Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Yangfan Zhou"'
Autor:
Liang Zhao, Yizhen Pang, Yangfan Zhou, Jianhao Chen, Hao Fu, Wei Guo, Weizhi Xu, Xin Xue, Guoqiang Su, Long Sun, Hua Wu, Jingjing Zhang, Zhanxiang Wang, Qin Lin, Xiaoyuan Chen, Haojun Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Radiotherapy combined with immune checkpoint blockade holds great promise for synergistic antitumor efficacy. Targeted radionuclide therapy delivers radiation directly to tumor sites. LNC1004 is a fibroblast activation protein (FAP)-targetin
Externí odkaz:
https://doaj.org/article/049546472d584436bd411dda0713b427
A Markov random field based method for removing invalid unwrapping phase points in 3D reconstruction
Publikováno v:
IET Image Processing, Vol 17, Iss 12, Pp 3477-3487 (2023)
Abstract Fringe projection profilometry is widely used in 3D structured light due to its fast speed and accuracy. However, in the process of phase unwrapping, it is easy to cause invalid points in the edges and shadows of objects, which leads to erro
Externí odkaz:
https://doaj.org/article/1d22af33a5214b5583f0b241d074325d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Genome-wide clustered regularly interspaced short palindromic repeats (CRISPR)-based knockout screening is revolting the genetic analysis of a cellular or molecular phenotype in question but is challenged by the large size of single-guide RN
Externí odkaz:
https://doaj.org/article/5077d345502647e88b094a61c32c87fc
Autor:
Jianbo Li, Panfeng Wu, Zhoutao Cao, Guanlan Huang, Zhike Lu, Jianfeng Yan, Heng Zhang, Yangfan Zhou, Rong Liu, Hui Chen, Lijia Ma, Mengcheng Luo
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113765- (2024)
Summary: The increasing emergence of Cas9 variants has attracted broad interest, as these variants were designed to expand CRISPR applications. New Cas9 variants typically feature higher editing efficiency, improved editing specificity, or alternativ
Externí odkaz:
https://doaj.org/article/c2ab74585f1c42a3b0819013104c6643
Publikováno v:
Stem Cell Research, Vol 74, Iss , Pp 103284- (2024)
TGF-β-activated kinase 1 binding protein 2 (TAB2) is an intermediate protein that connects TNFR1 and other receptor signals to the TGF-β-activated kinase 1 (TAK1) signaling complex. TAB2 has been proved clinically relevant to congenital heart defec
Externí odkaz:
https://doaj.org/article/6cb3fdac73cc4712bd010f7a65f2f6c7
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2024)
Endocytosis constitutes a cellular process in which cells selectively encapsulate surface substances into endocytic vesicles, also known as endosomes, thereby modulating their interaction with the environment. Platelets, as pivotal hematologic elemen
Externí odkaz:
https://doaj.org/article/dac0430608dd4f19a504a1618fd4b956
Autor:
Heng Zhang, Jianfeng Yan, Zhike Lu, Yangfan Zhou, Qingfeng Zhang, Tingting Cui, Yini Li, Hui Chen, Lijia Ma
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-20 (2023)
Abstract Life science studies involving clustered regularly interspaced short palindromic repeat (CRISPR) editing generally apply the best-performing guide RNA (gRNA) for a gene of interest. Computational models are combined with massive experimental
Externí odkaz:
https://doaj.org/article/d881e6e86c01463aa5b6f0f3696e4ad5
Autor:
Guixiang Xu, Xin Zhang, Shuyang Sun, Yangfan Zhou, Yongfeng Liu, Hangwang Yang, Zhenguo Huang, Fang Fang, Wenping Sun, Zijiang Hong, Mingxia Gao, Hongge Pan
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Garnet‐type oxide Li6.4La3Zr1.4Ta0.6O12 (LLZTO) features superior ionic conductivity and good stability toward lithium (Li) metal, but requires high‐temperature sintering (≈1200 °C) that induces high fabrication cost, poor mechanical
Externí odkaz:
https://doaj.org/article/1b4e6c6ff0f942a38990386692a5d075
Autor:
Zhenxing Yu, Zhike Lu, Jingjing Li, Yingying Wang, Panfeng Wu, Yini Li, Yangfan Zhou, Bailun Li, Heng Zhang, Yingzheng Liu, Lijia Ma
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
It is still a challenge to accurately identify off-target endonuclease edits. Here the authors report PEAC-seq using a Prime Editor to insert a tag to the editing sites and enrich the tagged regions with site-specific primers for sequencing: they sho
Externí odkaz:
https://doaj.org/article/906145db752d453cb2223b7e2782e62c
Publikováno v:
Frontiers in Surgery, Vol 9 (2023)
BackgroundRecent studies have found that 5-methylcytosine (m5C) modulators are associated with the prognosis and treatment of cancer. However, the relevance of m5C modulators in sarcoma prognosis and the tumour microenvironment is unclear.MethodsWe s
Externí odkaz:
https://doaj.org/article/85d0d4fb32d549b2a884a0a35dde2f1d