Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Yangli Xie"'
Autor:
Mengtian Fan, Nana Geng, Xingyue Li, Danyang Yin, Yuyou Yang, Rong Jiang, Cheng Chen, Naibo Feng, Li Liang, Xiaoli Li, Fengtao Luo, Huabing Qi, Qiaoyan Tan, Yangli Xie, Fengjin Guo
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 464-478 (2024)
Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes, in which the Indian hedgehog (IHH) and parathyroid hormone-related protein-parathyroid hormone-1 receptor (PTHrP-PTH1R) feed
Externí odkaz:
https://doaj.org/article/0e9c70152c8f4b7cbfb4af286d8a2587
Autor:
Li Liang, Fengmei Zhang, Naibo Feng, Biao Kuang, Mengtian Fan, Cheng Chen, Yiming Pan, Pengfei Zhou, Nana Geng, Xingyue Li, Menglin Xian, Lin Deng, Xiaoli Li, Liang Kuang, Fengtao Luo, Qiaoyan Tan, Yangli Xie, Fengjin Guo
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 11, Pp 2376-2389 (2023)
Abstract Osteoarthritis (OA) is a full-joint, multifactorial, degenerative and inflammatory disease that seriously affects the quality of life of patients due to its disabling and pain-causing properties. ER stress has been reported to be closely rel
Externí odkaz:
https://doaj.org/article/eab01dc3044e46f092e390b771dbe2cc
Autor:
Ran Chen, Ya Tan, Yang Li, Junlan Huang, Liang Kuang, Zhenhong Ni, Haiyang Lan, Rui Long, Yangli Xie, Hangang Chen, Xiaoqing Luo, Lin Chen, Ying Tang, Siru Zhou
Publikováno v:
Journal of Orthopaedic Translation, Vol 36, Iss , Pp 164-176 (2022)
Background: Vismodegib, as an exogenous Indian hedgehog (Ihh) antagonist, has been approved by the Food and Drug Administration (FDA) for the clinical treatment of patients with basal cell carcinoma, and previous observations implicate the potential
Externí odkaz:
https://doaj.org/article/76d8e33049d84bf0bc6a8e83fd0770b5
Autor:
Meng Xu, Junlan Huang, Min Jin, Wanling Jiang, Fengtao Luo, Qiaoyan Tan, Ruobin Zhang, Xiaoqing Luo, Liang Kuang, Dali Zhang, Sen Liang, Huabing Qi, Hangang Chen, Zhenhong Ni, Nan Su, Jing Yang, Xiaolan Du, Bo Chen, Chuxia Deng, Yangli Xie, Lin Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Background Intervertebral disc degeneration (IVDD) can cause low back pain, a major public health concern. IVDD is characterized with loss of cells especially those in nucleus pulposus (NP), due to the limited proliferative potential and reg
Externí odkaz:
https://doaj.org/article/5af176bfbfd946d2b95711a95eef1201
Autor:
Zuqiang Wang, Hangang Chen, Qiaoyan Tan, Junlan Huang, Siru Zhou, Fengtao Luo, Dali Zhang, Jing Yang, Can Li, Bo Chen, Xianding Sun, Liang Kuang, Wanling Jiang, Zhenhong Ni, Quan Wang, Shuai Chen, Xiaolan Du, Di Chen, Chuxia Deng, Liangjun Yin, Lin Chen, Yangli Xie
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract The intervertebral disc (IVD) is the largest avascular tissue. Hypoxia-inducible factors (HIFs) play essential roles in regulating cellular adaptation in the IVD under physiological conditions. Disc degeneration disease (DDD) is one of the l
Externí odkaz:
https://doaj.org/article/52e2b7c0fd3b4e27a5856b515a2804d4
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Objective To explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.Design A cross-sectional study.Setting National Health and Nutrition Examination Surveys database.Participants 12 576 patients.Prim
Externí odkaz:
https://doaj.org/article/3d0620bc7642475bb34f588eed44317e
Autor:
Yibo Gan, Jian He, Jun Zhu, Zhengyang Xu, Zhong Wang, Jing Yan, Ou Hu, Zhijie Bai, Lin Chen, Yangli Xie, Min Jin, Shuo Huang, Bing Liu, Peng Liu
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract A comprehensive understanding of the cellular heterogeneity and molecular mechanisms underlying the development, homeostasis, and disease of human intervertebral disks (IVDs) remains challenging. Here, the transcriptomic landscape of 108 108
Externí odkaz:
https://doaj.org/article/39cebf5a460b4d77afebe833c2a9b910
Autor:
Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Different types of mesenchymal progenitors participate in ectopic bone formation. Here, the authors show Col2+ lineage cells adopt a lymphatic endothelium cell fate, which regulates local inflammatory microenvironment after trauma, thus influencing h
Externí odkaz:
https://doaj.org/article/98970981f1554eb68ed709ba30420a0f
Autor:
Xianding Sun, Yang Zhou, Ruobin Zhang, Zuqiang Wang, Meng Xu, Dali Zhang, Junlan Huang, Fengtao Luo, Fangfang Li, Zhenhong Ni, Siru Zhou, Hangang Chen, Shuai Chen, Liang Chen, Xiaolan Du, Bo Chen, Haiyang Huang, Peng Liu, Liangjun Yin, Juhui Qiu, Di Chen, Chuxia Deng, Yangli Xie, Lingfei Luo, Lin Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Congenital scoliosis is a complex genetic disorder characterized by vertebral malformation. Here, the authors demonstrate that loss of dstyk leads to scoliosis in zebrafish due to dysregulated biogenesis of notochord vacuoles and that DSTYK is requir
Externí odkaz:
https://doaj.org/article/ed0a4b1f8cee4de29d66e4c76ba8d534
Autor:
Bo Chen, Qiaoyan Tan, Hangang Chen, Fengtao Luo, Meng Xu, Jianhua Zhao, Peng Liu, Xianding Sun, Nan Su, Dali Zhang, Weili Fan, Mingyong Liu, Haiyang Huang, Zuqiang Wang, Junlan Huang, Ruobin Zhang, Can Li, Fangfang Li, Zhenhong Ni, Xiaolan Du, Min Jin, Jing Yang, Yangli Xie, Lin Chen
Publikováno v:
Journal of Orthopaedic Translation, Vol 17, Iss , Pp 103-111 (2019)
Objective: Scoliosis is a common disease characterized by spinal curvature with variable severities. There is no generally accepted theory about the physical origin of the spinal deformation of scoliosis. The aim of this study was to explore a new hy
Externí odkaz:
https://doaj.org/article/e754688612dd4390a3dc594727dbd0aa