Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yanhan Jia"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Paired box 1 (PAX1) is a transcription factor and essential for the development of pharyngeal pouches-derived tissues, including thymus. PAX1 mutations are identified in Severe Combined Immunodeficiency (SCID) patients with Otofac
Externí odkaz:
https://doaj.org/article/48a94726aadc40899b5c41c68f91c98e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Transcription factors play multifaceted roles in embryonic development and diseases. PAX1, a paired-box transcription factor, has been elucidated to play key roles in multiple tissues during embryonic development by extensive studies. Recently, an em
Externí odkaz:
https://doaj.org/article/6c5c196397a8440a9aad181d41f4698c
Publikováno v:
Cellular signalling. 101
The underlying mechanisms by which cellular metabolism affects cervical cancer cell radiosensitivity remain poorly understood. Here, we found that loss of 3-hydroxy-3-methylglutaryl coenzyme A synthase 1 (HMGCS1), a key enzyme catalyzing the conversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc414d1e9b6260c797c054fc98358f46
https://pubmed.ncbi.nlm.nih.gov/36328117
https://pubmed.ncbi.nlm.nih.gov/36328117
Autor:
Zhenyu Zhu, Meihua Gong, Weipeng Gong, Bishi Wang, Changhao Li, Qingsheng Hou, Hongliang Guo, Jie Chai, Jie Guan, Yanhan Jia
Publikováno v:
Clinical and experimental medicine.
Altered mitochondrial function contributes greatly to pathogenesis and progression of colorectal cancer. In this study, we report a functional pool of Src homology 2 domain-containing F (SHF) in mitochondria controlling the response of colorectal can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cc025c75e1efe8f29675c101337fa1
https://pubmed.ncbi.nlm.nih.gov/36527512
https://pubmed.ncbi.nlm.nih.gov/36527512
Autor:
Stefan Günther, Thomas Braun, Yanhan Jia, Julio Cordero, Ludger Fink, Thomas Boettger, Rajkumar Savai, Boyan K. Garvalov, Werner Seeger, Anshu Singh, Alina Asafova, Luca Caputo, Gergana Dobreva, Till Acker, Guillermo Barreto, Joaquim S. L. Vong
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2019, 216 (6), pp.1377-1395. ⟨10.1084/jem.20181394⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2019, 216 (6), pp.1377-1395. ⟨10.1084/jem.20181394⟩
Jia et al. demonstrate that lamin B1 acts as a tumor suppressor in lung cancer. Lamin B1 loss promotes lung cancer development and metastasis by loss of PRC2 recruitment to chromatin and activation of the RET/p38 signaling axis.
Although abnorma
Although abnorma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fbb3deae67cdb59fea3b4810d4460b
http://europepmc.org/articles/PMC6547854
http://europepmc.org/articles/PMC6547854
Autor:
Zhenyu Zhu, Qingsheng Hou, Bishi Wang, Changhao Li, Luguang Liu, Weipeng Gong, Jie Chai, Hongliang Guo, Yanhan Jia
Publikováno v:
Life Science Alliance. 5:e202201413
Mitochondrial respiration and metabolism play a key role in the pathogenesis and progression of colon adenocarcinoma (COAD). Here, we report a functional pool of FKBP4, a co-chaperone protein, in the mitochondrial intermembrane space (IMS) of colon c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683e412ca10c0c289c5171bdc902dd1d
https://doi.org/10.26508/lsa.202201413
https://doi.org/10.26508/lsa.202201413
Autor:
Hui Peng, Chunxia Qiao, Yali Li, Tingting Zhou, Yan Li, Qing Zhao, Guijun Liu, Yanhan Jia, Yan Zhang, Jiannan Feng, Guojiang Chen, Qiuping Zhang
Publikováno v:
Biochemical and biophysical research communications. 436(4)
Trastuzumab (Herceptin®) has demonstrated clinical potential in several types of HER2-overexpressing human cancers. However, primary and acquired resistance occurs in many HER2-positive patients with regimens. To investigate the possible mechanism o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0148c17a6ef71b8e14a7adcb337c2a0
https://pubmed.ncbi.nlm.nih.gov/23792093
https://pubmed.ncbi.nlm.nih.gov/23792093
Autor:
Zhengming Jiang, Xiaochun Cao, Meng Hu, Chaohua Deng, Qiuping Zhang, Yanhan Jia, Yanping Liu, Shengwu Liu, Rongfei Han, Liang He
Publikováno v:
Leukemialymphoma. 52(7)
Multidrug resistance (MDR) and multi-organ infiltration are the major obstacles to the successful treatment of leukemia. It is known that the drug efflux protein, P-glycoprotein (P-gp), and inhibitors of apoptosis proteins (IAPs) are involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5473f134aa690aca6ea87f3dd8fe87
https://pubmed.ncbi.nlm.nih.gov/21599575
https://pubmed.ncbi.nlm.nih.gov/21599575
Autor:
Mengxin Cheng, Ranran Wu, Yi Hu, Xiang Tao, Qiuping Zhang, Yanhan Jia, Jing Gan, Rongfei Han, Zhengming Jiang, Li Zhang
Publikováno v:
Leukemia research. 35(9)
We have previously demonstrated that CCR9 plays a pivotal role in drug resistance and invasion in human acute T-lymphocytic leukemia (T-ALL). In this study, we investigated whether the MOLT4 cells, which naturally express CCR9 at high levels, can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eeedf8e03bd0704865f85f7305a26da
https://pubmed.ncbi.nlm.nih.gov/21295855
https://pubmed.ncbi.nlm.nih.gov/21295855