Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yanice V Mendez-Fernandez"'
Autor:
Kevin D Pavelko, Megan A Girtman, Yoshihiro Mitsunaga, Yanice V Mendez-Fernandez, Michael P Bell, Michael J Hansen, Kathleen S Allen, Moses Rodriguez, Larry R Pease
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20217 (2011)
The induction of sterilizing T-cell responses to tumors is a major goal in the development of T-cell vaccines for treating cancer. Although specific components of anti-viral CD8+ immunity are well characterized, we still lack the ability to mimic vir
Externí odkaz:
https://doaj.org/article/e5ea32cb816042768471f0c82d886e5e
Autor:
Amy S. Major, Thirumala-Devi Kanneganti, Ashley J. Wilhelm, John R. Lukens, Jared L. Moore, Jillian P. Rhoads, Yanice V. Mendez-Fernandez
Publikováno v:
The Journal of Immunology. 198:2105-2114
Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of cells, especially macrophages and dendritic cells. Interestingly, much of the oxLDL in circulation is complexed to Abs, and these resulting immune co
Autor:
John J.P. Kastelein, Sander I. van Leuven, Paul P. Tak, Yanice V. Mendez-Fernandez, Ashley J. Wilhelm, Nekeithia S. Wade, Amy S. Major, Curtis L. Gabriel, Erik S.G. Stroes
Publikováno v:
Annals of the rheumatic diseases, 71(3), 408-414. BMJ Publishing Group
RationaleRecent clinical and preclinical studies have demonstrated that systemic lupus erythematosus (SLE) is associated with an increased risk for cardiovascular disease (CVD). However, unlike in the general population, little is known regarding the
Autor:
Sander I. van Leuven, Erik S.G. Stroes, Paul P. Tak, Yanice V. Mendez-Fernandez, Amy S. Major
Publikováno v:
Annals of the rheumatic diseases, 70(2), 245-248. BMJ Publishing Group
The atherosclerotic process is accelerated in patients with systemic lupus erythematosus (SLE). In addition to a robust lipid-lowering effect, various immunomodulatory functions have been ascribed to statins. By virtue of the latter they may be able
Autor:
Roman Covarrubias, Amy S. Major, Yanice V. Mendez-Fernandez, Nekeithia S. Wade, Joseph L. Witztum, Cody J. Diehl, Sander I. van Leuven, Bonnie G. Stevenson, Nicole A. Braun
Publikováno v:
Atherosclerosis. 214:73-80
Atherosclerosis is widely accepted as an inflammatory disease involving both innate and adaptive immunity. B cells and/or antibodies have previously been shown to play a protective role against atherosclerosis. Aside from their ability to bind to ant
Autor:
Hideo Yagita, Luc Van Kaer, Roman Covarrubias, Nicole A. Braun, Steven A. Porcelli, Paul B. Savage, Amy S. Major, Yanice V. Mendez-Fernandez
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 30:1758-1765
Objective— In this study, we investigated whether dyslipidemia-associated perturbed invariant natural killer T (iNKT) cell function is due to intrinsic changes in iNKT cells or defects in the ability of antigen-presenting cells to activate iNKT cel
Autor:
Saif Lalani, Yanice V. Mendez-Fernandez, Luc Van Kaer, Danyvid Olivares-Villagómez, Vrajesh V. Parekh, Hilde Cheroutre, Tiffaney Vincent
Publikováno v:
Proceedings of the National Academy of Sciences. 105:17931-17936
Intestinal intraepithelial lymphocytes (IEL) bear a partially activated phenotype that permits them to rapidly respond to antigenic insults. However, this phenotype also implies that IEL must be highly controlled to prevent misdirected immune reactio
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9307-9312
Differentiation of T helper (Th) subset 2 effector lymphocytes is thought to foreclose on IFN-γ gene expression. Using an IL-4 locus modified to detect transcriptional induction of this effector cytokine gene in developing Th2 cells, we show here th
Autor:
Larry R. Pease, Yanice V. Mendez-Fernandez, Moses Rodriguez, Matthew S. Block, Virginia P. Van Keulen, Kathleen S. Allen, Michael J. Hansen, Anya L. Taboas
Publikováno v:
The Journal of Immunology. 174:2756-2762
Natural selection drives diversification of MHC class I proteins, but the mechanism by which selection for polymorphism occurs is not known. New variant class I alleles differ from parental alleles both in the nature of the CD8 T cell repertoire form
Publikováno v:
Journal of Virology. 79:3063-3070
Theiler's murine encephalomyelitis virus (TMEV) infection of the brain induces a virus-specific CD8+T-cell response in genetically resistant mice. The peak of the immune response to the virus occurs 7 days after infection, with an immunodominant CD8+