PD1 ligand functionality a biomarker of response to anti PD1 treatment in patients with HNSCC

Autor: Bar Kaufman, Tarek Taha, Orli Abramov, Yaniv Zohar, Kamel Mhameed, Ofir Cohen, Angel Porgador, Moshe Elkabets, Salem Billan

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)

Abstract Therapies targeting the PD-1/PD-L1 pathway have transformed head and neck squamous cell carcinoma (HNSCC) treatment. However, predicting the response to anti-PD-1 therapy remains a clinical challenge. This study evaluated the functional bind

Externí odkaz: https://doaj.org/article/d5f6768c30924b929faf4d6be7a889a4

Liver fibrosis among infants with t(1;22)(p13;q13) acute megakaryoblastic leukemia: a case report and literature review

Autor: Nira Arad-Cohen, Ori Attias, Yaniv Zohar, Yoav H. Messinger

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

This case report describes a 2-month-old girl with acute megakaryoblastic leukemia (AMKL) harboring the t(1;22)(p13;q13) translocation, resulting in the RBM15::MRTFA fusion gene. She presented with massive hepatosplenomegaly and liver fibrosis and ac

Externí odkaz: https://doaj.org/article/6717e1a833324ca987a961e9098df4d3

Novel TSPO Ligand 2-Cl-MGV-1 Can Counteract Lipopolysaccharide Induced Inflammatory Response in Murine RAW264.7 Macrophage Cell Line and Lung Models

Autor: Fadi Obeid, Meygal Kahana, Baraah Dahle, Sheelu Monga, Yaniv Zohar, Abraham Weizman, Moshe Gavish

Publikováno v: Cells, Vol 13, Iss 20, p 1702 (2024)

We assessed the anti-inflammatory activity of the TSPO ligand 2-Cl-MGV-1. Lipopolysaccharide (LPS) was used to induce inflammatory response in a murine RAW264.7 macrophage model (LPS: 100 ng/mL) and a mouse model (C57BL/6) of lung inflammation (LPS:

Externí odkaz: https://doaj.org/article/363423260ce842a28b37014a129ba3a7

Management of Chronic Anal Fissure with a Novel Topical Hemp-Herbal-Based Ointment: A Pilot Study

Autor: Edward Ram, Yaniv Zager, Raanan Meyer, Dan Carter, Samia Joubran, Nir Horesh

Publikováno v: Medical Cannabis and Cannabinoids, Vol 6, Iss 1, Pp 15-20 (2023)

Introduction: Anal fissure (AF) is a common anorectal disease. Although several pharmacological treatments are available, many patients still require surgical interventions. In this study, we aimed to evaluate the efficacy of an ointment based on a m

Externí odkaz: https://doaj.org/article/a8127072f2774075bf3d99c80ef68f6a

Синтез и противомикробная активность продуктов анионарилирования, содержащих сульфаниламидный фрагмент

Autor: Yaniv, Z. I., Symchak, R. V., Pokryshko, O. V., Tulaydan, H. M., Baranovskyy, V. S., Klymnyuk, S. I., Grishchuk, B. D.

Publikováno v: Журнал органічної та фармацевтичної хімії; Том 14, № 2(54) (2016): Журнал органічної та фармацевтичної хімії; 60-64
Žurnal organìčnoï ta farmacevtičnoï hìmìï; Том 14, № 2(54) (2016): Žurnal organìčnoï ta farmacevtičnoï hìmìï; 60-64
Журнал органической и фармацевтической химии; Том 14, № 2(54) (2016): Журнал органической и фармацевтической химии; 60-64

Реакцією аніонарилювання синтезовані продукти, що містять сульфаніламідний фрагмент. Взаємодією тетрафлуороборату 4-сульфамідофенілд

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=scientific_p::47a7dc6bf4f9cbc59013f6f3e452a220
http://ophcj.nuph.edu.ua/article/view/ophcj.16.883