Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yanmin Yao"'
Publikováno v:
2022 10th International Conference on Agro-geoinformatics (Agro-Geoinformatics).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff3413376e314ad82328698847edab4
https://doi.org/10.1109/agro-geoinformatics55649.2022.9859004
https://doi.org/10.1109/agro-geoinformatics55649.2022.9859004
Autor:
Bhairavi Tolani, Anna Celli, Yanmin Yao, Yong Zi Tan, Richard Fetter, Christina R. Liem, Adam J. de Smith, Thamiya Vasanthakumar, Paola Bisignano, Adam D. Cotton, Ian B. Seiple, John L. Rubinstein, Marco Jost, Jonathan S. Weissman
Publikováno v:
Nature biotechnology, vol 40, iss 12
Mutations in Ras family proteins are implicated in 33% of human cancers, but direct pharmacological inhibition of Ras mutants remains challenging. As an alternative to direct inhibition, we screened for sensitivities in Ras-mutant cells and discovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a71129bb71ed4aab46b2badda735d5
https://pubmed.ncbi.nlm.nih.gov/35879364
https://pubmed.ncbi.nlm.nih.gov/35879364
Autor:
Yanmin Yao, Anna Celli, Jonathan S. Weissman, Christina R Liem, Thamiya Vasanthakumar, Richard D. Fetter, Bhairavi Tolani, Paola Bisignano, Marco Jost, Yong Zi Tan, John L. Rubinstein, Ian B. Seiple, Adam J. de Smith
Mutations in the Ras family of oncogenes are implicated in 33% of human cancers, making Ras an intensely pursued target in drug discovery. As an alternative to direct pharmacological inhibition of Ras, we looked for sensitivities in RAS mutant cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12da45d4be8d9bcf358a44a5ff5af0a2
https://doi.org/10.1101/2020.12.23.423300
https://doi.org/10.1101/2020.12.23.423300
Publikováno v:
J Am Chem Soc
Journal of the American Chemical Society, vol 142, iss 35
Journal of the American Chemical Society, vol 142, iss 35
Lankacidins are a class of polyketide natural products isolated from Streptomyces spp. that show promising antimicrobial activity. Owing to their complex molecular architectures and chemical instability, structural assignment and derivatization of la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9af74d32098de8a6bd798b2f6d9362
https://europepmc.org/articles/PMC8193914/
https://europepmc.org/articles/PMC8193914/
Publikováno v:
Angewandte Chemie. 130:13739-13742
Lankacidins are a group of polyketide natural products with activity against several strains of Gram-positive bacteria. We developed a route to stereochemically diverse variants of 2,18-seco-lankacidinol B and found that the stereochemical assignment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9f39993685d29148079f09a56d4808
https://doi.org/10.1002/ange.201808612
https://doi.org/10.1002/ange.201808612
Publikováno v:
The Journal of Organic Chemistry. 83:5825-5828
Concise total syntheses of (-)-(1 R,6 S,7 S,10 R)-hydroxycadinan-3-en-5-one (1), (+)-(1 R,5 S,6 R,7 S,10 R)-cadinan-3-ene-1,5-diol (2), and (+)-(1 R,5 S,6 R,7 S,10 R)-cadinan-4(11)-ene-1,5-diol (3), three cadinane sesquiterpenes sharing identical tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db780fc1b1214bb482fefbafe49bba00
https://doi.org/10.1021/acs.joc.8b00505
https://doi.org/10.1021/acs.joc.8b00505
Publikováno v:
Tetrahedron. 73:4538-4544
We report concise asymmetric total syntheses of tetracyclic marine alkaloids (+)-agelastatin A and (+)-agelastatin B using a cationic cyclization-based approach, which features straightforward transformations with cost-effective chemicals and reagent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f64902c50de812d510a0fa8c0fd1b5b
https://doi.org/10.1016/j.tet.2017.06.009
https://doi.org/10.1016/j.tet.2017.06.009
Publikováno v:
Organic letters. 21(9)
A synthetically challenging tetracyclic tertiary amine framework in the Daphniphyllum alkaloid daphenylline was established in a six-step sequence featuring an intermolecular Diels-Alder cycloaddition/oxidative aromatization sequence. The utilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545f8eeb0fc91a161e3245d66b989977
https://pubmed.ncbi.nlm.nih.gov/31008614
https://pubmed.ncbi.nlm.nih.gov/31008614
Publikováno v:
Agro-Geoinformatics
Soil moisture content (SMC) is the important information for the crop land irrigation management and drought warning. The study of SMC quantitative inversion based on hyperspectral remote sensing technology has become the hot spot. Because of using s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b05c5451c09b98d16f3ec0a74a4e2d7
https://doi.org/10.1109/agro-geoinformatics.2018.8476086
https://doi.org/10.1109/agro-geoinformatics.2018.8476086
Publikováno v:
Chinese Journal of Eco-Agriculture. 22:277-283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980dd785b94f00db2a229bb251e096d4
https://doi.org/10.3724/sp.j.1011.2014.30983
https://doi.org/10.3724/sp.j.1011.2014.30983