Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yanji Xu"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0289518 (2024)
Drug repurposing is a strategy for identifying new uses of approved or investigational drugs that are outside the scope of the original medical indication. Even though many repurposed drugs have been found serendipitously in the past, the increasing
Externí odkaz:
https://doaj.org/article/c5a74157b6c5458da29968b1c9bcf6b0
Autor:
William Z. Kariampuzha, Gioconda Alyea, Sue Qu, Jaleal Sanjak, Ewy Mathé, Eric Sid, Haley Chatelaine, Arjun Yadaw, Yanji Xu, Qian Zhu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background The United Nations recently made a call to address the challenges of an estimated 300 million persons worldwide living with a rare disease through the collection, analysis, and dissemination of disaggregated data. Epidemiologic In
Externí odkaz:
https://doaj.org/article/97c68f5ddac148e2af07b15e158462a3
Autor:
Qian Zhu, Ðắc-Trung Nguyễn, Timothy Sheils, Gioconda Alyea, Eric Sid, Yanji Xu, James Dickens, Ewy A. Mathé, Anne Pariser
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background Limited knowledge and unclear underlying biology of many rare diseases pose significant challenges to patients, clinicians, and scientists. To address these challenges, there is an urgent need to inspire and encourage scientists t
Externí odkaz:
https://doaj.org/article/6436e90bae0b4f9dbe8bc63d5bd9cd97
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
Externí odkaz:
https://doaj.org/article/f3696c4a19554bd89f913f89012ce443
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
Social media has become an important resource for discussing, sharing, and seeking information pertinent to rare diseases by patients and their families, given the low prevalence in the extraordinarily sparse populations. In our previous study, we id
Externí odkaz:
https://doaj.org/article/5186662befaf49bcae31550370db8330
Autor:
Qian Zhu, Chunxu Qu, Ruizheng Liu, Gunjan Vatas, Andrew Clough, Ðắc-Trung Nguyễn, Eric Sid, Ewy Mathé, Yanji Xu
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
Rare diseases (RDs) are naturally associated with a low prevalence rate, which raises a big challenge due to there being less data available for supporting preclinical and clinical studies. There has been a vast improvement in our understanding of RD
Externí odkaz:
https://doaj.org/article/8284dbf2556648699100eb6a3653f156
Autor:
William Z. Kariampuzha, Gioconda Alyea, Sue Qu, Jaleal Sanjak, Ewy Mathé, Eric Sid, Haley Chatelaine, Arjun Yadaw, Yanji Xu, Qian Zhu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d37d48a7b5a74170b5701070fb5040d3
Publikováno v:
Molecules, Vol 27, Iss 20, p 7130 (2022)
Tuberculosis remains an important cause of morbidity and mortality throughout the world. Notably, an important number of multi drug resistant cases is an increasing concern. This problem points to an urgent need for novel compounds with antimycobacte
Externí odkaz:
https://doaj.org/article/3f48157365ce47c49a261e76e4d08341
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106788 (2014)
The lymphocyte-specific transcription factor Interferon (IFN) Regulatory Factor 4 (IRF4) is implicated in certain types of lymphoid and myeloid malignancies. However, the molecular mechanisms underlying its interactions with these malignancies are la
Externí odkaz:
https://doaj.org/article/90e16643f73d498396659a80f64caa3a
Autor:
Marco Ricci, Yanji Xu, Harriet L Hammond, David A Willoughby, Lubov Nathanson, Maria M Rodriguez, Matteo Vatta, Steven E Lipshultz, Joy Lincoln
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29784 (2012)
Hypoplastic Left Heart Syndrome (HLHS) is a congenital defect characterized by underdevelopment of the left ventricle and pathological compensation of the right ventricle. If untreated, HLHS is invariably lethal due to the extensive increase in right
Externí odkaz:
https://doaj.org/article/2fc4220f1b0f4b2289f0a544df2e37bc