Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yangmian Yuan"'
Autor:
Yangmian Yuan, Yu Fan, Yihao Zhou, Rong Qiu, Wei Kang, Yu Liu, Yuchen Chen, Chenyu Wang, Jiajian Shi, Chengyu Liu, Yangkai Li, Min Wu, Kun Huang, Yong Liu, Ling Zheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Adipose-tissue is a central metabolic organ for whole-body energy homeostasis. Here, we find that highly expressed H1.2, a linker histone variant, senses thermogenic stimuli in beige and brown adipocytes. Adipocyte H1.2 regulates thermogenic
Externí odkaz:
https://doaj.org/article/4a355bfbf141477ea8a1ccf11361a75b
Autor:
Qing Wang, Yuchen Chen, Yunhao Xie, Dong Yang, Yuyan Sun, Yangmian Yuan, Hong Chen, Yu Zhang, Kun Huang, Ling Zheng
Publikováno v:
Cancer Science. 113:1679-1692
Linker histone H1.2 (H1.2), encoded by HIST1H1C (H1C), is a major H1 variant in somatic cells. Among five histone H1 somatic variants, upregulated H1.2 was found in human hepatocellular carcinoma (HCC) samples and in a diethylnitrosamine (DEN)-induce
Autor:
Yu Fan, Yangmian Yuan, Mingrui Xiong, Muchuan Jin, Donge Zhang, Dong Yang, Chengyu Liu, Petersen, Robert B., Kun Huang, Anlin Peng, Ling Zheng
Publikováno v:
Theranostics; 2023, Vol. 13 Issue 15, p5348-5364, 17p
Autor:
Jiao Wang, Mingrui Xiong, Yu Fan, Chengyu Liu, Qing Wang, Dong Yang, Yangmian Yuan, Yixue Huang, Shun Wang, Yu Zhang, Shuxuan Niu, Junqiu Yue, Hua Su, Chun Zhang, Hong Chen, Ling Zheng, Kun Huang
Publikováno v:
Theranostics. 12(8)
Autor:
Peilian Guo, Yuchen Chen, Yu Sun, Yangmian Yuan, Dong Yang, Mengyuan Geng, Kun Huang, Robert B. Petersen, Ling Zheng
Publikováno v:
The FASEB Journal. 34:4732-4748
Repeated cycles of weight loss and regain, known as weight cycling, is often seen when people try to lose weight. The exact pathophysiological effects and the underlying mechanisms of weight cycling remain largely unclear. Here, we report that weight
Autor:
Yangmian Yuan, Mingrui Xiong, Ling Zheng, Robert B. Petersen, Chengyu Liu, Yu Fan, Kun Huang, Yuyan Sun, Xingrui Chen, Hong Chen
Publikováno v:
Molecular nutritionfood research. 65(16)
Scope DNA methylation contributes to obesity, but the role of the DNA demethylase ten-eleven translocation protein 1 (Tet1) in obesity remains unclear. Vitamin C is a cofactor for the Tet family of proteins, but whether vitamin C can be used to treat
Autor:
Yujuan Wei, Mengyuan Geng, Yu Sun, Jiao Wang, Hong Chen, Kun Huang, Yu Zhang, Mingrui Xiong, Ling Zheng, Chengyu Liu, Yangkai Li, Yangmian Yuan, Wenquan Zhang, Yuchen Chen
Publikováno v:
Diabetes. 69:35-47
Abnormalities of methyl-CpG binding protein 2 (Mecp2) cause neurological disorders with metabolic dysfunction; however, its role in adipose tissues remains unclear. Here, we report upregulated Mecp2 in white adipose tissues (WAT) of obese humans, as
Autor:
Ling Zheng, Kun Huang, Robert B. Petersen, Qing Wang, Yu Zhang, Hong Chen, Chong Liu, Yangmian Yuan, Dong Yang, Wenquan Zhang, Ada Admin
Crosstalk among different tissues and organs is a hotspot in metabolic research. Recent studies have revealed the regulatory roles of a number of myokines in metabolism. Here, we report that female mice muscle-specific lacking histone methylase G9a (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69391e16d4794a5ed3d9aaa20b0740df
https://doi.org/10.2337/figshare.12990842
https://doi.org/10.2337/figshare.12990842
Autor:
Qing Wang, Chong Liu, Yu Zhang, Wenquan Zhang, Dong Yang, Yangmian Yuan, Kun Huang, Robert B. Petersen, Ling Zheng, Hong Chen
Publikováno v:
Diabetes. 69(12)
Cross talk among different tissues and organs is a hotspot in metabolic research. Recent studies have revealed the regulatory roles of a number of myokines in metabolism. Here, we report that female mice lacking muscle-specific histone methylase G9a
Autor:
Chong Liu, Yangmian Yuan, Mingrui Xiong, Chun Zhang, Xiuqin Zhu, Yixue Huang, Yannan Qu, Chengyu Liu, Hua Su, Ling Zheng, Peng Yun, Kun Huang, Hong Chen
Publikováno v:
The Journal of physiology. 597(6)
Key points Diabetic kidney disease (DKD) is a major complication of diabetes. We found that UTX (ubiquitously transcribed tetratricopeptide repeat on chromosome X, also known as KDM6A), a histone demethylase, was upregulated in the renal mesangial an