Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yanjia Fang"'
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-4 (2023)
Abstract WDR5 is a highly conserved protein that performs multiple scaffolding functions in the context of chromatin. However, efforts to understand the function of WDR5 in normal tissues physiologically are quite limited so far. In our study, we exp
Externí odkaz:
https://doaj.org/article/1e2bd9a8838c4abd974685c5604f183a
Publikováno v:
European Journal of Medicinal Chemistry. 132:157-172
The inhibition of CYP17 to block androgen biosynthesis is a well validated strategy for the treatment of prostate cancer. Herein we reported the design, synthesis and structure–activity relationship (SAR) study for a series of novel 1,2,3,4- tetrah
Autor:
Hengyi Cao, Chunli Lou, Yanjia Fang, Lin Sun, Jingwu Kang, Wanguo Wei, Taijie Jin, Jianhua Yi, Ge Chen, Ying Li, Jidong Zhu, Chunyi Niu
Publikováno v:
Journal of medicinal chemistry. 62(6)
Triapine, an iron chelator that inhibits ribonucleotide reductase, has been evaluated in clinical trials for cancer treatment. Triapine in combination with other chemotherapeutic agents shows promising efficacy in certain hematologic malignancies; ho
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Protooncogene c-MYC, a master transcription factor, is a major driver of human tumorigenesis. Development of pharmacological agents for inhibiting c-MYC as an anticancer therapy has been a longstanding but elusive goal in the cancer field. E3 ubiquit
Autor:
Jingjing Xie, Xiaojia Si, Shoulai Gu, Mingliang Wang, Jian Shen, Haoyan Li, Dan Li, Yanjia Fang, Cong Liu, Jidong Zhu
Publikováno v:
Journal of medicinal chemistry. 60(24)
SHP2, a cytoplasmic protein-tyrosine phosphatase encoded by the PTPN11 gene, is involved in multiple cell signaling processes including Ras/MAPK and Hippo/YAP pathways. SHP2 has been shown to contribute to the progression of a number of cancer types
Autor:
Jianfeng Liu, Chris Lu, Yan Zhang, Peter Atadja, Mengxi Zhao, Wei Tan, Chao Zhang, Yanjia Fang, Ting Mao, Zhaofu Wang, Yan Wang, Zongyao Wang, Xiao Luo, Kehao Zhao, He Wang, Zhui Chen, Irene Zang, Haiyan Ying, En Li, Ying Lin, Yuan Lu, Justin Gu, Wei Xiao, Jianwu Fang
Publikováno v:
Oncotarget
// Jianwu Fang 1, 2 , Haiyan Ying 2 , Ting Mao 2 , Yanjia Fang 2 , Yuan Lu 2 , He Wang 2 , Irene Zang 2 , Zhaofu Wang 2 , Ying Lin 2 , Mengxi Zhao 2 , Xiao Luo 2 , Zongyao Wang 2 , Yan Zhang 2 , Chao Zhang 2 , Wei Xiao 2 , Yan Wang 2 , Wei Tan 2 , Zh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/2/2018, Vol. 115 Issue 40, pE9317-E9324, 8p
Autor:
Shoulai Gu, Yanjia Fang, Cong Liu, Jidong Zhu, Jingjing Xie, Haoyan Li, Jian Shen, Xiaojia Si, Mingliang Wang, Dan Li
Publikováno v:
Journal of Medicinal Chemistry; 12/28/2017, Vol. 60 Issue 24, p10205-10219, 15p
Autor:
Yan-Ai Mei, Yanjia Fang
Publikováno v:
Neuroscience Research. 68:e447