Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yangxiao Hou"'
Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes
Autor:
Yangxiao Hou, Dong Wei, Zhaoqi Zhang, Tong Lei, Sihong Li, Jiaming Bao, Han Guo, Liang Tan, Xubiao Xie, Yuan Zhuang, Zhongbing Lu, Yong Zhao
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113658- (2024)
Summary: Poor skin wound healing, which is common in patients with diabetes, is related to imbalanced macrophage polarization. Here, we find that nutrition sensor GCN2 (general control nonderepressible 2) and its downstream are significantly upregula
Externí odkaz:
https://doaj.org/article/96a8e386ee1540f286a1a761be31fbbe
Publikováno v:
Engineering, Vol 10, Iss , Pp 21-29 (2022)
Innate immune cells are critical for transplant response. As an important cellular component of innate immune cells, macrophages are the predominate infiltrated cells in allografts, and macrophage accumulation in allografts is negatively associated w
Externí odkaz:
https://doaj.org/article/19a2eba021e34f899d19cee6d22a8577
Autor:
Yangxiao Hou, Dong Wei, Zhaoqi Zhang, Han Guo, Sihong Li, Jiayu Zhang, Peng Zhang, Lianfeng Zhang, Yong Zhao
Publikováno v:
Cell reports. 41(7)
Fatty acids (FAs) are widely involved in diverse biological functions. In mice with myeloid-specific deletion of fatty acid-binding protein 5 (FABP5), OVA-induced allergic airway inflammation (AAI) is significantly exacerbated by increasing alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2a4f307295a268f164150a459dbf11
https://pubmed.ncbi.nlm.nih.gov/36384126
https://pubmed.ncbi.nlm.nih.gov/36384126
Autor:
Yangxiao Hou, Dong Wei, Elhusseny A. Bossila, Zhaoqi Zhang, Sihong Li, Jiaming Bao, Huawen Xu, Lianfeng Zhang, Yong Zhao
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950).
Fatty acid binding protein 5 (FABP5) is mainly involved in the uptake, transport, and metabolism of fatty acid in the cytoplasm, and its role in immune cells has been recognized in recent years. However, the role of FABP5 in macrophage inflammation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72905ab4c353b08076856484ba9a67b
https://pubmed.ncbi.nlm.nih.gov/36280252
https://pubmed.ncbi.nlm.nih.gov/36280252
Publikováno v:
International Journal of Molecular Sciences. 24:4285
The serine/threonine-protein kinase general control nonderepressible 2 (GCN2) is a well-known stress sensor that responds to amino acid starvation and other stresses, making it critical to the maintenance of cellular and organismal homeostasis. More
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::199ced0a5d8f3a64392765652ecae560
https://doi.org/10.3390/ijms24054285
https://doi.org/10.3390/ijms24054285
Autor:
Liang, Tan, Yanan, Xu, Gongbin, Lan, Hongxia, Wang, Zhanfeng, Liang, Zhaoqi, Zhang, Qianchuan, Tian, Yangxiao, Hou, Yong, Zhao, Xubiao, Xie
Publikováno v:
Aging and disease. 13(5)
Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by inactivating mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::942cf6cec26b4b63aa8dcc01795c4294
https://pubmed.ncbi.nlm.nih.gov/36186130
https://pubmed.ncbi.nlm.nih.gov/36186130
Publikováno v:
Journal of Allergy and Clinical Immunology. 144:1091-1105
Background TH9 cells have emerged as important mediators of allergic airway inflammation. There is evidence that general control nonderepressible 2 (GCN2) affects the immune response under some stress conditions. However, whether GCN2 regulates CD4+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8ca653b00eef80f838c23d20f7668a
https://doi.org/10.1016/j.jaci.2019.04.028
https://doi.org/10.1016/j.jaci.2019.04.028
Autor:
Liang Tan, Yanan Xu, Gongbin Lan, Hongxia Wang, Zhanfeng Liang, Zhaoqi Zhang, Qianchuan Tian, Yangxiao Hou, Yong Zhao, Xubiao Xie
Publikováno v:
Aging & Disease; Oct2022, Vol. 13 Issue 5, p1562-1575, 14p
Autor:
Xubiao Xie, Yong Zhao, Yangxiao Hou, Qianchuan Tian, Zhaoqi Zhang, Zhanfeng Liang, Hongxia Wang, Gongbin Lan, Yanan Xu, Liang Tan
Publikováno v:
Aging and disease. 13:1562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adfe1e603b35a17ceeee4e17e0f15818
https://doi.org/10.14336/ad.2022.0224
https://doi.org/10.14336/ad.2022.0224
Autor:
Peng, Wang, Yana, Xu, Jiayu, Zhang, Lu, Shi, Tong, Lei, Yangxiao, Hou, Zhongbing, Lu, Yong, Zhao
Publikováno v:
The Journal of allergy and clinical immunology. 144(4)
TWe sought to clarify the regulatory roles of GCN2 in CD4The effects of GCN2 in differentiation of TGCN2 deficiency significantly inhibited differentiation of TOur results reveal a novel role of GCN2 in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b43e887f420fa258d8b65712130cc5f5
https://pubmed.ncbi.nlm.nih.gov/33436164
https://pubmed.ncbi.nlm.nih.gov/33436164