Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yanjian Li"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Cryptococcus neoformans is a life-threatening fungal pathogen that is a causative agent for pulmonary infection and meningoencephalitis in both immunocompetent and immunodeficient individuals. Recent studies have elucidated the important fun
Externí odkaz:
https://doaj.org/article/04e23c0845d14e4db10a4b152be2293f
Autor:
Sally H. Mohamed, Man Shun Fu, Sofia Hain, Alanoud Alselami, Eliane Vanhoffelen, Yanjian Li, Ebrima Bojang, Robert Lukande, Elizabeth R. Ballou, Robin C. May, Chen Ding, Greetje Vande Velde, Rebecca A. Drummond
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Microglia provide protection against a range of brain infections including bacteria, viruses and parasites, but how these glial cells respond to fungal brain infections is poorly understood. We investigated the role of microglia in the conte
Externí odkaz:
https://doaj.org/article/b28b9206e7b54ba180a25dd72db4ddce
Autor:
Yang Meng, Yue Ni, Zhuoran Li, Tianhang Jiang, Tianshu Sun, Yanjian Li, Xindi Gao, Hailong Li, Chenhao Suo, Chao Li, Sheng Yang, Tian Lan, Guojian Liao, Tongbao Liu, Ping Wang, Chen Ding
Publikováno v:
eLife, Vol 13 (2024)
Cryptococcus neoformans poses a threat to human health, but anticryptococcal therapy is hampered by the emergence of drug resistance, whose underlying mechanisms remain poorly understood. Herein, we discovered that Isw1, an imitation switch chromatin
Externí odkaz:
https://doaj.org/article/97632ab4fa994da98f181bd6c8377933
Autor:
Hailong Li, Xiaoxu Han, Wei Du, Yang Meng, Yanjian Li, Tianshu Sun, Qiaojing Liang, Chao Li, Chenhao Suo, Xindi Gao, Yu Qiu, Wen Tian, Minghui An, Hui Zhang, Yajing Fu, Xiaolin Li, Tian Lan, Sheng Yang, Zining Zhang, Wenqing Geng, Chen Ding, Hong Shang
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1572-1585 (2022)
Cryptococcal meningoencephalitis (CM) is emerging as an infection in HIV/AIDS patients shifted from primarily ARTnaive to ART-experienced individuals, as well as patients with COVID-19 and immunocompetent hosts. This fungal infection is mainly caus
Externí odkaz:
https://doaj.org/article/d01c0a502d44448f880ce60a76473ffb
Autor:
Xindi Gao, Yi Fu, Shengyi Sun, Tingyi Gu, Yanjian Li, Tianshu Sun, Hailong Li, Wei Du, Chenhao Suo, Chao Li, Yiru Gao, Yang Meng, Yue Ni, Sheng Yang, Tian Lan, Sixiang Sai, Jiayi Li, Kun Yu, Ping Wang, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Mitochondrial quality control prevents accumulation of intramitochondrial reactive oxygen species (mtROS), thus protecting cells against DNA damage. Here, Gao et al. show that an atypical heat shock factor responds to intramitochondrial stresses and
Externí odkaz:
https://doaj.org/article/9e1bb7e29f054a049103c7d56d8bf999
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Candida pelliculosa is an ecological fungal species that can cause infections in immunocompromised individuals. Numerous studies globally have shown that C. pelliculosa infects neonates. An outbreak recently occurred in our neonat
Externí odkaz:
https://doaj.org/article/c05b28260d424d1083ce9c6d63bf4b70
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Prevalence of fungal diseases has increased globally in recent years, which often associated with increased immunocompromised patients, aging populations, and the novel Coronavirus pandemic. Furthermore, due to the limitation of available antifungal
Externí odkaz:
https://doaj.org/article/17314e7c4f194f2e9fd0370242421bd9
Autor:
Tianshu Sun, Yanjian Li, Yingxing Li, Hailong Li, Yiyi Gong, Jianqiang Wu, Yating Ning, Chen Ding, Yingchun Xu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Cryptococcus neoformans is an invasive human fungal pathogen that causes more than 181,000 deaths each year. Studies have demonstrated that pulmonary C. neoformans infection induces innate immune responses involving copper, and copper detoxification
Externí odkaz:
https://doaj.org/article/7f296224d8d845d3aacf1da7278db95f
Integrative Proteome and Acetylome Analyses of Murine Responses to Cryptococcus neoformans Infection
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cryptococcus neoformans is a causative agent for pulmonary infection and meningoencephalitis. Understanding the host’s response to C. neoformans infection is critical for developing effective treatment. Even though some have elucidated the host res
Externí odkaz:
https://doaj.org/article/5ba61ea4ac684f108c5df88475e34c34
Autor:
Zhengyu Liang, Guipeng Li, Zejun Wang, Mohamed Nadhir Djekidel, Yanjian Li, Min-Ping Qian, Michael Q. Zhang, Yang Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Chromatin interactions and genome architecture are key regulators of gene expression. Here the authors present Bridge-Linker-Hi-C to map active chromatin loops and enhancer-promoter interactions.
Externí odkaz:
https://doaj.org/article/770153faabde43249cd319d518f6b96c