Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

Autor: Yankier Pijeira Perez, Eifiona Wood, Dyfrig A Hughes

Publikováno v: Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-8 (2023)

Abstract Background The Orphan Regulation ((EC) No 141/2000) has successfully redirected private and public investment towards previously neglected areas through incentives, regulatory obligations and rewards. However, the growth in the number of lic

Externí odkaz: https://doaj.org/article/be581134551441ebb3b366087c16bb91

Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs.

Autor: Marson, Anthony G., Burnside, Girvan, Appleton, Richard, Smith, Dave, Leach, John Paul, Sills, Graeme, Tudur-Smith, Catrin, Plumpton, Catrin O., Hughes, Dyfrig A., Williamson, Paula R., Baker, Gus, Balabanova, Silviya, Taylor, Claire, Brown, Richard, Hindley, Dan, Howell, Stephen, Maguire, Melissa, Mohanraj, Rajiv, Smith, Philip E. M.

Publikováno v: Health Technology Assessment; 12/17/2021, Vol. 25 Issue 75, pvii-134, 147p

Evidence Following Conditional NICE Technology Appraisal Recommendations: A Critical Analysis of Methods, Quality and Risk of Bias.

Autor: Pijeira Perez Y; Centre for Health Economics and Medicines Evaluation, Bangor University, Ardudwy, Normal Site, Holyhead Road, Bangor, Gwynedd, Wales, LL57 2PZ, UK., Hughes DA; Centre for Health Economics and Medicines Evaluation, Bangor University, Ardudwy, Normal Site, Holyhead Road, Bangor, Gwynedd, Wales, LL57 2PZ, UK. d.a.hughes@bangor.ac.uk.

Publikováno v: PharmacoEconomics [Pharmacoeconomics] 2024 Dec; Vol. 42 (12), pp. 1373-1394. Date of Electronic Publication: 2024 Sep 09.