Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Yanlei Yu"'
Autor:
Keren Xu, Leyi Ying, Titi Ying, Qihao Wu, Lin Du, Yanlei Yu, Youmin Ying, Bin Wei, Hong Wang, Zhikun Yang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
EcGUS has drawn considerable attention for its role as a target in alleviating serious GIAEs. In this study, a series of 72 (thio)urea derivatives were designed, synthesised, and biologically assayed. The bioassay results revealed that E-9 (IC50 = 2.
Externí odkaz:
https://doaj.org/article/deeac22ae7ec4be2ae1419250671037f
Autor:
Xuejun Lu, Manlai Zhang, Yixian Qiu, Xiuxiu Liu, Cancan Wang, Jianwei Chen, Huawei Zhang, Bin Wei, Yanlei Yu, Youmin Ying, Kui Hong, Hong Wang
Publikováno v:
Molecules, Vol 28, Iss 9, p 3822 (2023)
α-Glucosidase (AGS) inhibitors have been regarded as an ideal target for the management of type 2 diabetes mellitus (T2DM) since they can maintain an acceptable blood glucose level by delaying the digestion of carbohydrates and diminishing the absor
Externí odkaz:
https://doaj.org/article/066032740bc84a73a1dd40272007a860
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Creating an enhanced-security-level label that carries entirely distinct information in different optical states has proven challenging. Here, the authors design geminate labels by programming fluorescent cholesteric liquid crystal microdroplets to e
Externí odkaz:
https://doaj.org/article/561b07c4ed5e44d79a70818080cc927a
Autor:
Jingyi Wu, Ye Tian, Lu Han, Chao Liu, Tianyu Sun, Ling Li, Yanlei Yu, Bikash Lamichhane, Rena N. D’Souza, Sarah E. Millar, Robb Krumlauf, David M. Ornitz, Jian Q. Feng, Ophir Klein, Hu Zhao, Fuming Zhang, Robert J. Linhardt, Xiaofang Wang
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background The formation of supernumerary teeth is an excellent model for studying the molecular mechanisms that control stem/progenitor cell homeostasis needed to generate a renewable source of replacement cells and tissues. Although multip
Externí odkaz:
https://doaj.org/article/d075ac87bfca4c4f89c5fdce533e9fd6
Autor:
Gretchen T Clark, Yanlei Yu, Cooper A Urban, Guo Fu, Chunyu Wang, Fuming Zhang, Robert J Linhardt, Jennifer M Hurley
Publikováno v:
PLoS Genetics, Vol 18, Iss 2, p e1009994 (2022)
Alzheimer's Disease (AD) is a neuroinflammatory disease characterized partly by the inability to clear, and subsequent build-up, of amyloid-beta (Aβ). AD has a bi-directional relationship with circadian disruption (CD) with sleep disturbances starti
Externí odkaz:
https://doaj.org/article/f1812de39f4e451d97c846f31d199435
Autor:
Ying Song, Dongze Lu, Honggang Wang, Zhenyi Zhou, Xian Luo, Manjing Ma, Songze Ke, Hong Wang, Yanlei Yu, Bin Wei
Publikováno v:
Foods, Vol 12, Iss 3, p 665 (2023)
Saccharina japonica polysaccharides exhibit great potential to be developed as anti-obesity and prebiotic health products, but the underlying mechanism has not been adequately addressed. In this study, we investigated the potential mechanism of a S.
Externí odkaz:
https://doaj.org/article/01936423e1814f6484598cb2a367dd9f
Publikováno v:
Advanced Intelligent Systems, Vol 3, Iss 10, Pp n/a-n/a (2021)
Azobenzene‐containing liquid crystal polymers (azo‐LCPs) with reactive groups attract much attention due to the combined properties of liquid crystallinity, photoresponsivity and reactivity, which make them promising in designing intelligent phot
Externí odkaz:
https://doaj.org/article/fd434f38ee464218a6ae8bb91ac12333
Autor:
Asher Williams, Kamil S. Gedeon, Deepika Vaidyanathan, Yanlei Yu, Cynthia H. Collins, Jonathan S. Dordick, Robert J. Linhardt, Mattheos A. G. Koffas
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-13 (2019)
Abstract Background Heparosan is the unsulfated precursor of heparin and heparan sulfate and its synthesis is typically the first step in the production of bioengineered heparin. In addition to its utility as the starting material for this important
Externí odkaz:
https://doaj.org/article/153766fdafe74e05b7ab3447aaa4e4a6
Autor:
Yi Wang, Xiangli Zhang, Wenya Zhuang, Yanlei Yu, Xuanrong Sun, Hong Wang, Fengzhi Li, Qingyong Li
Publikováno v:
Molecules, Vol 27, Iss 12, p 3669 (2022)
Irinotecan and Topotecan are two Camptothecin derivatives (CPTs) whose resistance is associated with the high expression of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp). To reverse this resistance, two novel CPTs, FL77-28 (7-(3-F
Externí odkaz:
https://doaj.org/article/04a149ba86554f40be36b934c3fbbc2f
Publikováno v:
Giant, Vol 2, Iss , Pp 100019- (2020)
Manipulating small water droplets on an intelligent surface with tunable superhydrophobic adhesion has attracted considerable interests because of potential applications ranging from no-loss transfer to surface chemistry but remains challenging. Here
Externí odkaz:
https://doaj.org/article/87bf0f3ecc6440ce806fd7d25bb0d355