Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yanli, Mi"'
Autor:
Yanli, Mi, George, Wood
Publikováno v:
PDA journal of pharmaceutical science and technology. 58(4)
The purpose of this paper is to explore the application and mechanisms of polyethylene glycol 8000 (PEG 8000) on stabilizing lactate dehydrogenase (LDH) during lyophilization. In earlier freeze-thawing experiments, different molecular weights and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4893b8c3f59563a77a42adaacdc4e5f7
https://pubmed.ncbi.nlm.nih.gov/15368989
https://pubmed.ncbi.nlm.nih.gov/15368989
The purpose of this study was to explore the cryoprotection mechanisms of high molecular weight polyethylene glycols (PEGs) (eg, PEG 4000 and PEG 8000) on lactate dehydrogenase (LDH). Ultraviolet activity assays, circular dichroism (CD) spectroscopy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64f5090f21346eb6a1f7912cc2a9bf5
https://europepmc.org/articles/PMC2751247/
https://europepmc.org/articles/PMC2751247/
Publikováno v:
PDA journal of pharmaceutical science and technology. 56(3)
Lactate dehydrogenase (LDH) is a tetrameric enzyme that has been used as a model for labile protein drugs. Polyethylene glycols (PEGs) have been proposed as excipients to stabilize labile proteins in solution and during the freezing portion of the ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d693d03b539f95eaf5902ae8944a15bf
https://pubmed.ncbi.nlm.nih.gov/12109331
https://pubmed.ncbi.nlm.nih.gov/12109331