cde4d5ab723f3ed8d8a533049
https://pubmed.ncbi.nlm.nih.gov/9461181

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Cerebrospinal fluid may mediate CNS ischemic injury

Autor: Shunli He, Yanming F. Wang, Sulpicio G. Soriano, Judith K. Gwathmey, Yanguang Wang, Guorong Zhang

Publikováno v: Cerebrospinal Fluid Research
Cerebrospinal Fluid Research, Vol 2, Iss 1, p 7 (2005)

Background The central nervous system (CNS) is extremely vulnerable to ischemic injury. The details underlying this susceptibility are not completely understood. Since the CNS is surrounded by cerebrospinal fluid (CSF) that contains a low concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7576c33c974b34e2bc14388fd0d42d35
http://europepmc.org/articles/PMC1253519

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