Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Yanlu, Xiong"'
Autor:
Yahui Tian, Shaowei Xin, Zitong Wan, Honghong Dong, Lu Liu, Zhenzhen Fan, Tian Li, Fujun Peng, Yanlu Xiong, Yong Han
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101978- (2024)
Objective: This study aimed to investigate TCF19′s role in lung cancer development, specifically its involvement in the RAF/MEK/ERK signaling pathway. Methods: Lung cancer tissue analysis revealed significant TCF19 overexpression. In vitro experime
Externí odkaz:
https://doaj.org/article/712544e779784a008dc7ae102386543a
Autor:
Yingtong Wu, Yinggang Che, Yong Zhang, Yanlu Xiong, Chen Shu, Jun Jiang, Gaozhi Li, Lin Guo, Tianyun Qiao, Shuwen Li, Ou Li, Ning Chang, Xinxin Zhang, Minzhe Zhang, Dan Qiu, Hangtian Xi, Jinggeng Li, Xiangxiang Chen, Mingxiang Ye, Jian Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionObservational investigations have examined the impact of glucosamine use on the risk of cancer and non-neoplastic diseases. However, the findings from these studies face limitations arising from confounding variables, reverse causation, a
Externí odkaz:
https://doaj.org/article/1bfadc0ab16a43f897c8c4bcd9d50f7a
Autor:
Yanlu Xiong, Yongfu Ma, Kun Liu, Jie Lei, Jinbo Zhao, Jianfei Zhu, Wenchen Wang, Miaomiao Wen, Xuejiao Wang, Ying Sun, Yabo Zhao, Yong Han, Tao Jiang, Yang Liu
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Objective We aim to molecularly stratify stage IA lung adenocarcinoma (LUAD) for precision medicine. Methods Twelve multi-institution datasets (837 cases of IA) were used to classify the high- and low-risk types (based on survival status wit
Externí odkaz:
https://doaj.org/article/3f684fbfe7074ae0a11e4ec5ef2fbb6e
Autor:
Jianfei Zhu, Wenchen Wang, Yanlu Xiong, Shuonan Xu, Jiankuan Chen, Miaomiao Wen, Yabo Zhao, Jie Lei, Tao Jiang
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5545-5557 (2023)
Abstract Objective Mutations in driver genes contribute to the development and progression of lung adenocarcinoma (LUAD). However, in the dynamic evolutionary process from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and ev
Externí odkaz:
https://doaj.org/article/e22718cb2308494f92b063f679a2f4c6
Autor:
Yinxi Zhou, Jinghua Xia, Shuonan Xu, Tao She, Yanning Zhang, Ying Sun, Miaomiao Wen, Tao Jiang, Yanlu Xiong, Jie Lei
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The development and growth of tumors remains an important and ongoing threat to human life around the world. While advanced therapeutic strategies such as immune checkpoint therapy and CAR-T have achieved astonishing progress in the treatment of both
Externí odkaz:
https://doaj.org/article/03ecc517b1df49b992816a86b3d2247e
Autor:
Yanning Zhang, Xuejiao Wang, Yaoqing Yang, Jing Yan, Yanlu Xiong, Wenchen Wang, Jie Lei, Tao Jiang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Lung diseases have become a significant challenge to public healthcare worldwide, which stresses the necessity of developing effective biological models for pathophysiological and pharmacological studies of the human respiratory system. In recent yea
Externí odkaz:
https://doaj.org/article/61de653aebce4f1ba7d3fc80c9a0bd15
Autor:
Shouzheng Ma, Jun Zhu, Mengmeng Wang, Jianfei Zhu, Wenchen Wang, Yanlu Xiong, Runmin Jiang, Lei Liu, Tao Jiang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: The non-negligible role of epigenetic modifications in cancer development and tumor microenvironment (TME) has been demonstrated in recent studies. Nonetheless, the potential regulatory role of N7-methylguanosine (m7G) modification in sha
Externí odkaz:
https://doaj.org/article/0916dd0a31554ba180aab0b7ad9f8c28
Autor:
Yanlu Xiong, Yangbo Feng, Jinbo Zhao, Jie Lei, Tianyun Qiao, Yongsheng Zhou, Qiang Lu, Tao Jiang, Lintao Jia, Yong Han
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-13 (2021)
Abstract Transcription factor AP-2α (TFAP2A) was previously regarded as a critical regulator during embryonic development, and its mediation in carcinogenesis has received intensive attention recently. However, its role in lung adenocarcinoma (LUAD)
Externí odkaz:
https://doaj.org/article/342891e44ddc43378e05b51613a04283
Autor:
Jianyong Sun, Yanlu Xiong, Kuo Jiang, Bo Xin, Tongtong Jiang, Renji Wei, Yuankang Zou, Hong Tan, Tao Jiang, Angang Yang, Lintao Jia, Lei Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) are involved in the hypoxia-related cancer process and play pivotal roles in enabling malignant cells to survive under hypoxic stress. However, the molecul
Externí odkaz:
https://doaj.org/article/858e25555f3c45b8a2ed595ce01719d8
Autor:
Yanlu Xiong, Jie Lei, Jinbo Zhao, Qiang Lu, Yangbo Feng, Tianyun Qiao, Shaowei Xin, Yong Han, Tao Jiang
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Lung adenocarcinoma (LUAD) remains a crucial factor endangering human health. Gene-based clinical predictions could be of great help for cancer intervention strategies. Here, we tried to build a gene-based survival score (SS) for
Externí odkaz:
https://doaj.org/article/ba2cfa11f65c40e2a6e3bb373dba4e8c