Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Yangjin Bae"'
Autor:
Yangjin Bae, Huan‐Chang Zeng, Yi‐Ting Chen, Shamika Ketkar, Elda Munivez, Zhiyin Yu, Francis H. Gannon, Brendan H. Lee
Publikováno v:
JBMR Plus, Vol 6, Iss 5, Pp n/a-n/a (2022)
ABSTRACT The expression of microRNAs (miRNAs) is dysregulated in many types of cancers including osteosarcoma (OS) due to genetic and epigenetic alterations. Among these, miR‐34c, an effector of tumor suppressor P53 and an upstream negative regulat
Externí odkaz:
https://doaj.org/article/50f963bc89f94e309c57e014932ed12d
Autor:
Huan-Chang Zeng, Yangjin Bae, Brian C. Dawson, Yuqing Chen, Terry Bertin, Elda Munivez, Philippe M. Campeau, Jianning Tao, Rui Chen, Brendan H. Lee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Control of osteocyte differentiation is not well understood. Here the authors show that the miR-23 cluster represses the TGF-β signalling repressor Prdm16 in osteoblasts, thus enhancing osteocyte differentiation and a low bone mass phenotype.
Externí odkaz:
https://doaj.org/article/65e76af7312b408ab752cc27fdd3ab65
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 332 (2020)
Skeletal development is a complex process which requires the tight regulation of gene activation and suppression in response to local signaling pathways. Among these pathways, Notch signaling is implicated in governing cell fate determination, prolif
Externí odkaz:
https://doaj.org/article/9297c84904174d08a93e9f2b49040b71
Autor:
Yangjin Bae, Huan‐Chang Zeng, Yi‐Ting Chen, Shamika Ketkar, Elda Munivez, Zhiyin Yu, Francis H. Gannon, Brendan H. Lee
Publikováno v:
JBMR Plus. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce97803b0a8e4a4ba50ac46463c9940
https://doi.org/10.1002/jbm4.10623
https://doi.org/10.1002/jbm4.10623
Autor:
Monika Weisz-Hubshman, Adetutu T Egunsula, Brian Dawson, Alexis Castellon, Ming-Ming Jiang, Yuqing Chen-Evenson, Yu Zhiyin, Brendan Lee, Yangjin Bae
Publikováno v:
Hum Mol Genet
Loss-of-function mutations in DDRGK1 have been shown to cause Shohat type spondyloepimetaphyseal dysplasia (SEMD). In zebrafish, loss of function of ddrgk1 leads to defects in early cartilage development. Ddrgk1−/− mice show delayed mesenchymal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ed5aba78d411dc090faa4aa3f5f13f
https://europepmc.org/articles/PMC9402238/
https://europepmc.org/articles/PMC9402238/
Autor:
Shamika Ketkar, Yi-Ting Chen, Yangjin Bae, Zhiyin Yu, Elda Munivez, Huan-Chang Zeng, Francis H. Gannon, Brendan Lee
The expression of microRNAs (miRNAs) is dysregulated in many types of cancers including osteosarcoma (OS) due to genetic and epigenetic alterations. Among these, miR-34c, an effector of tumor suppressor P53 and an upstream negative regulator of Notch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b299341d8f4cfb12ad85e052bd6d45da
https://doi.org/10.1101/2021.05.24.445452
https://doi.org/10.1101/2021.05.24.445452
Autor:
Christopher M. McAndrew, Zhou Yu, Steven Mumm, Kathryn Diemer, Michael J. Gardner, Gabe Haller, Fei Wan, Melissa Sum, Yangjin Bae, Lauren E. Surface, Niki Song, Shenghui Duan, William M Ricci, Thijn R. Brummelkamp, Timothy R. Peterson, Noopur Raje, Margaret Huskey, Daniel A. Haber, Kristen M. Shannon, Sandeep Kumar, Christina L. Costantino, Jinmei Li, Jan E. Carette, Brendan Lee, Mahshid Mohseni, Jiwoong Park, Abbhirami Rajagopal, Damon T. Burrow, Malini Varadarajan, Kıvanç Birsoy, Jonathan C. Baker, Thomas B. Dodson, Charles Gu, Vinieth N. Bijanki, Cheng Lyu, Christina A. Gurnett, David M. Sabatini, Roberto Civitelli
Publikováno v:
PMC
Nitrogen-containing bisphosphonates (N-BPs), such as alendronate, are the most widely prescribed medications for diseases involving bone, with nearly 200 million prescriptions written annually. Recently, widespread use of N-BPs has been challenged du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2223613b886c4d52ad1ac9e7f0821f2
https://doi.org/10.1126/scitranslmed.aav9166
https://doi.org/10.1126/scitranslmed.aav9166
Publikováno v:
Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. :768-774
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726e5a58e3ae5fa7a27136efeaada1c3
https://doi.org/10.1002/9781119266594.ch99
https://doi.org/10.1002/9781119266594.ch99
Autor:
Alyssa A. Tran, Bert B.A. de Vries, Brendan Lee, Chester W. Brown, Philippe M. Campeau, Ronit Marom, Brett H. Graham, Ralitza H. Gavrilova, Mahim Jain, Marwan Shinawi, Justine Rousseau, Richard A. Gibbs, Andrew T. Gunter, I-Wen Song, Christine M. Eng, James T. Lu, Yangjin Bae, Jill A. Rosenfeld, Yuqing Chen, Yaping Yang, Servi J. C. Stevens, Julie D. Kaplan, Alexander P.A. Stegmann, Lindsay C. Burrage
Publikováno v:
Human Mutation. 38:1365-1371
Pathogenic variants in genes encoding components of the BRG1-associated factor (BAF) chromatin remodeling complex have been associated with intellectual disability syndromes. We identified heterozygous, novel variants in ACTL6A, a gene encoding a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fde797ac721a8aa7b576e648262ce44
https://doi.org/10.1002/humu.23282
https://doi.org/10.1002/humu.23282
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 2, p 332 (2020)
Biomolecules, Vol 10, Iss 2, p 332 (2020)
Skeletal development is a complex process which requires the tight regulation of gene activation and suppression in response to local signaling pathways. Among these pathways, Notch signaling is implicated in governing cell fate determination, prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dc053340572ff9011c13764d7fe4e3
https://doi.org/10.3390/biom10020332
https://doi.org/10.3390/biom10020332