Výsledky vyhledávání - "Yanina Ditamo"

Akademický článek

Irreversible incorporation of L-dopa into the C-terminus of α-tubulin inhibits binding of molecular motor KIF5B to microtubules and alters mitochondrial traffic along the axon

Autor: Agustina Zorgniotti, Yanina Ditamo, Carlos A. Arce, C. Gaston Bisig

Publikováno v: Neurobiology of Disease, Vol 147, Iss , Pp 105164- (2021)

L-dopa is the most effective drug used to date for management of Parkinson's disease symptoms. Unfortunately, long-term administration of L-dopa often results in development of motor disorders, including dyskinesias. Despite extensive research on L-d

Externí odkaz: https://doaj.org/article/70a7be6034cf48b3a0dbbf4bbdd1434e

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Telomere-led meiotic chromosome movements: recent update in structure and function

Autor: Yanina Ditamo, M. N. Conrad, Michael E. Dresser, L. Previato de Almeida, Chih-Ying Lee, Roberto J. Pezza, Carlos Gaston Bisig

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nucleus
article-version (VoR) Version of Record
Nucleus, Vol 11, Iss 1, Pp 111-116 (2020)

In S. cerevisiae prophase meiotic chromosomes move by forces generated in the cytoplasm and transduced to the telomere via a protein complex located in the nuclear membrane. We know that chromosome movements require actin cytoskeleton [13,31] and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233a597c8e1f0e46f0eae09aee9ff8fe
https://doi.org/10.1080/19491034.2020.1769456

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Extranuclear Structural Components that Mediate Dynamic Chromosome Movements in Yeast Meiosis

Autor: C. Gastón Bisig, Luciana Previato de Almeida, Chih-Ying Lee, Michael E. Dresser, Michael M. Conrad, Roberto J. Pezza, Yanina Ditamo

Publikováno v: Curr Biol
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Telomere-led rapid chromosome movements or rapid prophase movements direct fundamental meiotic processes required for successful haploidization of the genome. Critical components of the machinery that generates rapid prophase movements are unknown, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878628a8482812d537df2be87209a4df
https://europepmc.org/articles/PMC7181386/

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Post-translational incorporation of 3,4-dihydroxyphenylalanine into the C terminus of α-tubulin in living cells

Autor: Yanina Ditamo, Yanela Melani Dentesano, Cristian Hansen, Carlos Gaston Bisig, Carlos A. Arce

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The C-terminal tyrosine (Tyr) of the α-tubulin chain is subjected to post-translational removal and readdition in a process termed the “detyrosination/tyrosination cycle”. We showed in previous studies using soluble rat brain extracts that l-3,4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f228ff44c184e58ae96e623be3b22e
https://pubmed.ncbi.nlm.nih.gov/29341414

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Extrinsic functions of lectin domains in O-N-acetylgalactosamine glycan biosynthesis

Autor: Fernando J. Irazoqui, Gustavo A. Nores, Henrik Clausen, Yanina Ditamo, Romina B. Cejas, Virginia Lorenz, Eric P. Bennett, Maria E. Carrizo

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Glycan biosynthesis occurs mainly in Golgi. Molecular organization and functional regulation of this process are not well understood. We evaluated the extrinsic effect of lectin domains (β-trefoil fold) of polypeptide GalNAc-transferases (ppGalNAc-T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32319b894bee66dc6473a349633e8030
http://www.jbc.org/content/291/49/25339

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In vivo immunomodulatory effect of the lectin from edible mushroom Agaricus bisporus

Autor: Gustavo A. Nores, Victor G. Sendra, Gabriel Fabian Roth, Yanina Ditamo, Fernando J. Irazoqui, Lucia L. Rupil

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Lectins are glycan-binding proteins that are resistant to digestion in the gastrointestinal tract and enter intact to blood circulation. The aim of this study was to evaluate the influence of edible mushroom Agaricus bisporus lectin (ABL) on innate a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f988a6f53787d5a2b42298bda6c5b231
http://pubs.rsc.org/en/Content/ArticleLanding/2016/FO/C5FO00360A#!divAbstract

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Neonatal mucosal immunization with a non-living, non-genetically modified Lactococcus lactis vaccine carrier induces systemic and local Th1-type immunity and protects against lethal bacterial infection

Autor: Liliana Rodriguez, Wendy L. Picking, M L van Roosmalen, Marcela F. Pasetti, Yanina Ditamo, Karina Ramirez, Kees Leenhouts

Publikováno v: Mucosal immunology

Safe and effective immunization of newborns and infants can significantly reduce childhood mortality, yet conventional vaccines have been largely unsuccessful in stimulating the neonatal immune system. We explored the capacity of a novel mucosal anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58c8b131f4d31853a764b8d357b08e1
https://doi.org/10.1038/mi.2009.131

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Glycan bioengineering in immunogen design for tumor T antigen immunotargeting

Autor: Gustavo A. Nores, Henrik Clausen, Natacha Zlocowski, Yanina Ditamo, Mads Agervig Tarp, German A. Roth, Eric P. Bennett, Silvina Copioli, Fernando J. Irazoqui, Victor G. Sendra

Publikováno v: Molecular Immunology. 46:3445-3453

Bioengineering of Galbeta3GalNAcalpha, known as Thomsen-Friedenreich disaccharide (TFD), is studied to promote glycan immunogenicity and immunotargeting to tumor T antigen (Galbeta3GalNAcalpha-O-Ser/Thr). Theoretical studies on disaccharide conformat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f528e83f11faeddf838e165f102d5678
https://doi.org/10.1016/j.molimm.2009.08.007

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Nitric oxide mediates the suppressive effect of testosterone on cell proliferative response to myelin basic protein

Autor: Laura Fozzatti, Daniela R. Macció, German A. Roth, Ana María Masini-Repiso, Yanina Ditamo

Publikováno v: Journal of Neuroimmunology. 199:63-66

This study assessed whether the in vitro effect of testosterone on the proliferative response of mononuclear cells to myelin basic protein (MBP) could be mediated by nitric oxide (NO). Testosterone but not cholesterol supplementation specifically sup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1703885f2666410e41dd6f70185f094
https://doi.org/10.1016/j.jneuroim.2008.05.005

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