Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Yangzom D"'
Autor:
Tyler Sniegowski, Devaraja Rajasekaran, Souad R. Sennoune, Sukumaran Sunitha, Fang Chen, Mohamed Fokar, Sudhir Kshirsagar, P. Hemachandra Reddy, Ksenija Korac, Mosharaf Mahmud Syed, Tanima Sharker, Vadivel Ganapathy, Yangzom D. Bhutia
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer growth and, as intermediates, connect glucose, lipid and nucleo
Externí odkaz:
https://doaj.org/article/8da0a1c1200e43b09d36b442c5a114e9
Publikováno v:
International Journal of COPD, Vol Volume 18, Pp 849-858 (2023)
Zhihan Jiang,1,* Xiaosen Wang,1,* Lijiao Zhang,1,* Drolma Yangzom,2,* Yanping Ning,2 Baiyan Su,3,4 Meijiao Li,5 Meilang ChuTso,2 Yahong Chen,1,6 Ying Liang,1,2,6 Yongchang Sun1,6 1Department of Respiratory and Critical Care Medicine,
Externí odkaz:
https://doaj.org/article/4e82037ec4ee48ed80e86a2865fd6640
Autor:
Nhi T. Nguyen, Souad R. Sennoune, Gunadharini Dharmalingam-Nandagopal, Sathish Sivaprakasam, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v:
Cells, Vol 13, Iss 11, p 951 (2024)
Mutations in p53 and KRAS are seen in most cases of colon cancer. The impact of these mutations on signaling pathways related to cancer growth has been studied in depth, but relatively less is known on their effects on amino acid transporters in canc
Externí odkaz:
https://doaj.org/article/e78e0cc245e34a90a1bcb127b16674cb
Autor:
Marilyn Mathew, Sathish Sivaprakasam, Gunadharini Dharmalingam-Nandagopal, Souad R. Sennoune, Nhi T. Nguyen, Valeria Jaramillo-Martinez, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 291 (2024)
The amino acid transporters SLC38A5 and SLC7A11 are upregulated in triple-negative breast cancer (TNBC). SLC38A5 transports glutamine, methionine, glycine and serine, and therefore activates mTOR signaling and induces epigenetic modifications. SLC7A1
Externí odkaz:
https://doaj.org/article/3daedfbc71a246f0a273bad44bddad1d
Publikováno v:
International Journal of COPD, Vol Volume 16, Pp 2445-2454 (2021)
Ying Liang,1,2 Drolma Yangzom,2 Lhamo Tsokyi,2 Yanping Ning,2 Baiyan Su,3,4 Shuai Luo,4 Bian Ma Cuo,2 Meilang ChuTso,2 Yanling Ding,1 Yahong Chen,1 Yongchang Sun1 1Department of Respiratory and Critical Care Medicine, Peking University Third Hospital
Externí odkaz:
https://doaj.org/article/0dc75ded0c204bc8a0d6ee6623d64a5c
Autor:
Rachel L. Washburn, Dalia Martinez-Marin, Tyler Sniegowski, Ksenija Korać, Alexis R. Rodriguez, Jonathan M. Miranda, Beverly S. Chilton, Robert K. Bright, Kevin Pruitt, Yangzom D. Bhutia, Jannette M. Dufour
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1650 (2023)
Transplantation is a clinical procedure that treats a variety of diseases yet is unattainable for many patients due to a nationwide organ shortage and the harsh side effects of chronic immune suppression. Xenografted pig organs are an attractive alte
Externí odkaz:
https://doaj.org/article/b54c88465c0646c0ae6edfd99d7c02ae
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 173-180 (2020)
Uric acid is the end product of purine catabolism and its plasma levels are maintained below its maximum solubility in water (6–7 mg/dl). The plasma levels are tightly regulated as the balance between the rate of production and the rate of excretio
Externí odkaz:
https://doaj.org/article/ee6ce2c44c8f44f7b938ab7b18515f7d
Autor:
Yangzom D. Bhutia, Jiro Ogura, Paul J. Grippo, Carolina Torres, Toshihiro Sato, Mitchell Wachtel, Sabarish Ramachandran, Ellappan Babu, Sathish Sivaprakasam, Devaraja Rajasekaran, Bradley Schniers, Nhu On, Logan Smoot, Muthusamy Thangaraju, Jaya P. Gnana-Prakasam, Vadivel Ganapathy
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 237-251 (2020)
Based on the evidence that hemochromatosis, an iron-overload disease, drives hepatocellular carcinoma, we hypothesized that chronic exposure to excess iron, either due to genetic or environmental causes, predisposes an individual to cancer. Using pan
Externí odkaz:
https://doaj.org/article/fa207eb435da45528dce5dad9ee9ba3b
Autor:
Jiro Ogura, Ellappan Babu, Seiji Miyauchi, Sabarish Ramachandran, Elizebeta Nemeth, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract NaCT is a Na+-coupled transporter for citrate expressed in hepatocytes and neurons. It is the mammalian ortholog of INDY (I’m Not Dead Yet), a transporter which modifies lifespan in Drosophila. Here we describe a hitherto unknown transport
Externí odkaz:
https://doaj.org/article/ce0a9e30d5a64551b8dba0593afbfdc6
Autor:
Yangzom D. Bhutia, Marilyn Mathew, Sathish Sivaprakasam, Sabarish Ramachandran, Vadivel Ganapathy
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 235 (2022)
Amino acid transporters are expressed in mammalian cells not only in the plasma membrane but also in intracellular membranes. The conventional function of these transporters is to transfer their amino acid substrates across the lipid bilayer; the dir
Externí odkaz:
https://doaj.org/article/1fa84197984d4a1e9bd2729c89550a0f