Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yaniv Tivon"'
Autor:
Elisa Ruffo, Adam A. Butchy, Yaniv Tivon, Victor So, Michael Kvorjak, Avani Parikh, Eric L. Adams, Natasa Miskov-Zivanov, Olivera J. Finn, Alexander Deiters, Jason Lohmueller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Chimeric antigen receptors (CARs) and synthetic Notch (synNotch) receptors are engineered cell-surface receptors that sense a target antigen and respond by activating T cell receptor signaling or a customized gene program, respectively. Here
Externí odkaz:
https://doaj.org/article/0970abb68a6945a4967176ad1a042aa8
Autor:
Michael Kvorjak, Elisa Ruffo, Yaniv Tivon, Victor So, Avani B. Parikh, Alexander Deiters, Jason Lohmueller
Publikováno v:
bioRxiv
As living drugs, engineered T cell therapies are revolutionizing disease treatment with their unique functional capabilities. However, they suffer from limitations of potentially unpredictable behavior, toxicities, and non-traditional pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ef38dc415718d10f45b13ea636657c
https://europepmc.org/articles/PMC10245878/
https://europepmc.org/articles/PMC10245878/
Publikováno v:
Angew Chem Int Ed Engl
Methods in Enzymology ISBN: 9780443185922
Methods in Enzymology ISBN: 9780443185922
We developed a new approach to selectively modify native proteins in their biological environment using electrophilic covalent aptamers. These aptamers are generated through introduction of a proximity-driven electrophile at specific nucleotide sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4011396fd76cb8f2254d1627eb4412
https://europepmc.org/articles/PMC8260448/
https://europepmc.org/articles/PMC8260448/
Autor:
Natasa Miskov-Zivanov, Olivera J. Finn, Alexander Deiters, Jason Lohmueller, Michael Kvorjak, Yaniv Tivon, Adam A. Butchy
Chimeric antigen receptors (CARs) and synthetic Notch (synNotch) receptors are engineered cell-surface receptors that sense a target antigen and respond by activating T cell receptor signaling or a customized gene program, respectively. To expand the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545d5a08f92f70f2667e49b6bbe219e5
https://doi.org/10.1101/2020.01.17.909895
https://doi.org/10.1101/2020.01.17.909895
Autor:
Alexander Deiters, Yuta Naro, Meryl Thomas, Laura Gardner, Colleen M. Connelly, Yaniv Tivon, Nicholas Ankenbruck
Publikováno v:
Journal of medicinal chemistry. 61(14)
Chemical probes of microRNA (miRNA) function are potential tools for understanding miRNA biology that also provide new approaches for discovering therapeutics for miRNA-associated diseases. MicroRNA-21 (miR-21) is an oncogenic miRNA that is overexpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8fcaeaff4153e90661eae3793ed18b
https://pubmed.ncbi.nlm.nih.gov/29993250
https://pubmed.ncbi.nlm.nih.gov/29993250
Autor:
Jason Jakob Lomueller, Adam Butchy, Yaniv Tivon, Michael Kvorjak, Natasa Miskov-Zivanov, Alexander Deiters, Olivera J Finn
Publikováno v:
The Journal of Immunology. 202:71.18-71.18
Chimeric antigen receptors (CARs) are artificial T cell receptors that re-target patients’ T cells to specifically bind and kill tumor cells. Adoptive cell therapy with CAR T cells targeting CD19 has revolutionized treatment of refractory B cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab1f22791a4707f6ced2fbe1bccdcd5
https://doi.org/10.4049/jimmunol.202.supp.71.18
https://doi.org/10.4049/jimmunol.202.supp.71.18