Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yanghe Zhang"'
Autor:
Yunkuo Li, Yujie Pan, Xiangzhe Yang, Yuxiong Wang, Bin Liu, Yanghe Zhang, Xin Gao, Yishu Wang, Honglan Zhou, Faping Li
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Non-muscle myosin heavy chain IIA (MYH9), a member of the non-muscle myosin II (NM II) family, is widely expressed in cells. The interaction of MYH9 with actin in the cytoplasm can hydrolyze ATP, completing the conversion of chemical energy
Externí odkaz:
https://doaj.org/article/ae930ab11524406788385badbabc0255
Autor:
Guangtao Li, Hongxia Yang, Dan Zhang, Yanghe Zhang, Bin Liu, Yuxiong Wang, Honglan Zhou, Zhi-Xiang Xu, Yishu Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117079- (2024)
Macrophages are widely distributed throughout various tissues of the body, and mounting evidence suggests their involvement in regulating the tissue microenvironment, thereby influencing disease onset and progression through direct or indirect action
Externí odkaz:
https://doaj.org/article/87612f65e8bd44b383d99a4522600da1
Autor:
Qingfei Meng, Yanghe Zhang, Huihui Sun, Xiangzhe Yang, Shiming Hao, Bin Liu, Honglan Zhou, Yishu Wang, Zhi-Xiang Xu
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103108- (2024)
High-risk human papillomaviruses (HPVs) are the causative agents of cervical cancer. Here, we report that HPV16 E6E7 promotes cervical cancer cell proliferation by activating the pentose phosphate pathway (PPP). We found that HPV16 E6 activates the P
Externí odkaz:
https://doaj.org/article/ce699a359b1c4716aba411be9865233c
Autor:
Qingfei Meng, Huihui Sun, Yanghe Zhang, Xiangzhe Yang, Shiming Hao, Bin Liu, Honglan Zhou, Zhi-Xiang Xu, Yishu Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) is identified as an oncogene involved in multiple regulation of tumor progression, but specific mechanisms remain unclear in cervical cancer. Lactate-mediated lactylation
Externí odkaz:
https://doaj.org/article/154fd26c36004ebcb570c8d37b24fdbe
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from chromaffin cells, holding significant clinical importance due to their capacity for excessive catecholamine secretion and associated cardiovascular complicat
Externí odkaz:
https://doaj.org/article/3610e2be4d06404abdc4ae317f0d1b83
Autor:
Shiming Hao, Qingfei Meng, Huihui Sun, Yunkuo Li, Yao Li, Liting Gu, Bin Liu, Yanghe Zhang, Honglan Zhou, Zhixiang Xu, Yishu Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113607- (2022)
Transketolase (TKT) is an enzyme that is ubiquitously expressed in all living organisms and has been identified as an important regulator of cancer. Recent studies have shown that the TKT family includes the TKT gene and two TKT-like (TKTL) genes; TK
Externí odkaz:
https://doaj.org/article/390271cc2f5044e3b12ba50a1fa9f7e1
Autor:
Qingfei Meng, Yanghe Zhang, Shiming Hao, Huihui Sun, Bin Liu, Honglan Zhou, Yishu Wang, Zhi-Xiang Xu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP to synthesize ribonucleotides and maintain intracellular redox homeostasis. G6P
Externí odkaz:
https://doaj.org/article/a54f0251982943e2b9f8ec9a347c05d4
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101131- (2021)
Background: Live kinase B1 (LKB1) is a tumor suppressor that is mutated in Peutz-Jeghers syndrome (PJS) and a variety of cancers. Lkb1 encodes serine-threonine kinase (STK) 11 that activates AMP-activated protein kinase (AMPK) and its 13 superfamily
Externí odkaz:
https://doaj.org/article/d0cedc2cb2e44d65963737be041c0f28
Autor:
Yuxiong, Wang, Faping, Li, Bin, Liu, Yanghe, Zhang, Yao, Li, Yunkuo, Li, Yishu, Wang, Honglan, Zhou
Publikováno v:
In Biomedicine & Pharmacotherapy October 2023 166
Publikováno v:
Clinical and Translational Oncology. 24:2045-2054
The somatic mutation of liver kinase B1 (LKB1) has been implicated in various tumors, which is reflected in the survival, proliferation, and metastasis of tumor cells. However, the regulation of LKB1 in lipid metabolism, a process that is involved in