Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yangfei Xian"'
Autor:
Rao Fu, Kang Ciming, Hai Yu, Min You, Ruoyao Qi, Jixian Tang, Yangfei Xian, Yang Huang, Ningshao Xia, Xinchu Xiang, Yuanzhi Chen, Yangtao Wu, Tianying Zhang, Wang Yiwen, Quan Yuan, Wenxin Luo
Publikováno v:
Antibody Therapeutics
Background We have previously obtained a mouse anti-hepatitis B surface antigen (HBsAg) antibody E6F6 with long-lasting serum HBsAg clearance effects. The E6F6 epitope-based protein CR-T3-SEQ13 (HBsAg aa 113-135) vaccination therapy in cynomolgus mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12b70731e14a260b2cb32675cbc1d89
https://doi.org/10.1093/abt/tbab020
https://doi.org/10.1093/abt/tbab020
Autor:
Sean P. Harrison, Richard Siller, Yoshiaki Tanaka, Maria Eugenia Chollet, María Eugenia de la Morena-Barrio, Yangfei Xiang, Benjamin Patterson, Elisabeth Andersen, Carlos Bravo-Pérez, Henning Kempf, Kathrine S. Åsrud, Oleg Lunov, Alexandr Dejneka, Marie-Christine Mowinckel, Benedicte Stavik, Per Morten Sandset, Espen Melum, Saphira Baumgarten, Flavio Bonanini, Dorota Kurek, Santosh Mathapati, Runar Almaas, Kulbhushan Sharma, Steven R. Wilson, Frøydis S. Skottvoll, Ida C. Boger, Inger Lise Bogen, Tuula A. Nyman, Jun Jie Wu, Ales Bezrouk, Dana Cizkova, Javier Corral, Jaroslav Mokry, Robert Zweigerdt, In-Hyun Park, Gareth J. Sullivan
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 9, Pp 2005-2024 (2023)
Abstract The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, including the liver. Current
Externí odkaz:
https://doaj.org/article/807e8461f64a4203a1ae380b8b984277
Autor:
Yuanzhi Chen, Xinchu Xiang, Ruoyao Qi, Yiwen Wang, Yang Huang, Min You, Yangfei Xian, Yangtao Wu, Rao Fu, Ciming Kang, Jixian Tang, Hai Yu, Tianying Zhang, Quan Yuan, Wenxin Luo, Ningshao Xia
Publikováno v:
Antibody Therapeutics; Oct2021, Vol. 4 Issue 4, p197-207, 11p, 1 Chart, 5 Graphs
Autor:
Leon Tejwani, Youngseob Jung, Hiroshi Kokubu, Sowmithra Sowmithra, Luhan Ni, Changwoo Lee, Benjamin Sanders, Paul J. Lee, Yangfei Xiang, Kimberly Luttik, Armand Soriano, Jennifer Yoon, Junhyun Park, Hannah H. Ro, Hyoungseok Ju, Clara Liao, Sofia Massaro Tieze, Frank Rigo, Paymaan Jafar-Nejad, Janghoo Lim
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
Protein aggregation is a hallmark of many neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). Although mutations in TARDBP, encoding transactive response DNA-binding protein 43 kDa (TDP-43), account for less than 1% of all ALS
Externí odkaz:
https://doaj.org/article/3422673f0c504358a6b5a37951131574
Autor:
Xiaoya Zhao, Zhenwu Zhang, Qian Zhu, Yurui Luo, Qinying Ye, Shuxiang Shi, Xueyang He, Jing Zhu, Duo Zhang, Wei Xia, Yiqin Zhang, Linlin Jiang, Long Cui, Yinghui Ye, Yangfei Xiang, Junhao Hu, Jian Zhang, Chao-Po Lin
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112546- (2023)
Summary: Ruptured ectopic pregnancy (REP), a pregnancy complication caused by aberrant implantation, deep invasion, and overgrowth of embryos in fallopian tubes, could lead to rupture of fallopian tubes and accounts for 4%–10% of pregnancy-related
Externí odkaz:
https://doaj.org/article/76e4026f5efe439a9351fdcf00917968
Autor:
Xingjian Bi, Lin Xia, Yuanzhi Chen, Daning Wang, Wenxin Luo, Zheng Fu, Hai Yu, Shaowei Li, Zhiqiang An, Yangfei Xian, Ningshao Xia, Xiaofen Huang, Xinlin Liu, Qinjian Zhao
Publikováno v:
Scientific Reports
The presence of neutralizing epitopes in human papillomavirus (HPV) L1 virus-like particles (VLPs) is the structural basis of prophylactic vaccines. An anti-HPV16 neutralizing monoclonal antibody (N-mAb) 26D1 was isolated from a memory B cell of a hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863998bca1dff7bbde8d35539b78112f
Publikováno v:
Cell Regeneration, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Studying the etiology of human neurodevelopmental diseases has long been a challenging task due to the brain’s complexity and its limited accessibility. Human pluripotent stem cells (hPSCs)-derived brain organoids are capable of recapitula
Externí odkaz:
https://doaj.org/article/e9e12c7c1cef42d183a482130f39fb71
Autor:
Bilal Cakir, Yoshiaki Tanaka, Ferdi Ridvan Kiral, Yangfei Xiang, Onur Dagliyan, Juan Wang, Maria Lee, Allison M. Greaney, Woo Sub Yang, Catherine duBoulay, Mehmet Hamdi Kural, Benjamin Patterson, Mei Zhong, Jonghun Kim, Yalai Bai, Wang Min, Laura E. Niklason, Prabir Patra, In-Hyun Park
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The study of human microglia function in health and disease is limited by the availability of sound models. Here, the authors develop a method to generate functional microglia in human cortical organoids and investigate the role of human microglia du
Externí odkaz:
https://doaj.org/article/f7e442e71a714aed94079c5c43728648
Autor:
Jialin Sun, Sivan Osenberg, Austin Irwin, Li-Hua Ma, Nigel Lee, Yangfei Xiang, Feng Li, Ying-Wooi Wan, In-Hyun Park, Mirjana Maletic-Savatic, Nurit Ballas
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111942- (2023)
Summary: Mutations in the MECP2 gene underlie a spectrum of neurodevelopmental disorders, most commonly Rett syndrome (RTT). We ask whether MECP2 mutations interfere with human astrocyte developmental maturation, thereby affecting their ability to su
Externí odkaz:
https://doaj.org/article/1fbbe2c170cb467c877ec479802254ec
Autor:
Yolpanhchana Lim, Jennifer E. Beane-Ebel, Yoshiaki Tanaka, Boting Ning, Christopher R. Husted, David C. Henderson, Yangfei Xiang, In-Hyun Park, Lindsay A. Farrer, Huiping Zhang
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Transcriptomic changes in specific brain regions can influence the risk of alcohol use disorder (AUD), but the underlying mechanism is not fully understood. We investigated AUD-associated miRNA–mRNA regulatory networks in multiple brain re
Externí odkaz:
https://doaj.org/article/e74b2297dd6e42a391971ab49712c1fb