Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yangpo, Cao"'
Autor:
Chaoshan Han, Junjie Yang, Tingting Yin, Junqing An, Aijun Qiao, Yangpo Cao, Yuliang Feng, Haocheng Lu, Ying Wang, Liang Yang, Gangjian Qin
Publikováno v:
Extracellular Vesicle, Vol 2, Iss , Pp 100031- (2023)
Exosomes (Exo) are important mediators of inter-cellular communications; however, no effective method is available for isolating, thus characterizing, cellular-specific exosomes in vivo. Since CD63 is a reliable marker for exosomes, we have developed
Externí odkaz:
https://doaj.org/article/a14d6b7751fe4a4ca2d113c42b81d36c
Autor:
Ruxia Liu, Chunling Xu, Weilin Zhang, Yangpo Cao, Jingjing Ye, Bo Li, Shi Jia, Lin Weng, Yingying Liu, Lei Liu, Ming Zheng
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-11 (2022)
Abstract Hypoxic pulmonary hypertension (PH) is a progressive disease characterized by hyper-proliferation of pulmonary vascular cells including pulmonary artery smooth muscle cells (PASMCs) and can lead to right heart failure and early death. Select
Externí odkaz:
https://doaj.org/article/e4f8282587a449919f411ed665d505d0
Autor:
Yi Wang, Mingming Zhang, Rong Wang, Jing Lin, Qing Ma, Haipeng Guo, Huihui Huang, Zhuomin Liang, Yangpo Cao, Xiaoran Zhang, Yao Wei Lu, Jianming Liu, Feng Xiao, Hualin Yan, Dimitrova, Nadya, Zhan-Peng Huang, Mably, John D., Pu, William T., Da-Zhi Wang
Publikováno v:
Circulation Research; 7/19/2024, Vol. 135 Issue 3, p434-449, 16p
Autor:
Pingzhu Zhou, Yan Zhang, Isha Sethi, Lincai Ye, Michael A. Trembley, Yangpo Cao, Brynn N. Akerberg, Feng Xiao, Xiaoran Zhang, Kai Li, Blake D. Jardin, Neil Mazumdar, Qing Ma, Aibin He, Bin Zhou, William T. Pu
Publikováno v:
Circulation research. 131(11)
Background: The pioneer transcription factor (TF) GATA4 (GATA Binding Protein 4) is expressed in multiple cardiovascular lineages and is essential for heart development. GATA4 lineage-specific occupancy in the developing heart underlies its lineage s
Autor:
Yangpo Cao, Xiaoran Zhang, Brynn N. Akerberg, Haiyun Yuan, Tomoya Sakamoto, Feng Xiao, Nathan J. VanDusen, Pingzhu Zhou, Mason E. Sweat, Yi Wang, Maksymilian Prondzynski, Jian Chen, Yan Zhang, Peizhe Wang, Daniel P. Kelly, William T. Pu
Publikováno v:
Circulation. 147:881-896
Background: Cardiac chamber-selective transcriptional programs underpin the structural and functional differences between atrial and ventricular cardiomyocytes (aCMs and vCMs). The mechanisms responsible for these chamber-selective transcriptional pr
Autor:
Mason E. Sweat, Yangpo Cao, Xiaoran Zhang, Ozanna Burnicka-Turek, Carlos Perez-Cervantes, Brynn N. Akerberg, Qing Ma, Hiroko Wakimoto, Joshua M. Gorham, Mi Kyoung Song, Michael A. Trembley, Peizhe Wang, Fujian Lu, Matteo Gianeselli, Maksymilian Prondzynski, Raul H. Bortolin, Jonathan G. Seidman, Christine E. Seidman, Ivan P. Moskowitz, William T. Pu
Publikováno v:
bioRxiv
Understanding how the atrial and ventricular chambers of the heart maintain their distinct identity is a prerequisite for treating chamber-specific diseases. Here, we selectively inactivated the transcription factorTbx5in the atrial working myocardiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e019c2713c76df1072f0d0d59e6070
https://europepmc.org/articles/PMC10153240/
https://europepmc.org/articles/PMC10153240/
Autor:
Yuxuan Guo, Yangpo Cao, Blake D Jardin, Xiaoran Zhang, Pingzhu Zhou, Silvia Guatimosim, Junsen Lin, Zhan Chen, Yueyang Zhang, Neil Mazumdar, Fujian Lu, Qing Ma, Yao-Wei Lu, Mingming Zhao, Da-Zhi Wang, Erdan Dong, William T Pu
Publikováno v:
Cardiovasc Res
Calcium handling capacity is a major gauge of cardiomyocyte maturity. Ryanodine receptor 2 (RYR2) is the predominant calcium channel that releases calcium from the sarcoplasmic reticulum/endoplasmic reticulum (SR/ER) to activate cardiomyocyte contrac
Autor:
Chunling Xu, Yangpo Cao, Ruxia Liu, Lei Liu, Weilin Zhang, Xuan Fang, Shi Jia, Jingjing Ye, Yingying Liu, Lin Weng, Xue Qiao, Bo Li, Ming Zheng
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:1315-1326
Autophagy including mitophagy serves as an important regulatory mechanism in the heart to maintain the cellular homeostasis and to protect against heart damages caused by myocardial infarction (MI). The current study aims to dissect roles of general
Autor:
Pingzhu Zhou, Nathan J. VanDusen, Yanchun Zhang, Yangpo Cao, Isha Sethi, Rong Hu, Shuo Zhang, Guangyu Wang, Lincai Ye, Neil Mazumdar, Jian Chen, Xiaoran Zhang, Yuxuan Guo, Bin Li, Qing Ma, Julianna Y. Lee, Weiliang Gu, Guo-Cheng Yuan, Bing Ren, Kaifu Chen, William T. Pu
Publikováno v:
Developmental Cell. 58:898-914.e7
Autor:
Limei Liu, Shi Jia, Chunling Xu, Ruxia Liu, Xingzhong Zhang, Yangpo Cao, Qihua He, Jingjing Ye, Xue Qiao, Yingying Liu, Lin Weng, Cheng-Lin Zhang, Ming Zheng
Publikováno v:
Circulation Research. 125:728-743
Rationale: The constrained mitochondria in cardiomyocytes communicate with each other, through mitochondrial kissing or nanotunneling, forming a dynamically continuous network to share content and transfer signals. However, the molecular mechanism of